ID signaling pathway (WP512)

Mus musculus

Inhibitor of DNA binding (ID) proteins are members of the helix-loop-helix (HLH) family of proteins which lack a DNA binding domain themselves but bind to other family members inhibiting their DNA binding capacity. This family of proteins is comprised of IDs 1, 2, 3 and 4. They can be stimulated by ligands such as the Vascular Endothelial Growth Factor (VEGF), TGF beta and the T cell receptor. Source: NetPath


Akhilesh Pandey , Alex Pico , Christine Chichester , and Eric Weitz


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Mus musculus



Pathway Ontology

Inhibitor of DNA binding signaling pathway


Label Type Compact URI Comment
Id1 GeneProduct ncbigene:15901
Id2 GeneProduct ncbigene:15902
Id3 GeneProduct ncbigene:15903
Id4 GeneProduct ncbigene:15904
Id2 GeneProduct ncbigene:15902
Rb1 GeneProduct ncbigene:19645
Rbl2 GeneProduct ncbigene:19651
Rbl1 GeneProduct ncbigene:19650
Tcfe2a GeneProduct ncbigene:21423
Myod1 GeneProduct ncbigene:17927
Cdk2 GeneProduct ncbigene:12566
Ccna2 GeneProduct ncbigene:12428
Ccne1 GeneProduct ncbigene:12447
Elk1 GeneProduct ncbigene:13712
Elk4 GeneProduct ncbigene:13714
Elk3 GeneProduct ncbigene:13713
Psmd4 GeneProduct ncbigene:19185
Hes1 GeneProduct ncbigene:15205
Pax5 GeneProduct ncbigene:18507
Pax2 GeneProduct ncbigene:18504
Pax8 GeneProduct ncbigene:18510
Myf5 GeneProduct ncbigene:17877
Myf6 GeneProduct ncbigene:17878
Myog GeneProduct ncbigene:17928
Tcf12 GeneProduct ncbigene:21406
Srebf1 GeneProduct ncbigene:20787
Msc GeneProduct ncbigene:17681
Bmp2 GeneProduct ncbigene:12156
Bmpr2 GeneProduct ncbigene:12168
Vegfa GeneProduct ncbigene:22339
Flt1 GeneProduct ncbigene:14254
Kdr GeneProduct ncbigene:16542
Smad1 GeneProduct ncbigene:17125
Smad4 GeneProduct ncbigene:17128
Smad5 GeneProduct ncbigene:17129
Atf3 GeneProduct ncbigene:11910
Smad3 GeneProduct ncbigene:17127
Tgif1 GeneProduct ncbigene:21815
Acvrl1 GeneProduct ncbigene:11482
Smad4 GeneProduct ncbigene:17128
Smad5 GeneProduct ncbigene:17129
Smad1 GeneProduct ncbigene:17125
LCK GeneProduct ncbigene:16818
RAS GeneProduct ncbigene:19412
Igf1r GeneProduct ncbigene:16001
Igf1 GeneProduct ncbigene:16000
Irs1 GeneProduct ncbigene:16367
Ctnnb1 GeneProduct ncbigene:12387
Tert GeneProduct ncbigene:21752
Nfkb1 GeneProduct ncbigene:18033
Rela GeneProduct ncbigene:19697
Bmp6 GeneProduct ncbigene:12161
Cd40lg GeneProduct ncbigene:21947
Ngf GeneProduct ncbigene:18049
Atf3 GeneProduct ncbigene:11910
Smad3 GeneProduct ncbigene:17127
Egf GeneProduct ncbigene:13645
Tcf7l2 GeneProduct ncbigene:21416