Phospholipid biosynthesis (WP5201)
Saccharomyces cerevisiae
This phospholipid biosynthesis shows a schematic overview of the major pathways for phospholipid biosynthesis in yeast. The mainphospholipid biosynthesis pathway included in this figure is; phosphatidylcholine/phosphatidyl- ethanolamine (PC/PE) reacylation pathway. This figure shows the conversions and enzymatic reactions recquired for the PC/PE pathway.
Authors
Linda Kollenburg and Denise SlenterActivity
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Organisms
Saccharomyces cerevisiaeCommunities
Annotations
Pathway Ontology
glycerophospholipid metabolic pathway classic metabolic pathway lipid metabolic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| CDP-choline | Metabolite | chebi:58779 | |
| G3P | Metabolite | wikidata:Q794810 | |
| LPA | Metabolite | chebi:132742 | |
| CDP-ethanolamine(1−) | Metabolite | chebi:57876 | |
| LPE | Metabolite | chebi:131690 | |
| GPE | Metabolite | chebi:36314 | |
| PC | Metabolite | chebi:64423 | |
| CDP-DAG | Metabolite | chebi:17962 | |
| DAG | Metabolite | chebi:75475 | |
| LPC | Metabolite | chebi:132742 | |
| PE | Metabolite | chebi:16038 | |
| PG | Metabolite | chebi:73879 | |
| choline-P | Metabolite | chebi:34635 | |
| GPC | Metabolite | chebi:16870 | GPC is the abbreviation for glycerophosphocholine. This is an alternative name for choline alfoscerate |
| DHAP | Metabolite | chebi:16108 | |
| PA | Metabolite | chebi:132564 | |
| CL | Metabolite | chebi:28494 | |
| PS | Metabolite | chebi:72036 | |
| Choline | Metabolite | chebi:15354 | |
| PI | Metabolite | chebi:16749 | |
| LPC | Metabolite | chebi:132742 | |
| Choline | Metabolite | chebi:15354 | |
| LPE | Metabolite | chebi:131690 | |
| DAG | Metabolite | chebi:75475 | |
| GPC | Metabolite | chebi:16870 | GPC is the abbreviation for glycerophosphocholine. This is an alternative name for choline alfoscerate |
| GIT1 | GeneProduct | ensembl:YCR098C | |
| ALE1 | GeneProduct | ensembl:YOR175C | |
| SCT1 | GeneProduct | ensembl:YBL011W | |
| PSD2 | GeneProduct | ensembl:YGR170W | |
| GPCAT | GeneProduct | ensembl:YGR149W | |
| PAH1 | GeneProduct | ensembl:YMR165C | |
| DPP1 | GeneProduct | ensembl:YDR284C | |
| CDS1 | GeneProduct | ensembl:YBR029C | |
| GPT2 | GeneProduct | ensembl:YKR067W | |
| PSD1 | GeneProduct | ensembl:YNL169C | |
| HNM1 | GeneProduct | ensembl:YGL077C | |
| CPT1 | GeneProduct | ensembl:YNL130C | |
| CHO1 | GeneProduct | ensembl:YER026C | |
| LPP1 | GeneProduct | ensembl:YDR503C | |
| NTE1 | GeneProduct | ensembl:YML059C | |
| ALE1 | GeneProduct | ensembl:YOR175C |
References
- Identification of a novel GPCAT activity and a new pathway for phosphatidylcholine biosynthesis in S. cerevisiae. Stålberg K, Neal AC, Ronne H, Ståhl U. J Lipid Res. 2008 Aug;49(8):1794–806. PubMed Europe PMC Scholia