ID signaling pathway (WP397)

Rattus norvegicus

Inhibitor of DNA binding (ID) proteins are members of the helix-loop-helix (HLH) family of proteins which lack a DNA binding domain themselves but bind to other family members inhibiting their DNA binding capacity. This family of proteins is comprised of IDs 1, 2, 3 and 4. They can be stimulated by ligands such as the Vascular Endothelial Growth Factor (VEGF), TGF beta and the T cell receptor. Source: NetPath


Akhilesh Pandey , Alex Pico , Christine Chichester , and Eric Weitz


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Rattus norvegicus



Pathway Ontology

Inhibitor of DNA binding signaling pathway


Label Type Compact URI Comment
Id1 GeneProduct ncbigene:25261
Id2 GeneProduct ncbigene:25587
Id3 GeneProduct ncbigene:25585
Id4 GeneProduct ncbigene:291023
Id2 GeneProduct ncbigene:25587
Rb1 GeneProduct ncbigene:24708
Rbl2 GeneProduct ncbigene:81758
Rbl1 GeneProduct ncbigene:680111
Tcfe2a GeneProduct ncbigene:171046
Myod1 GeneProduct ncbigene:337868
Cdk2 GeneProduct ncbigene:362817
Ccna2 GeneProduct ncbigene:114494
Ccne1 GeneProduct ncbigene:25729
Elk1 GeneProduct ncbigene:314436
Elk4 GeneProduct ncbigene:304786
Elk3 GeneProduct ncbigene:362871
Psmd4 GeneProduct ncbigene:83499
Hes1 GeneProduct ncbigene:29577
Pax2 GeneProduct ncbigene:293992
Pax8 GeneProduct ncbigene:81819
Myf5 GeneProduct ncbigene:299766
Myf6 GeneProduct ncbigene:25714
Myog GeneProduct ncbigene:29148
Tcf12 GeneProduct ncbigene:25720
Srebf1 GeneProduct ncbigene:78968
Msc GeneProduct ncbigene:312897
Bmp2 GeneProduct ncbigene:29373
Bmpr2 GeneProduct ncbigene:140590
Vegfa GeneProduct ncbigene:83785
Flt1 GeneProduct ncbigene:54251
KDR GeneProduct ncbigene:25589
Smad1 GeneProduct ncbigene:25671
Smad4 GeneProduct ncbigene:50554
Smad5 GeneProduct ncbigene:59328
Atf3 GeneProduct ncbigene:25389
Smad3 GeneProduct ncbigene:25631
Tgif1 GeneProduct ncbigene:316742
Acvrl1 GeneProduct ncbigene:25237
Smad4 GeneProduct ncbigene:50554
Smad5 GeneProduct ncbigene:59328
Smad1 GeneProduct ncbigene:25671
LCK GeneProduct ncbigene:313050
Igf1r GeneProduct ncbigene:25718
Igf1 GeneProduct ncbigene:24482
Irs1 GeneProduct ncbigene:25467
Ctnnb1 GeneProduct ncbigene:84353
Tert GeneProduct ncbigene:301965
Nfkb1 GeneProduct ncbigene:81736
Rela GeneProduct ncbigene:309165
Bmp6 GeneProduct ncbigene:25644
Cd40lg GeneProduct ncbigene:84349
Ngf GeneProduct ncbigene:310738
Atf3 GeneProduct ncbigene:25389
Smad3 GeneProduct ncbigene:25631
Egf GeneProduct ncbigene:25313
LOC679869 GeneProduct ncbigene:679869