Drug induction of bile acid pathway (WP3253)
Bos taurus
Authors
Martina Summer-Kutmon , Susan Coort , Eric Weitz , and Egon WillighagenActivity
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Organisms
Bos taurusCommunities
Annotations
Pathway Ontology
drug pathway bile acid signaling pathwayCell Type Ontology
hepatocyte| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Chlorpromazine | Metabolite | pubchem.compound:2726 | |
| Bile acids | Metabolite | chebi:3098 | |
| Ezetimibe | Metabolite | pubchem.compound:150311 | |
| Troglitazone | Metabolite | pubchem.compound:5591 | |
| Cholesterol | Metabolite | hmdb:HMDB0000067 | |
| Tetrahydrocortisone | Metabolite | hmdb:HMDB0000903 | |
| Cyclosporin | Metabolite | pubchem.compound:5284373 | |
| Glycocholic acid | Metabolite | hmdb:HMDB0000138 | |
| Clozapine | Metabolite | pubchem.compound:135398737 | |
| Taurocholic acid | Metabolite | hmdb:HMDB0000036 | |
| Bilirubin | Metabolite | hmdb:HMDB0000054 | |
| Isoursodeoxycholic acid | Metabolite | hmdb:HMDB0000686 | |
| Deoxycholic acid | Metabolite | hmdb:HMDB0000626 | |
| Methylprednisolone | Metabolite | pubchem.compound:6741 | |
| Cimetidine | Metabolite | pubchem.compound:2756 | |
| Phospholipids | Metabolite | chebi:16247 | |
| Digoxin | Metabolite | hmdb:HMDB0001917 | |
| Clarithromyci | Metabolite | pubchem.compound:84029 | |
| Erythromycin | Metabolite | pubchem.compound:12560 | |
| Silybin | Metabolite | pubchem.compound:31553 | |
| Glyburide | Metabolite | pubchem.compound:3488 | |
| Tacrolimus | Metabolite | pubchem.compound:445643 | |
| Trabectedin | Metabolite | pubchem.compound:108150 | |
| Phomin | Metabolite | pubchem.compound:5311281 | |
| Colchicine | Metabolite | pubchem.compound:6167 | |
| Ranitidine | Metabolite | hmdb:HMDB0001930 | |
| Oxiglutatione | Metabolite | pubchem.compound:65359 | |
| SLCO1B1 | GeneProduct | ensembl:ENSBTAG00000022329 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10599 |
| SULT2A1 | GeneProduct | ensembl:ENSBTAG00000039971 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6822 |
| CYP3A4 | GeneProduct | ensembl:ENSBTAG00000047379 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1576 |
| SLC10A1 | GeneProduct | ensembl:ENSBTAG00000001881 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6554 |
| CYP7A1 | GeneProduct | ensembl:ENSBTAG00000005287 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1581 |
| BAAT | GeneProduct | ensembl:ENSBTAG00000025760 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:570 |
| ABCB1 | GeneProduct | ensembl:ENSBTAG00000005997 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5243 |
| NR1H4 | GeneProduct | ensembl:ENSBTAG00000013596 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9971 |
| SLC51A | GeneProduct | ensembl:ENSBTAG00000012347 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:200931 |
| VDR | GeneProduct | ensembl:ENSBTAG00000016414 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7421 |
| NR1I3 | GeneProduct | ensembl:ENSBTAG00000009215 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9970 |
| NR1I2 | GeneProduct | ensembl:ENSBTAG00000019557 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8856 |
| SLC51B | GeneProduct | ensembl:ENSBTAG00000003737 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:123264 |
| ABCC4 | GeneProduct | ensembl:ENSBTAG00000046611 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10257 |
| ABCB11 | GeneProduct | ensembl:ENSBTAG00000026885 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8647 |