Fatty acid biosynthesis (WP336)

Mus musculus

The production of fatty acids from acetyl-CoA and NADPH through the use of enzymes known as fatty acid synthases is referred to as fatty acid synthesis. This biological process occurs within the cytoplasm of cells. The majority of acetyl-CoA that is transformed into fatty acids originates from carbohydrates through the glycolytic pathway.


Kdahlquist , Chris Evelo , JT. Saito , Christine Chichester , Martina Summer-Kutmon , Eric Weitz , Egon Willighagen , and Alex Pico


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Mus musculus



Pathway Ontology

fatty acid biosynthetic pathway


Label Type Compact URI Comment
Malonyl-CoA Metabolite hmdb:HMDB0001175
Acetyl-CoA Metabolite hmdb:HMDB0001206
Fasn GeneProduct ncbigene:14104
Echs1 GeneProduct ncbigene:93747
Acsl5 GeneProduct ncbigene:433256
Fasn GeneProduct ncbigene:14104
Pecr GeneProduct ncbigene:111175
Echdc2 GeneProduct ncbigene:52430
Acaca GeneProduct ncbigene:107476
Echdc1 GeneProduct ncbigene:52665
Acsl4 GeneProduct ncbigene:50790
Fasn GeneProduct ncbigene:14104
Scd1 GeneProduct ncbigene:20249
Acss2 GeneProduct ncbigene:60525
Fasn GeneProduct ncbigene:14104
Echdc3 GeneProduct ncbigene:67856
Fasn GeneProduct ncbigene:14104
Acly GeneProduct ncbigene:104112
Fasn GeneProduct ncbigene:14104
Acsl3 GeneProduct ncbigene:74205
Hadh GeneProduct ncbigene:15107
Fasn GeneProduct ncbigene:14104
Acacb GeneProduct ncbigene:100705
Acsl1 GeneProduct ncbigene:14081
Pcx GeneProduct ncbigene:18563
Acaa2 GeneProduct ncbigene:52538
Fasn GeneProduct ncbigene:14104
Mecr GeneProduct ncbigene:26922
Decr1 GeneProduct ncbigene:67460
Acsl6 GeneProduct ncbigene:216739
Ech1 GeneProduct ncbigene:51798