Mitochondrial beta-oxidation (WP5241)

Homo sapiens

Authors

Conroy lipids , Egon Willighagen , Denise Slenter , and Eric Weitz

Activity

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Cited In

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

lipid metabolic pathway classic metabolic pathway fatty acid beta degradation pathway

References

1. Isolation and expression of a cDNA encoding the precursor for a novel member (ACADSB) of the acyl-CoA dehydrogenase gene family. Rozen R, Vockley J, Zhou L, Milos R, Willard J, Fu K, et al. Genomics. 1994 Nov 15;24(2):280–7. PubMed Europe PMC Scholia
2. Delta 3, delta 2-enoyl-CoA isomerase is the protein that copurifies with human glutathione S-transferases from S-hexylglutathione affinity matrices. Takahashi Y, Hirata Y, Burstein Y, Listowsky I. Biochem J. 1994 Dec 15;304 ( Pt 3)(Pt 3):849–52. PubMed Europe PMC Scholia
3. Human short-chain L-3-hydroxyacyl-CoA dehydrogenase: cloning and characterization of the coding sequence. Vredendaal PJ, van den Berg IE, Malingré HE, Stroobants AK, Olde Weghuis DE, Berger R. Biochem Biophys Res Commun. 1996 Jun 25;223(3):718–23. PubMed Europe PMC Scholia
4. A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer’s disease. He XY, Schulz H, Yang SY. J Biol Chem. 1998 Apr 24;273(17):10741–6. PubMed Europe PMC Scholia
5. Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site. Alphey MS, Yu W, Byres E, Li D, Hunter WN. J Biol Chem. 2005 Jan 28;280(4):3068–77. PubMed Europe PMC Scholia
6. The crystal structure of human mitochondrial 3-ketoacyl-CoA thiolase (T1): insight into the reaction mechanism of its thiolase and thioesterase activities. Kiema TR, Harijan RK, Strozyk M, Fukao T, Alexson SEH, Wierenga RK. Acta Crystallogr D Biol Crystallogr. 2014 Dec 1;70(Pt 12):3212–25. PubMed Europe PMC Scholia
7. Clinical, biochemical and metabolic characterisation of a mild form of human short-chain enoyl-CoA hydratase deficiency: significance of increased N-acetyl-S-(2-carboxypropyl)cysteine excretion. Yamada K, Aiba K, Kitaura Y, Kondo Y, Nomura N, Nakamura Y, et al. J Med Genet. 2015 Oct;52(10):691–8. PubMed Europe PMC Scholia