Cell migration and invasion through p75NTR (WP4561)

Homo sapiens

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p75NTR or NGFR (HGNC symbol) is an important factor regulating neuronal crest development and plays an important role in invasion and migration of neuronal cells during embryonic development.

Authors

Friederike Ehrhart , Denise Slenter , and Kristina Hanspers

Activity

last edited

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Organisms

Homo sapiens

Communities

Annotations

Participants
Query Drugst.One

Label Type Compact Identifier Comment
EFNB2 GeneProduct ensembl:ENSG00000125266
TIAM1 GeneProduct ensembl:ENSG00000156299
STAT3 GeneProduct ncbigene:6774 STAT3
MMP8 GeneProduct ensembl:ENSG00000118113
TRIO GeneProduct ensembl:ENSG00000038382
EFNA5 GeneProduct ensembl:ENSG00000184349
MMP2 GeneProduct ensembl:ENSG00000087245
MMP9 GeneProduct ensembl:ENSG00000100985
NGFR GeneProduct ensembl:ENSG00000064300 p75NTR
EFNB3 GeneProduct ensembl:ENSG00000108947
TWIST1 GeneProduct ensembl:ENSG00000122691
ARF1 GeneProduct ensembl:ENSG00000143761
EFNA2 GeneProduct ensembl:ENSG00000099617
EFNA4 GeneProduct ensembl:ENSG00000243364
EFNA1 GeneProduct ensembl:ENSG00000169242
EFNA3 GeneProduct ensembl:ENSG00000143590
TWIST1 GeneProduct ensembl:ENSG00000122691
EFNB1 GeneProduct ensembl:ENSG00000090776
BDNF GeneProduct ncbigene:627 BDNF
PARD3 GeneProduct ensembl:ENSG00000148498
RAC1 GeneProduct ensembl:ENSG00000136238
KIDINS220 GeneProduct ensembl:ENSG00000134313
JUN GeneProduct ensembl:ENSG00000177606
NTRK2 GeneProduct ensembl:ENSG00000148053
ADAMTS13 GeneProduct ensembl:ENSG00000160323 ADAM13
PAK1 GeneProduct ensembl:ENSG00000149269
RHOA GeneProduct ncbigene:387 RhoA
AKT2 GeneProduct ensembl:ENSG00000105221
AKT1 GeneProduct ensembl:ENSG00000142208
EFNB2 GeneProduct ensembl:ENSG00000125266
EFNB3 GeneProduct ensembl:ENSG00000108947
EFNB1 GeneProduct ensembl:ENSG00000090776
STAT3 GeneProduct ncbigene:6774 STAT3
STAT3 GeneProduct ncbigene:6774 STAT3
MMP2 GeneProduct ensembl:ENSG00000087245
MMP9 GeneProduct ensembl:ENSG00000100985
CDH11 GeneProduct ncbigene:1009 Cadherin
RAC1 GeneProduct ensembl:ENSG00000136238
RAC1 GeneProduct ensembl:ENSG00000136238
NGFR GeneProduct ensembl:ENSG00000064300 p75NTR
NTRK2 GeneProduct ensembl:ENSG00000148053
BDNF GeneProduct ncbigene:627 BDNF
AKT3 GeneProduct ensembl:ENSG00000117020
AKT2 GeneProduct ensembl:ENSG00000105221
AKT1 GeneProduct ensembl:ENSG00000142208
AKT3 GeneProduct ensembl:ENSG00000117020
CDH11 GeneProduct ncbigene:1009 Cadherin

References

  1. From Neural Crest Development to Cancer and Vice Versa: How p75NTR and (Pro)neurotrophins Could Act on Cell Migration and Invasion? Wislet S, Vandervelden G, Rogister B. Front Mol Neurosci. 2018 Aug 23;11:244. PubMed Europe PMC Scholia