Immune infiltration in pancreatic cancer (WP5285)
Homo sapiens
Immune cell infiltration in pancreatic cancer. Various factors are secreted in the tumor microenvironment (TME) of pancreatic ductal adenocarcinoma (PDAC) that can either stimulate or inhibit PDAC development. Alteration of PDAC development by immune cells can be direct and/or indirect. Used cell name abbreviations: MDSC = myeloid-derived suppressor cell, Treg = regulatory T cell, CAF = cancer associated fibroblast, PSC = pancreatic stellate cell, Th = CD4+ T helper cell.
Authors
Isabel Wassink , Martina Summer-Kutmon , Daniela Digles , and Eric WeitzActivity
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Organisms
Homo sapiensCommunities
CPTAC Diseases PancCanNetAnnotations
Cell Type Ontology
regulatory T cell neutrophil T-helper 1 cell fibroblast macrophage pancreatic stellate cell T-helper 17 cell T-helper 2 cell myeloid suppressor cellPathway Ontology
pancreatic cancer pathway immune response pathway disease pathwayDisease Ontology
pancreatic cancerReferences
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