Synaptic vesicle pathway (WP3224)

Bos taurus

Pathway depicting synaptic transmission of neurotransmitters from the presynaptic nerve terminal to the synaptic cleft upon depolarization. Synaptotagmin mediated transport along the nerve cell cytoskeleton indicates the initial step of this process. Originally created by Joanna S. Fong and Nathan Salomonis in the Bruce Conklin laboratory 5/12/2000 for use in GenMAPP. Genes associated with neurotransmitter reuptake from the synaptic left were obtained from the Gene Ontology term GO:0001504. For additional information see: http://en.wikipedia.org/wiki/Synaptic_vesicle

Authors

Martina Summer-Kutmon and Eric Weitz

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

synaptic vesicle cycle pathway

Participants

Label Type Compact URI Comment
L-Glutamine Metabolite hmdb:HMDB0000641
Dopamine Metabolite hmdb:HMDB0000073
Serotonin Metabolite hmdb:HMDB0000259
SYN1 GeneProduct ensembl:ENSBTAG00000005042 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000008056
RAB3A GeneProduct ensembl:ENSBTAG00000010635 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105649
SYN2 GeneProduct ensembl:ENSBTAG00000020260 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000157152
SYN3 GeneProduct ensembl:ENSBTAG00000020636 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000185666
SYT1 GeneProduct ensembl:ENSBTAG00000034693 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000067715
VAMP2 GeneProduct ensembl:ENSBTAG00000003891 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000220205
STX1B GeneProduct ensembl:ENSBTAG00000002349 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000099365
STX2 GeneProduct ensembl:ENSBTAG00000007988 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000111450
STX1A GeneProduct ensembl:ENSBTAG00000017075 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000106089
STX3 GeneProduct ensembl:ENSBTAG00000012820 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000166900
SNAP25 GeneProduct ensembl:ENSBTAG00000008323 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000132639
RIMS1 GeneProduct ensembl:ENSBTAG00000020238 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000079841
STXBP1 GeneProduct ensembl:ENSBTAG00000003525 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000136854
UNC13C GeneProduct ensembl:ENSBTAG00000025522 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000137766
UNC13B GeneProduct ensembl:ENSBTAG00000011397 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000198722
UNC13A GeneProduct ensembl:ENSBTAG00000012682 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000130477
CPLX3 GeneProduct ensembl:ENSBTAG00000021426 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000213578
CPLX2 GeneProduct ensembl:ENSBTAG00000013741 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000145920
NAPA GeneProduct ensembl:ENSBTAG00000013084 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105402
NSF GeneProduct ensembl:ENSBTAG00000008442 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000073969
CACNA1A GeneProduct ensembl:ENSBTAG00000014828 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000141837
CACNA1B GeneProduct ensembl:ENSBTAG00000007882 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000148408
SYP GeneProduct ensembl:ENSBTAG00000016096 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000102003
DNM1 GeneProduct ensembl:ENSBTAG00000011307 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000106976
DNM1L GeneProduct ensembl:ENSBTAG00000011395 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000087470
DNM2 GeneProduct ensembl:ENSBTAG00000013362 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000079805
DNM3 GeneProduct ensembl:ENSBTAG00000014319 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197959
CLTA GeneProduct ensembl:ENSBTAG00000001137 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000122705
CLTC GeneProduct ensembl:ENSBTAG00000016708 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000141367
AP2S1 GeneProduct ensembl:ENSBTAG00000010584 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000042753
AP2A1 GeneProduct ensembl:ENSBTAG00000019180 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000196961
AP2A2 GeneProduct ensembl:ENSBTAG00000009915 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000183020
AP2B1 GeneProduct ensembl:ENSBTAG00000020316 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000006125
AP2M1 GeneProduct ensembl:ENSBTAG00000020106 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000161203
SLC32A1 GeneProduct ensembl:ENSBTAG00000047894 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000101438
SLC17A8 GeneProduct ensembl:ENSBTAG00000001088 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000179520
SLC17A7 GeneProduct ensembl:ENSBTAG00000007036 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000104888
SLC17A6 GeneProduct ensembl:ENSBTAG00000038347 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000091664
SLC18A1 GeneProduct ensembl:ENSBTAG00000020788 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000036565
SLC18A2 GeneProduct ensembl:ENSBTAG00000004739 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000165646
SLC18A3 GeneProduct ensembl:ENSBTAG00000014990 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000187714
SLC22A3 GeneProduct ensembl:ENSBTAG00000039080 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000146477
SLC38A1 GeneProduct ensembl:ENSBTAG00000000859 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000111371
PARK7 GeneProduct ensembl:ENSBTAG00000020518 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116288
SLC1A3 GeneProduct ensembl:ENSBTAG00000018245 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000079215
CLN8 GeneProduct ensembl:ENSBTAG00000008584 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000182372
SLC6A4 GeneProduct ensembl:ENSBTAG00000019349 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000108576
SLC25A4 GeneProduct ensembl:ENSBTAG00000013208 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000151729
ATP1A2 GeneProduct ensembl:ENSBTAG00000010551 HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000018625

References