GPCRs, class A rhodopsin-like (WP473)

Rattus norvegicus

This pathway was created using the GPCRDB (Horn et al., 1998), (originally at The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.


Christine Chichester , Egon Willighagen , Denise Slenter , Eric Weitz , and Alex Pico


last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.


Rattus norvegicus



Pathway Ontology

G protein mediated signaling pathway


Label Type Compact URI Comment
Dopamine Metabolite chebi:18243
Bradykinin Metabolite chebi:3165
Prostaglandin Metabolite chebi:26333
Serotonin Metabolite chebi:28790
Angiotensin II Metabolite hmdb:HMDB0001035
Histamine Metabolite chebi:18295
Olr1467 GeneProduct ncbigene:287481
Rrh GeneProduct ncbigene:310869
Xcr1 GeneProduct ncbigene:301086
Ccr4 GeneProduct ncbigene:171054
Drd2 GeneProduct ncbigene:24318
Gpr52 GeneProduct ncbigene:680192
MC1R GeneProduct ncbigene:292083
P2ry10 GeneProduct ncbigene:317219
Oprm1 GeneProduct ncbigene:25601
F2rl1 GeneProduct ncbigene:116677
P2ry4 GeneProduct ncbigene:63843
Htr2b GeneProduct ncbigene:29581
Cysltr2 GeneProduct ncbigene:170926
Mtnr1b GeneProduct ncbigene:192646
Htr1f GeneProduct ncbigene:60448
Olr1730 GeneProduct ncbigene:294187
Cnr1 GeneProduct ncbigene:25248
Gpr85 GeneProduct ncbigene:64020
Cxcr5 GeneProduct ncbigene:29363
LOC685243 GeneProduct ncbigene:685243
GPR17 GeneProduct ncbigene:767613
P2ry6 GeneProduct ncbigene:117264
Galr2 GeneProduct ncbigene:29234
Sstr5 GeneProduct ncbigene:25354
Olr1086 GeneProduct ncbigene:299588
NTSR2 GeneProduct ncbigene:64636
Cx3cr1 GeneProduct ncbigene:171056
Gpr15 GeneProduct ncbigene:288181
Gpr37l1 GeneProduct ncbigene:252939
Sstr4 GeneProduct ncbigene:25555
GPR6 GeneProduct ncbigene:83683
Olr1201 GeneProduct ncbigene:405106
P2ry2 GeneProduct ncbigene:29597
Lpar5 GeneProduct ncbigene:500317
GPR39 GeneProduct ncbigene:288995
Sstr2 GeneProduct ncbigene:54305
Drd4 GeneProduct ncbigene:25432
Olr1075 GeneProduct ncbigene:299596
Ccr8 GeneProduct ncbigene:301066
Chrm2 GeneProduct ncbigene:81645
Hcrtr1 GeneProduct ncbigene:25593
Oprl1 GeneProduct ncbigene:29256
Cxcr3 GeneProduct ncbigene:84475
Mtnr1a GeneProduct ncbigene:114211
OPN1MW GeneProduct ncbigene:89810
Fpr1 GeneProduct ncbigene:292409
Oprk1 GeneProduct ncbigene:29335
F2RL3 GeneProduct ncbigene:116498
Ptger1 GeneProduct ncbigene:25637
Ptger4 GeneProduct ncbigene:84023
Rgr GeneProduct ncbigene:306307
Ptgfr GeneProduct ncbigene:25652
Olr836 GeneProduct ncbigene:298394
Cnr2 GeneProduct ncbigene:57302
ADRA2A GeneProduct ncbigene:25083
Htr4 GeneProduct ncbigene:25324
Olr231 GeneProduct ncbigene:293375
Adora1 GeneProduct ncbigene:29290
Nmbr GeneProduct ncbigene:25264
Nmur2 GeneProduct ncbigene:64042
Trhr GeneProduct ncbigene:25570
Opn4 GeneProduct ncbigene:192223
Htr1b GeneProduct ncbigene:25075
Gpr19 GeneProduct ncbigene:312787
Gpr22 GeneProduct ncbigene:298944
Rho GeneProduct ncbigene:24717
F2r GeneProduct ncbigene:25439
Adora2a GeneProduct ncbigene:25369
Fpr2 GeneProduct ncbigene:690158
Olr1073 GeneProduct ncbigene:405362
Sstr1 GeneProduct ncbigene:25033
Cmklr1 GeneProduct ncbigene:60669
Nmur1 GeneProduct ncbigene:65276
Adra2c GeneProduct ncbigene:24175
Adora3 GeneProduct ncbigene:25370
Gpr31 GeneProduct ncbigene:292310
Ffar3 GeneProduct ncbigene:365228
Mchr1 GeneProduct ncbigene:83567
RGD1563245 GeneProduct ncbigene:289180
Ptafr GeneProduct ncbigene:58949
GALR1 GeneProduct ncbigene:50577
Agtr1a GeneProduct ncbigene:24180
Chrm4 GeneProduct ncbigene:25111
Olr1662 GeneProduct ncbigene:291361
Ptger2 GeneProduct ncbigene:81752
Olr1750 GeneProduct ncbigene:294204
Oxtr GeneProduct ncbigene:25342
Olr464 GeneProduct ncbigene:295734
Hcrtr2 GeneProduct ncbigene:25605
Gpr37 GeneProduct ncbigene:117549
Gpr173 GeneProduct ncbigene:64021
Adra1b GeneProduct ncbigene:24173
Gpr34 GeneProduct ncbigene:554353
Gpr50 GeneProduct ncbigene:117097
Lhcgr GeneProduct ncbigene:25477
P2ry1 GeneProduct ncbigene:25265
Htr5a GeneProduct ncbigene:25689
Olr227 GeneProduct ncbigene:293370
Adrb1 GeneProduct ncbigene:24925
Gpr68 GeneProduct ncbigene:314386
Htr6 GeneProduct ncbigene:64354
Ptger3 GeneProduct ncbigene:24929
Ltb4r GeneProduct ncbigene:59264
NPY1R GeneProduct ncbigene:29358
Olr226 GeneProduct ncbigene:65140
Gpr65 GeneProduct ncbigene:299242
Gpr35 GeneProduct ncbigene:367315
Gpr1 GeneProduct ncbigene:25457
P2ry13 GeneProduct ncbigene:310444
Olr1693 GeneProduct ncbigene:365523
Ccr3 GeneProduct ncbigene:117027
Grpr GeneProduct ncbigene:24938
Htr1a GeneProduct ncbigene:24473
Olr808 GeneProduct ncbigene:405140
Il8rb GeneProduct ncbigene:29385
Olr1654 GeneProduct ncbigene:60451
Gpr174 GeneProduct ncbigene:302373
Drd3 GeneProduct ncbigene:29238
Npffr2 GeneProduct ncbigene:78964
Olr1329 GeneProduct ncbigene:405075
Gpr63 GeneProduct ncbigene:297952
Ptgir GeneProduct ncbigene:292661
Opn3 GeneProduct ncbigene:498289
Npbwr1 GeneProduct ncbigene:297795
Prlhr GeneProduct ncbigene:246075
Gpr45 GeneProduct ncbigene:301372
Ccrl2 GeneProduct ncbigene:316019
Opn1sw GeneProduct ncbigene:81644
Gpr81 GeneProduct ncbigene:689936
Olr1512 GeneProduct ncbigene:287511
Ccr6 GeneProduct ncbigene:308163
Fshr GeneProduct ncbigene:25449
GPR77 GeneProduct ncbigene:445269
Avpr1b GeneProduct ncbigene:29462
Il8ra GeneProduct ncbigene:54258
P2ry14 GeneProduct ncbigene:171108
Gpr3 GeneProduct ncbigene:266769
Olr1579 GeneProduct ncbigene:289239
Fpr3 GeneProduct ncbigene:292413
Oprd1 GeneProduct ncbigene:24613
Hrh3 GeneProduct ncbigene:85268
Gpr44 GeneProduct ncbigene:309212
Lpar4 GeneProduct ncbigene:302378
Adora2b GeneProduct ncbigene:29316
F2rl2 GeneProduct ncbigene:29636
Olr1671 GeneProduct ncbigene:294138
Olr588 GeneProduct ncbigene:295822
Ffar1 GeneProduct ncbigene:266607
Ccbp2 GeneProduct ncbigene:140473
Cckbr GeneProduct ncbigene:25706
Npy5r GeneProduct ncbigene:25340
Adrb3 GeneProduct ncbigene:25645
Adra1a GeneProduct ncbigene:29412
Cxcr7 GeneProduct ncbigene:84348
Ffar2 GeneProduct ncbigene:292794
Olr1077 GeneProduct ncbigene:405280
Gpr87 GeneProduct ncbigene:310443
Galr3 GeneProduct ncbigene:29235
Htr2a GeneProduct ncbigene:29595
Chrm3 GeneProduct ncbigene:24260
Brs3 GeneProduct ncbigene:260319
Ednra GeneProduct ncbigene:24326
Olr1517 GeneProduct ncbigene:287516
CCR2 GeneProduct ncbigene:60463
Olr1606 GeneProduct ncbigene:305711
Aplnr GeneProduct ncbigene:83518
Mc2r GeneProduct ncbigene:282839
Drd5 GeneProduct ncbigene:25195
Gpr21 GeneProduct ncbigene:689917
P2ry5 GeneProduct ncbigene:691774
Tbxa2r GeneProduct ncbigene:24816
Adrb2 GeneProduct ncbigene:24176
Adra1d GeneProduct ncbigene:29413
Sucnr1 GeneProduct ncbigene:408199
Mc3r GeneProduct ncbigene:29310
PTGDR GeneProduct ncbigene:498475
Cysltr1 GeneProduct ncbigene:114099
Gper GeneProduct ncbigene:171104
Gpr4 GeneProduct ncbigene:308408
Adra2b GeneProduct ncbigene:24174
Gpr20 GeneProduct ncbigene:60667
Ccr1 GeneProduct ncbigene:57301
Ntsr1 GeneProduct ncbigene:366274
Agtr2 GeneProduct ncbigene:24182
C3ar1 GeneProduct ncbigene:84007
Mc4r GeneProduct ncbigene:25635
Avpr2 GeneProduct ncbigene:25108
Gpr27 GeneProduct ncbigene:65275
Chrm1 GeneProduct ncbigene:25229
Hrh1 GeneProduct ncbigene:24448
Ppyr1 GeneProduct ncbigene:29471
Avpr1a GeneProduct ncbigene:25107
Ccr10 GeneProduct ncbigene:363682
Ghsr GeneProduct ncbigene:84022
Olr217 GeneProduct ncbigene:293364
Olr806 GeneProduct ncbigene:405331
Npffr1 GeneProduct ncbigene:64107
Htr7 GeneProduct ncbigene:65032
Hrh2 GeneProduct ncbigene:25461
P2ry12 GeneProduct ncbigene:64803
Htr2c GeneProduct ncbigene:25187
Gpr171 GeneProduct ncbigene:688737
Olr420 GeneProduct ncbigene:296682
Mas1 GeneProduct ncbigene:25153
Mc5r GeneProduct ncbigene:25726
Drd1a GeneProduct ncbigene:24316
Gpr18 GeneProduct ncbigene:679957
Cckar GeneProduct ncbigene:24889
Opn1mw GeneProduct ncbigene:89810
Ednrb GeneProduct ncbigene:50672
Bdkrb1 GeneProduct ncbigene:81509
Olr1743 GeneProduct ncbigene:294197
Olr1466 GeneProduct ncbigene:287480
Bdkrb2 GeneProduct ncbigene:25245
Olr1356 GeneProduct ncbigene:302954
Gpr83 GeneProduct ncbigene:140595
Npy2r GeneProduct ncbigene:66024
Sstr3 GeneProduct ncbigene:171044
Htr1d GeneProduct ncbigene:25323
Olr811 GeneProduct ncbigene:405138
Cxcr4 GeneProduct ncbigene:60628
Gpr75 GeneProduct ncbigene:498434
Ccr5 GeneProduct ncbigene:117029
Gpcr12 GeneProduct ncbigene:80840
Ccr7 GeneProduct ncbigene:287673
Gpr25 GeneProduct ncbigene:363993
Ccr9 GeneProduct ncbigene:282832
Olr1749 GeneProduct ncbigene:294203
Olr1087 GeneProduct ncbigene:299586
Chrm5 GeneProduct ncbigene:53949