Caffeine and theobromine metabolism (WP3633)

Homo sapiens

Open in new tab Open in NDEx
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
Metabolism pathway of two compounds commonly found in human samples: caffeine and theobromine.

Authors

Egon Willighagen , Denise Slenter , Eric Weitz , and Marvin Martens

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

caffeine metabolic pathway xenobiotic metabolic pathway

Participants
Query Drugst.One

Label Type Compact URI Comment
theobromine Metabolite hmdb:HMDB0002825
Xanthine Metabolite hmdb:HMDB0000292
AFMU Metabolite chebi:32643
1-methyluric acid Metabolite hmdb:HMDB0003099
3,7-dimethyluric acid Metabolite hmdb:HMDB0001982
caffeine Metabolite hmdb:HMDB0001847
paraxanthine Metabolite hmdb:HMDB0001860
1-methylxanthine Metabolite hmdb:HMDB0010738
1,7-dimethyluric acid Metabolite hmdb:HMDB0011103
7-methylxanthine Metabolite hmdb:HMDB0001991
7-methyluric acid Metabolite hmdb:HMDB0011107
CYP1A2 GeneProduct ensembl:ENSG00000140505
XDH GeneProduct ensembl:ENSG00000158125
CYP1A2 GeneProduct ensembl:ENSG00000140505
NAT2 GeneProduct ensembl:ENSG00000156006
XDH GeneProduct ensembl:ENSG00000158125 Generally: EC 1.17.3.2
CYP1A2 GeneProduct ensembl:ENSG00000140505
CYP2A6 GeneProduct ensembl:ENSG00000255974
XDH GeneProduct ensembl:ENSG00000158125

References

  1. Variability in caffeine metabolism. Grant DM, Tang BK, Kalow W. Clin Pharmacol Ther. 1983 May;33(5):591–602. PubMed Europe PMC Scholia