Protein alkylation leading to liver fibrosis (WP3980)

Homo sapiens

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Protein alkylation leading to liver fibrosis This pathway is based on descriptive text of the adverse outcome pathway (AOP) on https://aopwiki.org/aops/38

Authors

Marvin Martens and Egon Willighagen

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

Adverse Outcome Pathways

Annotations

Pathway Ontology

liver disease pathway

Disease Ontology

liver disease

Participants

Label Type Compact URI Comment
thioacetamide Metabolite wikidata:Q416253
Dimethylnitrosamine Metabolite chebi:35807
allyl alcohol Metabolite chebi:16605
retinol Metabolite chebi:50211
CCl4 Metabolite chebi:27385

References

  1. Adverse outcome pathway development from protein alkylation to liver fibrosis. Horvat T, Landesmann B, Lostia A, Vinken M, Munn S, Whelan M. Arch Toxicol. 2017 Apr;91(4):1523–43. PubMed Europe PMC Scholia