Starch and cellulose biosynthesis (WP257)

Saccharomyces cerevisiae

In addition to being a common source of energy among most organisms, glucose is also a precursor to starch and cellulose biosynthesis. The production of ADP-, GDP-, and UDP-D-glucose stems from glucose-1-phosphate, which is converted from the common glucose derivative, glucose-6-phosphate.


Meredith Braymer , Daniela Digles , Egon Willighagen , Alex Pico , Denise Slenter , and Eric Weitz


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Saccharomyces cerevisiae



Pathway Ontology

starch and cellulose biosynthetic pathway


Label Type Compact URI Comment
UDP-D-glucose Metabolite chebi:46229
1,4-alpha-D-glucan (n+1) Metabolite chebi:28102
1,4-alpha-D-Glucan Metabolite chebi:28102
UDP-D-glucuronate Metabolite chebi:17200
GDP-D-glucose Metabolite wikidata:Q27102347
(1,4-beta-D-Glucosyl)n Metabolite chebi:18246
ADP-D-glucose Metabolite chebi:15751
(1,4-beta-D-glucosyl)n Metabolite chebi:18246
glucose-6-phosphate Metabolite chebi:75150
NADH Metabolite cas:53-84-9
GDP Metabolite cas:146-91-8
pyrophosphate Metabolite cas:2466-09-3
maltose Metabolite cas:69-79-4
pyrophosphate Metabolite cas:2466-09-3
ATP Metabolite cas:1927-31-7
GTP Metabolite cas:2564-35-4
ADP Metabolite cas:58-64-0
pyrophosphate Metabolite cas:2466-09-3
glucose-1-phosphate Metabolite chebi:16077
UTP Metabolite chebi:46398
NAD Metabolite chebi:13389
H2O Metabolite chebi:15377
H2O Metabolite chebi:15377
PGM2 GeneProduct sgd:S000004711
GLC3 GeneProduct sgd:S000000737
UGP1 GeneProduct sgd:S000001518
YHL012W GeneProduct sgd:S000001004
PGM1 GeneProduct sgd:S000001610


  1. Genetic and biochemical characterization of the UGP1 gene encoding the UDP-glucose pyrophosphorylase from Saccharomyces cerevisiae. Daran JM, Dallies N, Thines-Sempoux D, Paquet V, François J. Eur J Biochem. 1995 Oct 15;233(2):520–30. PubMed Europe PMC Scholia