Splicing factor NOVA regulated synaptic proteins (WP1983)

Mus musculus

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Synaptic Communication influenced by NOVA-splicing regulation

Authors

Bahar Taneri , Martina Summer-Kutmon , Daniela Digles , and Egon Willighagen

Activity

last edited

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Cited In

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Organisms

Mus musculus

Communities

Annotations

Pathway Ontology

cadherin mediated signaling pathway

Participants

Label Type Compact URI Comment
PIP2 Metabolite hmdb:HMDB0010032
PIP2 Metabolite hmdb:HMDB0010032
Cav2.2 GeneProduct ensembl:ENSMUSG00000000058 Validated target - predicted by splicing microarray
4.1G GeneProduct ncbigene:13822 Validated target - predicted by splicing microarray
NIK/Mapk4 GeneProduct ensembl:ENSMUSG00000024558 Validated target - predicted by splicing microarray
N-Cadherin GeneProduct ncbigene:12558
SKIP GeneProduct ncbigene:66354 Validated target - predicted by splicing microarray
Calsyntenin GeneProduct ncbigene:65945 Validated target - predicted by splicing microarray
GIRK2 GeneProduct ncbigene:16522 CLIP predicted target
Clasp1 GeneProduct ensembl:ENSMUSG00000064302 Validated target - predicted by splicing microarray
Slo GeneProduct ncbigene:16531 Validated target - predicted by splicing microarray
CASK GeneProduct ensembl:ENSMUSG00000031012 Validated target - predicted by splicing microarray
neurochondrin GeneProduct ncbigene:26562 Validated target - predicted by splicing microarray
GABAARg2 GeneProduct ncbigene:14406 Validated target
JNK2 GeneProduct ncbigene:26420 Validated target - predicted by CLIP
PMCA1 GeneProduct ncbigene:67972 Validated target - predicted by splicing microarray
Plcb4 GeneProduct ensembl:ENSMUSG00000039943 Validated target - predicted by splicing microarray
Rap1gap GeneProduct ncbigene:110351 Validated target - predicted by splicing microarray
Syntaxin 2 GeneProduct ncbigene:13852 Validated target - predicted by splicing microarray
Camk2g GeneProduct ensembl:ENSMUSG00000021820 Validated target - predicted by splicing microarray
Igsf4a GeneProduct ncbigene:54725 Validated target - predicted by splicing microarray
Neogenin GeneProduct ncbigene:18007 Validated target - predicted by CLIP
Cav2.2 GeneProduct ensembl:ENSMUSG00000000058 Validated target - predicted by splicing microarray
Cask GeneProduct ensembl:ENSMUSG00000031012 Validated target - predicted by splicing microarray
Gephrin GeneProduct ncbigene:268566 Validated target - predicted by splicing microarray
Dab1 GeneProduct ensembl:ENSMUSG00000028519 Validated target - predicted by bioinformatics
Aplp2 GeneProduct ensembl:ENSMUSG00000031996 Validated target - predicted by splicing microarray
Kcnq2 GeneProduct ensembl:ENSMUSG00000016346 Validated target - predicted by splicing microarray
Munc18 GeneProduct ncbigene:20911 Validated target - predicted by splicing microarray
4.1R GeneProduct ncbigene:269587 Validated target - predicted by splicing microarray
4.1B GeneProduct ncbigene:13823 Validated target - predicted by splicing microarray
Chl1 GeneProduct ensembl:ENSMUSG00000030077 Validated target - predicted by splicing microarray
Netrin G1 GeneProduct ncbigene:80883 Validated target - predicted by splicing microarray
Rap1 GeneProduct ncbigene:57321
EphrinA5 GeneProduct ncbigene:13640 Validated target - predicted by splicing microarray
NMDAR2B GeneProduct ncbigene:14812 CLIP predicted target
NMDAR1 GeneProduct ncbigene:14810 Validated target - predicted by splicing microarray
Chl1 GeneProduct ensembl:ENSMUSG00000030077 Validated target - predicted by splicing microarray
N-Cadherin GeneProduct ncbigene:12558
Ankyrin G GeneProduct ncbigene:11735 Validated target - predicted by splicing microarray
CASK GeneProduct ensembl:ENSMUSG00000031012 Validated target - predicted by splicing microarray
Dab1 GeneProduct ensembl:ENSMUSG00000028519 Validated target - predicted by bioinformatics
GluR6 GeneProduct ncbigene:14806 Validated target - predicted by splicing microarray
Cask GeneProduct ensembl:ENSMUSG00000031012 Validated target - predicted by splicing microarray
PKCz GeneProduct ncbigene:18762 CLIP predicted target
GABAB2R GeneProduct ncbigene:242425 CLIP predicted target
Plcb4 GeneProduct ensembl:ENSMUSG00000039943 Validated target - predicted by splicing microarray
Ankyrin G GeneProduct ncbigene:11735 Validated target - predicted by splicing microarray
Ankyrin G GeneProduct ncbigene:11735 Validated target - predicted by splicing microarray
JNK2 GeneProduct ncbigene:26420 Validated target - predicted by CLIP
4.1R GeneProduct ncbigene:269587 Validated target - predicted by splicing microarray
4.1R GeneProduct ncbigene:269587 Validated target - predicted by splicing microarray
GluR6 GeneProduct ncbigene:14806 Validated target - predicted by splicing microarray
Slo GeneProduct ncbigene:16531 Validated target - predicted by splicing microarray
PKCz GeneProduct ncbigene:18762 CLIP predicted target
GABAB2R GeneProduct ncbigene:242425 CLIP predicted target
Gephrin GeneProduct ncbigene:268566 Validated target - predicted by splicing microarray
Plcb4 GeneProduct ensembl:ENSMUSG00000039943 Validated target - predicted by splicing microarray
4.1N GeneProduct ncbigene:13821 Validated target - predicted by bioinformatics
Igsf4b GeneProduct ncbigene:94332 Validated target - predicted by bioinformatics
MAP4 Protein uniprot:P27546 Validated target - predicted by bioinformatics
AGRIN Protein uniprot:A2ASQ1 Validated target - predicted by splicing microarray
CASK Protein uniprot:P06796 Validated target - predicted by splicing microarray

References

  1. Nova regulates brain-specific splicing to shape the synapse. Ule J, Ule A, Spencer J, Williams A, Hu JS, Cline M, et al. Nat Genet. 2005 Aug;37(8):844–52. PubMed Europe PMC Scholia
  2. An RNA map predicting Nova-dependent splicing regulation. Ule J, Stefani G, Mele A, Ruggiu M, Wang X, Taneri B, et al. Nature. 2006 Nov 30;444(7119):580–6. PubMed Europe PMC Scholia