This pathway describes the Fas induced apoptosis and interplay with Hsp27 in response to stress.
More info: [http://www.biocarta.com/pathfiles/h_hsp27Pathway.asp BioCarta].
Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP314 CPTAC Assay Portal]ed8Interim Symbol: Spna1 predicted and Name: spectrin alpha 1 (predicted)receptor (TNFRSF)-interacting serine-threonine kinase 2Interim Symbol: Arhgdib predicted and Name: Rho, GDP dissociation inhibitor (GDI) beta (predicted)e5bstress response pathwayPW:0000237Pathway Ontology10914538PubMedHeat shock proteins--modulators of apoptosis in tumour cells.Leukemia2000Creagh EMSheehan DCotter TG18803879PubMedRestoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres.BMC Cancer2008Ji QHao XMeng YZhang MDesano JFan DXu LFasL mediated signaling pathwayPW:0000681Pathway Ontology