Frustrated phagocytosis leading to malignant pleural mesothelioma (WP5091)
Adverse Outcome Pathway for malignant pleural mesothelioma, known to be initiated by asbestos and carbon nanotubes. This molecular AOP is based on https://aopwiki.org/aops/409
AuthorsMarvin Martens , Eric Weitz , and Alexandra Bosch
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CommunitiesAdverse Outcome Pathways
Cell Type Ontologymesothelial cell
Disease Ontologymalignant pleural mesothelioma
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- Do Carbon Nanotubes and Asbestos Fibers Exhibit Common Toxicity Mechanisms? Gupta SS, Singh KP, Gupta S, Dusinska M, Rahman Q. Nanomaterials (Basel). 2022 May 17;12(10):1708. PubMed Europe PMC Scholia