Quercetin and Nf-kB / AP-1 induced cell apoptosis (WP3167)
Bos taurus
Authors
Martina Summer-Kutmon , Linda Rieswijk , Eric Weitz , and Lars WillighagenActivity
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Organisms
Bos taurusCommunities
Annotations
Pathway Ontology
apoptotic cell death pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Prostaglandin G2 | Metabolite | hmdb:HMDB0003235 | |
| Quercetin | Metabolite | hmdb:HMDB0005794 | |
| Prostaglandin H2 | Metabolite | hmdb:HMDB0001381 | |
| Arachidonic acid | Metabolite | hmdb:HMDB0001043 | |
| Prostaglandin I2 | Metabolite | hmdb:HMDB0001335 | |
| Thromboxane A2 | Metabolite | hmdb:HMDB0001452 | |
| Prostaglandin F2a | Metabolite | hmdb:HMDB0001139 | |
| Prostaglandin D2 | Metabolite | hmdb:HMDB0001403 | |
| Prostaglandin E2 | Metabolite | hmdb:HMDB0001220 | |
| COX1 | GeneProduct | ensembl:ENSBTAG00000043561 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4512 |
| IKBKB | GeneProduct | ensembl:ENSBTAG00000007599 | Type your comment hereHomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000104365 |
| NFKB1 | GeneProduct | ensembl:ENSBTAG00000020270 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000109320 |
| MAFK | GeneProduct | ensembl:ENSBTAG00000019303 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7975 |
| MAFG | GeneProduct | ensembl:ENSBTAG00000000040 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4097 |
| ACOX2 | GeneProduct | ensembl:ENSBTAG00000004178 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000168306 |
| FOS | GeneProduct | ensembl:ENSBTAG00000004322 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000170345 |
| NOS1 | GeneProduct | ensembl:ENSBTAG00000002023 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000089250 |
| VEGFA | GeneProduct | ensembl:ENSBTAG00000047561 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000112715 |
| NFKB1 | GeneProduct | ensembl:ENSBTAG00000020270 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000109320 |
| JUN | GeneProduct | ensembl:ENSBTAG00000004037 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000177606 |
| MMP1 | GeneProduct | ensembl:ENSBTAG00000048029 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000196611 |
| CYP2A6 | GeneProduct | ensembl:ENSBTAG00000047815 | one of several possible phase 1 enzymesHomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000255974 |
| NFE2L2 | GeneProduct | ensembl:ENSBTAG00000019255 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116044 |
| KEAP1 | GeneProduct | ensembl:ENSBTAG00000003543 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000079999 |
| NFE2L2 | GeneProduct | ensembl:ENSBTAG00000019255 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116044 |
| NFE2L2 | GeneProduct | ensembl:ENSBTAG00000019255 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116044 |
| PGHS-2 | GeneProduct | ensembl:ENSBTAG00000014127 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5743 |
| BIKBA | Protein | ensembl:ENSBTAG00000016683 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P25963 |
| BIKBA | Protein | ensembl:ENSBTAG00000016683 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = S:P25963 |
References
- The role of phytochemicals in inhibition of cancer and inflammation: New directions and perspectives. Issa AY, Volate SR, Wargovich MJ. Journal of Food Composition and Analysis [Internet]. 2006 Aug;19(5):405–19. Available from: http://dx.doi.org/10.1016/j.jfca.2006.02.009 DOI Scholia
- Prostaglandins and leukotrienes: advances in eicosanoid biology. Funk CD. Science. 2001 Nov 30;294(5548):1871–5. PubMed Europe PMC Scholia
- Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin. Tanigawa S, Fujii M, Hou DX. Free Radic Biol Med. 2007 Jun 1;42(11):1690–703. PubMed Europe PMC Scholia
- Prostaglandins and inflammation. Ricciotti E, FitzGerald GA. Arterioscler Thromb Vasc Biol. 2011 May;31(5):986–1000. PubMed Europe PMC Scholia