Acetylcholine is an important neurotransmitter. It can be rapidly released in the synaptic cleft upon activation of the neuron. In the synaptic cleft the compound is degraded rapidly into choline and acetate, this is essential for proper neuronal functioning. Choline and Acetate are taken up into the cytosol and recycled for the next activation.This pathway was inferred from Homo sapiens pathway [http://wikipathways.org/instance/WP528_r79855 WP528(79855)] with a 100.0% conversion rate.dbcea7d01HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5130HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5161HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:43HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5160HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10400HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1119HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1103acetylcholine metabolic pathwayPW:0000408Pathway Ontology6867732PubMedCholine and cholinergic neurons.Science1983Blusztajn JKWurtman RJ23677775PubMedAcetyl-CoA the key factor for survival or death of cholinergic neurons in course of neurodegenerative diseases.Neurochem Res2013Szutowicz ABielarczyk HJankowska-Kulawy APawełczyk TRonowska A15590413PubMedAcetylcholine synthesis and possible functions during sea urchin development.Eur J Histochem2004Angelini CBaccetti BPiomboni PTrombino SAluigi MGStringara SGallus LFalugi C