Various biological pathways affected in response to exposure to serotonin reuptake inhibitors. After exposure the genes lace, cDASE, GlcT-1, ldh, Acon, Ddc, Fbp, and thiolase are upregulated, while Pfk, UGP, and ATPC are downregulated.
f52
serotonin metabolic pathway
PW:0000410
Pathway Ontology
23855649
PubMed
Identification of metabolic pathways in Daphnia magna explaining hormetic effects of selective serotonin reuptake inhibitors and 4-nonylphenol using transcriptomic and phenotypic responses.
Environ Sci Technol
2013
Campos B
Garcia-Reyero N
Rivetti C
Escalon L
Habib T
Tauler R
Tsakovski S
PiƱa B
Barata C