Lipid metabolism in senescent cells (WP5149)

Homo sapiens

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Description of the affected lipid metabolism in senecent cells.

Authors

Martina Summer-Kutmon and Eric Weitz

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

cellular senescence pathway lipid metabolic pathway

Participants
Query Drugst.One

Label Type Compact URI Comment
PUFA Metabolite chebi:26208
Oxylipin Metabolite chebi:61121
Free PUFA Metabolite chebi:26208
HRAS GeneProduct ensembl:ENSG00000174775
PLA2G3 GeneProduct ensembl:ENSG00000100078
PTGS2 GeneProduct ensembl:ENSG00000073756
CDKN1A GeneProduct ensembl:ENSG00000124762
SLCO2A1 GeneProduct ensembl:ENSG00000174640
ALOX5 GeneProduct ensembl:ENSG00000012779
TP53 GeneProduct ensembl:ENSG00000141510
PLA2G2D GeneProduct ensembl:ENSG00000117215
PLA2G4A GeneProduct ensembl:ENSG00000116711
PLA2G4C GeneProduct ensembl:ENSG00000105499
PLA2G4D GeneProduct ensembl:ENSG00000159337
PLA2G4E GeneProduct ensembl:ENSG00000188089
PLA2G4F GeneProduct ensembl:ENSG00000168907
PLA2G5 GeneProduct ensembl:ENSG00000127472
PLA2G6 GeneProduct ensembl:ENSG00000184381
PLA2G7 GeneProduct ensembl:ENSG00000146070
PLA2G10 GeneProduct ensembl:ENSG00000069764
PLA2G12A GeneProduct ensembl:ENSG00000123739
PLA2G12B GeneProduct ensembl:ENSG00000138308
PLA2G1B GeneProduct ensembl:ENSG00000170890

References

  1. The metabolic roots of senescence: mechanisms and opportunities for intervention. Wiley CD, Campisi J. Nat Metab. 2021 Oct;3(10):1290–301. PubMed Europe PMC Scholia