Serotonin and anxiety (WP2132)
Rattus norvegicus
Authors
Helix , Andra Waagmeester , Egon Willighagen , and Linda RieswijkActivity
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Cited In
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Organisms
Rattus norvegicusCommunities
Annotations
Pathway Ontology
disease pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| THDOC | Metabolite | pubchem.compound:91475 | |
| ketanserin | Metabolite | chebi:6123 | |
| Adra1a | GeneProduct | ensembl:ENSRNOG00000009522 | |
| Grin2d | GeneProduct | ensembl:ENSRNOG00000021063 | |
| Htr2a | GeneProduct | ensembl:ENSRNOG00000010063 | |
| Arc | GeneProduct | ensembl:ENSRNOG00000043465 | |
| Nlgn1 | GeneProduct | ensembl:ENSRNOG00000032576 | |
| Plek | GeneProduct | ensembl:ENSRNOG00000005214 | |
| Ppp3ca | GeneProduct | ensembl:ENSRNOG00000009882 | |
| Plcd4 | GeneProduct | ensembl:ENSRNOG00000016361 | |
| Htr1a | GeneProduct | ensembl:ENSRNOG00000010254 | |
| Htr2c | GeneProduct | ensembl:ENSRNOG00000030877 | |
| KPCB | GeneProduct | ensembl:ENSRNOG00000012061 | |
| Fos | GeneProduct | ensembl:ENSRNOG00000008015 | |
| CRF | Protein | uniprot:P01143 |
References
- Postnatal serotonin type 2 receptor blockade prevents the emergence of anxiety behavior, dysregulated stress-induced immediate early gene responses, and specific transcriptional changes that arise following early life stress. Benekareddy M, Vadodaria KC, Nair AR, Vaidya VA. Biol Psychiatry. 2011 Dec 1;70(11):1024–32. PubMed Europe PMC Scholia