ArcPathVisio
Brace
Octagon
Ellipse
EndoplasmicReticulum
HexagonPathVisio
GolgiApparatus
MimDegradation
Mitochondria
Octagon
PentagonPathVisio
Rectangle
RoundedRectangle
SarcoplasmicReticulum
TrianglePathVisio
none
Examples of RB-E2F Complexes
inhibiting E2F-driven gene expression
Rb-E2F complex
RB1
ABL1
CDKN1B
MYC
JNK cascade
TP53
G1/S transition of mitotic cell cycle
DNA damage response, signal transduction
resulting in induction of apoptosis
histone H3-K9 methylation
MAPK13
CDKN1A
G1/S transition of mitotic cell cycle
DNA replication
CDT1
regulation of cyclin-dependent protein kinase activity
DNA repair
cell cycle checkpoint
M/G1 transition of mitotic cell cycle
mitotic cell cycle
DNA replication checkpoint
G2/M transition of mitotic cell cycle
MAP kinase activity
growth factor activity
bta-mir-21
RRM2
DHFR
TYMS
E2F3
TFDP1
CCNA2
CCNB2
TOP2A
RRM1
TTK
STMN1
MCM6
MCM7
CDC45L
MCM3
MCM4
POLE
ORC1
RPA1
CDK1
CDC7L1
WEE1
POLA1
PRIM1
POLE2
PLK4
CDC25B
NPAT
PCNA
E2F1
MSH6
PRKDC
BARD1
SMC2
SMC3
RFC4
RFC5
RFC3
CHEK1
SMC1A
MGC159566
SMARCA2
KIF4A
DCK
HMGB2
RABIF
HLTF
ANLN
HMGB1
FAF1
POLD3
H2AFZ
MDM2
RB1
E2F1
TFDP1
RB1
SKP2
RB1
CDKN1B
SKP2
ABL1
RB1
RAF1
RB1
MCM7
RB1
CDK2
CCNE1
RBP1
HDAC1
TFDP1
E2F1
RB1
RPA1
RPA2
RPA3
SAP30
SIN3A
RBBP7
RBBP4
RBP1
HDAC1
TFDP2
E2F1
RB1
CCNE2
CDC25A
CCNE1
CCND3
CDK1
CCDC6
CCNB1
DNMT1
RBP1
HDAC1
TFDP1
E2F1
RB1
HRMT1L1
RB1
SUV39H1
TFDP1
E2F1
RB1
CDK4
CCND1
MIR29B1
MIR29B2
TFDP1
E2F2
ZNF655
RB1
MDM2
TFDP1
E2F1
MDM2
TP53
G1/S transition of mitotic cell cycle
TFDP1
E2F1
TFDP1
E2F2
TFDP1
E2F1
regulation of cyclin-dependent protein kinase activity
mitotic spindle organization
TFDP2
E2F1
TFDP2
E2F2
TFDP2
E2F1
RBP1
HDAC1
TFDP1
E2F2
RB1
RBP1
HDAC1
TFDP1
E2F3
RB1
RBP1
HDAC1
TFDP2
E2F1
RB1
RBP1
HDAC1
TFDP2
E2F2
RB1
RBP1
HDAC1
TFDP2
E2F3
RB1
E2F2
TFDP1
RB1
E2F3
TFDP1
RB1
CDK6
CCND1
Examples of RB-E2F Complexes
promoting E2F-driven gene expression
Rb-E2F complex
Name: Retinoblastoma gene in cancer
Last Modified: 20220203104644
Organism: Bos taurus