Mechanisms associated with pluripotency (WP1763)

Mus musculus

The aim of the PluriNetWork is to give an overview of specific mechanisms associated with pluripotency in mouse. Each node represents a gene and its corresponding protein product. As stated, we intentionally focused on information flow, neglecting reactions, metabolites, intracellular movement of components, and their modifications such as protein phosphorylation Each edge can be seen as direct mechanism between its nodes. For more information, see Som A, Harder C, Greber B, Siatkowski M, Paudel Y, et al. 2010 The PluriNetWork: An Electronic Representation of the Network Underlying Pluripotency in Mouse, and Its Applications. PLoS ONE 5(12): e15165. doi:10.1371/journal.pone.0015165 The June 2010 PluriNetWork described in the paper can be found at . The PluriNetWork at WikiPathWays started with the December 2010 version.


C.Harder , Alex Pico , Daniela Digles , Martina Summer-Kutmon , Chris Evelo , Eric Weitz , and Egon Willighagen


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Mus musculus



Pathway Ontology

signaling pathway pertinent to development

Cell Type Ontology

pluripotent stem cell


Label Type Compact URI Comment
Smarcad1 GeneProduct ncbigene:13990 full name: SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
Crebbp GeneProduct ncbigene:12914 full name: CREB binding protein
Rel GeneProduct ncbigene:19696 full name: reticuloendotheliosis oncogene
Ctbp1 GeneProduct ncbigene:13016 full name: C-terminal binding protein 1
Tert GeneProduct ncbigene:21752 full name: telomerase reverse transcriptase
Cdkn2a GeneProduct ncbigene:12578 full name: cyclin-dependent kinase inhibitor 2A
Mdm2 GeneProduct ncbigene:17246 full name: transformed mouse 3T3 cell double minute 2
Cdkn1a GeneProduct ncbigene:12575 full name: cyclin-dependent kinase inhibitor 1A (P21)
Zfp143 GeneProduct ncbigene:20841 full name: zinc finger protein 143
Nr2f2 GeneProduct ncbigene:11819 full name: nuclear receptor subfamily 2, group F, member 2
Nr2f1 GeneProduct ncbigene:13865 full name: nuclear receptor subfamily 2, group F, member 1
Sp1 GeneProduct ncbigene:20683 full name: trans-acting transcription factor 1
Xist GeneProduct ncbigene:213742 full name: inactive X specific transcripts
Mpl GeneProduct ncbigene:17480 full name: myeloproliferative leukemia virus oncogene
Fgf4 GeneProduct ncbigene:14175 full name: fibroblast growth factor 4
Tcfcp2l1 GeneProduct ncbigene:81879 full name: transcription factor CP2-like 1
Mycn GeneProduct ncbigene:18109 full name: v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Bmpr2 GeneProduct ncbigene:12168 full name: bone morphogenic protein receptor, type II (serine/threonine kinase)
Smad4 GeneProduct ncbigene:17128 full name: MAD homolog 4 (Drosophila)
Notch1 GeneProduct ncbigene:18128 full name: Notch gene homolog 1 (Drosophila)
Rras GeneProduct ncbigene:20130 full name: Harvey rat sarcoma oncogene, subgroup R
Wnt5a GeneProduct ncbigene:22418 full name: wingless-related MMTV integration site 5A
Pias2 GeneProduct ncbigene:17344 full name: protein inhibitor of activated STAT 2
Psen1 GeneProduct ncbigene:19164 full name: Presenilin 1
Tpo GeneProduct ncbigene:22018 full name: thyroid peroxidase
Dkk1 GeneProduct ncbigene:13380 full name: dickkopf homolog 1 (Xenopus laevis)
Cer1 GeneProduct ncbigene:12622 full name: cerberus 1 homolog (Xenopus laevis)
Nfkb1 GeneProduct ncbigene:18033 full name: nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
Lefty1 GeneProduct ncbigene:13590 full name: left right determination factor 1
Ptprs GeneProduct ncbigene:19280 full name: protein tyrosine phosphatase, receptor type, S
Fbxo15 GeneProduct ncbigene:50764 full name: F-box protein 15
Cdk2ap1 GeneProduct ncbigene:13445 full name: CDK2 (cyclin-dependent kinase 2)-associated protein 1
Mbd2 GeneProduct ncbigene:17191 full name: methyl-CpG binding domain protein 2
Mbd3 GeneProduct ncbigene:17192 full name: methyl-CpG binding domain protein 3
Ep400 GeneProduct ncbigene:75560 full name: E1A binding protein p400
Ogt GeneProduct ncbigene:108155 full name: O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Ube2i GeneProduct ncbigene:22196 full name: ubiquitin-conjugating enzyme E2I
Med12 GeneProduct ncbigene:59024 full name: mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
Hdac2 GeneProduct ncbigene:15182 full name: Histone deacetylase 2
Trim28 GeneProduct ncbigene:21849 full name: Tripartitemotif-containing28
Yy1 GeneProduct ncbigene:22632 full name: YY1 transcription factor
Arid3b GeneProduct ncbigene:56380 full name: AT rich interactive domain 3B (BRIGHT-like)
Rnf2 GeneProduct ncbigene:19821 full name: ring finger protein 2
Nr5a2 GeneProduct ncbigene:26424 full name: nuclear receptor subfamily 5, group A, member 2
Tcf7 GeneProduct ncbigene:21414 full name: Transcription factor7 ,T-cell specific
Rcor2 GeneProduct ncbigene:104383 full name: REST corepressor 2
Cubn GeneProduct ncbigene:65969 full name: cubilin (intrinsic factor-cobalamin receptor)
Ercc5 GeneProduct ncbigene:22592 full name: excision repair cross-complementing rodent repair deficiency, complementation group 5
Gadd45a GeneProduct ncbigene:13197 full name: growth arrest and DNA-damage-inducible 45 alpha
Nr6a1 GeneProduct ncbigene:328572 full name: nuclear receptor subfamily 6, group A, member 1
Rif1 GeneProduct ncbigene:51869 full name: Rap1 interacting factor 1 homolog (yeast)
Zfp281 GeneProduct ncbigene:226442 full name: zinc finger protein 281
Nacc1 GeneProduct ncbigene:66830 full name: nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
Nr0b1 GeneProduct ncbigene:11614 full name: nuclear receptor subfamily 0, group B, member 1
Zfx GeneProduct ncbigene:22764 full name: zinc finger protein X-linked
Mybl2 GeneProduct ncbigene:17865 full name: myeloblastosis oncogene-like 2
Klf4 GeneProduct ncbigene:16600 full name: Kruppel-like factor 4 (gut)
Dhx9 GeneProduct ncbigene:13211 full name: DEAH (Asp-Glu-Ala-His) box polypeptide 9
Rest GeneProduct ncbigene:19712 full name: RE1-silencing transcription factor
Thap11 GeneProduct ncbigene:59016 full name: THAP domain containing 11
Hcfc1 GeneProduct ncbigene:15161 full name: host cell factor C1
Pou5f1 GeneProduct ncbigene:18999 full name: POU domain, class 5, transcription factor 1
Mapk3 GeneProduct ncbigene:26417 full name: mitogen-activated protein kinase 3
Tcl1 GeneProduct ncbigene:21432 full name: T-cell lymphoma breakpoint 1
Tbx3 GeneProduct ncbigene:21386 full name: T-box3
Id1 GeneProduct ncbigene:15901 full name: inhibitor of DNA binding 1
Gata6 GeneProduct ncbigene:14465 full name: GATA binding protein 6
Pou2f1 GeneProduct ncbigene:18986 full name: POU domain, class 2, transcription factor 1
P4ha1 GeneProduct ncbigene:18451 full name: procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
Gab1 GeneProduct ncbigene:14388 full name: growth factor receptor bound protein 2-associated protein 1
Jak1 GeneProduct ncbigene:16451 full name: Janus kinase 1
Socs1 GeneProduct ncbigene:216233 full name: suppressorofcytokinesignaling2
Il6st GeneProduct ncbigene:16195 full name: interleukin 6 signal transducer
Lifr GeneProduct ncbigene:16880 full name: leukemia inhibitory factor receptor
Lif GeneProduct ncbigene:16878 full name: leukemia inhibitory factor
Apc GeneProduct ncbigene:11789 full name: adenomatosis polyposis coli
Axin1 GeneProduct ncbigene:12005 full name: Axin1
Lef1 GeneProduct ncbigene:16842 full name: lymphoid enhancer binding factor 1
Zic3 GeneProduct ncbigene:22773 full name: zinc finger protein of the cerebellum 3
Trim33 GeneProduct ncbigene:94093 full name: tripartite motif-containing 33
Frap1 GeneProduct ncbigene:56717 full name: FK506 binding protein 12-rapamycin associated protein 1
Akt1 GeneProduct ncbigene:11651 full name: thymoma viral proto-oncogene 1
Myc GeneProduct ncbigene:17869 full name: myelocytomatosis oncogene
Cdx2 GeneProduct ncbigene:12591 full name: caudal type homeo box 2
Ccnd1 GeneProduct ncbigene:12443 full name: cyclin D1
Stat3 GeneProduct ncbigene:20848 full name: signal transducer and activator of transcription 3
Sall4 GeneProduct ncbigene:99377 full name: sal-like 4 (Drosophila)
Foxd3 GeneProduct ncbigene:15221 full name: forkhead box D3
Nanog GeneProduct ncbigene:71950 full name: Nanog homeobox
Sox2 GeneProduct ncbigene:20674 full name: SRY-box containing gene 2
Ddb1 GeneProduct ncbigene:13194 full name: damage specific DNA binding protein 1
Trp53 GeneProduct ncbigene:22059 full name: transformation related protein 53
Eras GeneProduct ncbigene:353283 full name: ES cell-expressed Ras
Pten GeneProduct ncbigene:19211 full name: phosphatase and tensin homolog
Pik3cd GeneProduct ncbigene:18707 full name: phosphatidylinositol 3-kinase, catalytic delta polypeptide
Map2k1 GeneProduct ncbigene:26395 full name: mitogen-activated protein kinase kinase 1
Raf1 GeneProduct ncbigene:110157 full name: v-raf-leukemia viral oncogene 1
Hras1 GeneProduct ncbigene:15461 full name: Harvey rat sarcoma virus oncogene 1
Smad2 GeneProduct ncbigene:17126 full name: MAD homolog 2 (Drosophila)
Tgfbr1 GeneProduct ncbigene:21812 full name: transforming growth factor, beta receptor I / ALK5
Nodal GeneProduct ncbigene:18119 full name: Nodal homolog
Hnrnpu GeneProduct ncbigene:51810 full name: heterogeneous nuclear ribonucleoprotein U
Fgfr1 GeneProduct ncbigene:14182 full name: fibroblast growth factor receptor 1
Bmp4 GeneProduct ncbigene:12159 full name: bone morphogenetic protein 4
Acvr1 GeneProduct ncbigene:11477 full name: activin A receptor, type 1
Smad1 GeneProduct ncbigene:17125 full name: MAD homolog 1 (Drosophila)
Cdh1 GeneProduct ncbigene:12550 full name: cadherin 1
Ctnnb1 GeneProduct ncbigene:12387 full name: catenin (cadherin associated protein), beta 1
Tcf3 GeneProduct ncbigene:21415 full name: transcription factor 3
Itgb1 GeneProduct ncbigene:16412 full name: integrin beta 1 (fibronectin receptor beta)
Gsk3b GeneProduct ncbigene:56637 full name: glycogen synthase kinase 3 beta
Dvl1 GeneProduct ncbigene:13542 full name: dishevelled, dsh homolog 1 (Drosophila)
Hdac4 GeneProduct ncbigene:208727 full name: histone deacetylase 4
Phf17 GeneProduct ncbigene:269424 full name: PHD finger protein 17
Fzd1 GeneProduct ncbigene:14362 full name: frizzled homolog 1 (Drosophila)
Lrp5 GeneProduct ncbigene:16973 full name: low density lipoprotein receptor-related protein 5
Wnt3a GeneProduct ncbigene:22416 full name: wingless-related MMTV integration site 3A
Ptpn11 GeneProduct ncbigene:19247 full name: protein tyrosine phosphatase, non-receptor type 11
Grb2 GeneProduct ncbigene:14784 full name: growthfactorreceptor-boundprotein2
Zfp42 GeneProduct ncbigene:22702 full name: zinc finger protein 42
Ep300 GeneProduct ncbigene:328572 full name: E1A binding protein p300
Utf1 GeneProduct ncbigene:22286 full name: undifferentiated embryonic cell transcription factor 1
Esrrb GeneProduct ncbigene:26380 full name: estrogen related receptor, beta
Phc1 GeneProduct ncbigene:13619 full name: polyhomeotic-like 1 (Drosophila)
Zic2 GeneProduct ncbigene:22772 full name: zinc finger protein of the cerebellum 2
Etv5 GeneProduct ncbigene:104156 full name: ets variant gene 5
Tcfap2c GeneProduct ncbigene:21420 full name: transcription factor AP-2, gamma
Otx2 GeneProduct ncbigene:18424 full name: orthodenticle homolog 2 (Drosophila)
Zfp219 GeneProduct ncbigene:69890 full name: zinc finger protein 219
Rybp GeneProduct ncbigene:56353 full name: RING1 and YY1 binding protein
Tle4 GeneProduct ncbigene:21888 full name: Transducin-likeenhancerofsplit4
Rbpj GeneProduct ncbigene:19664 full name: recombination signal binding protein for immunoglobulin kappa J region
Sall1 GeneProduct ncbigene:58198 full name: sal-like 1 (Drosophila)
Fos GeneProduct ncbigene:14281 full name: FBJ osteosarcoma oncogene
Paf1 GeneProduct ncbigene:54624 full name: Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
Tcfe3 GeneProduct ncbigene:209446 full name: transcription factor E3
Kat5 GeneProduct ncbigene:81601 full name: K(lysine) acetyltransferase 5
Sos1 GeneProduct ncbigene:20662 full name: Son of sevenless homolog 1 (Drosophila)
Inhbb GeneProduct ncbigene:16324 full name: inhibin beta-B
Tgfb1 GeneProduct ncbigene:21803 full name: transforming growth factor, beta 1
Smad7 GeneProduct ncbigene:17131 full name: MADhomolog7
Ewsr1 GeneProduct ncbigene:14030 full name: Ewing sarcoma breakpoint region 1
Smarcc1 GeneProduct ncbigene:20588 full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Parp1 GeneProduct ncbigene:11545 full name: poly (ADP-ribose) polymerase family, member 1
Ctcf GeneProduct ncbigene:13018 full name: CCCTC-binding factor
Tsix GeneProduct ncbigene:22097 full name: X (inactive)-specific transcript, antisense
Mitf GeneProduct ncbigene:17342 full name: microphthalmia-associated transcription factor
Xite GeneProduct ncbigene:619209 full name: X-inactivation intergenic transcription element
Kdm4c GeneProduct ncbigene:76804 full name: lysine (K)-specific demethylase 4C
Kdm3a GeneProduct ncbigene:104263 full name: lysine (K)-specific demethylase 3A
Zfp57 GeneProduct ncbigene:22715 full name: zinc finger protein 57
Kpna2 GeneProduct ncbigene:16647 full name: karyopherin (importin) alpha 2
Casp3 GeneProduct ncbigene:12367 full name: caspase 3
Rtn4r GeneProduct ncbigene:65079 full name: reticulon 4 receptor
Cd44 GeneProduct ncbigene:12505 full name: CD44 antigen
Mapk1 GeneProduct ncbigene:26413 full name: mitogen-activated protein kinase 1
Nme2 GeneProduct ncbigene:18103 full name: non-metastatic cells 2, protein (NM23B) expressed in
Tcfeb GeneProduct ncbigene:21425 full name: transcription factor EB
Ehmt2 GeneProduct ncbigene:110147 full name: euchromatic histone lysine N-methyltransferase 2
Dnmt3l GeneProduct ncbigene:54427 full name: DNA (cytosine-5-)-methyltransferase 3-like
Irs1 GeneProduct ncbigene:16367 full name: insulin receptor substrate 1
Insr GeneProduct ncbigene:16337 full name: insulin receptor
Ins1 GeneProduct ncbigene:16333 full name: insulin I
Shh GeneProduct ncbigene:20423 full name: sonic hedgehog
Smo GeneProduct ncbigene:319757 full name: smoothened homolog (Drosophila)
Ehmt1 GeneProduct ncbigene:77683 full name: euchromatic histone methyltransferase 1
Gadd45gip1 GeneProduct ncbigene:102060 full name: growth arrest and DNA-damage-inducible, gamma interacting protein 1
Ncoa1 GeneProduct ncbigene:17977 full name: nuclear receptor coactivator 1
Ctbp2 GeneProduct ncbigene:13017 full name: C-terminal binding protein 2
Prkaca GeneProduct ncbigene:18747 full name: protein kinase, cAMP dependent, catalytic, alpha
Dnmt3a GeneProduct ncbigene:13435 full name: DNA methyltransferase 3A
Dnmt3b GeneProduct ncbigene:13436 full name: DNA methyltransferase 3B
Tcfap2a GeneProduct ncbigene:21418 full name: transcription factor AP-2, alpha
Satb1 GeneProduct ncbigene:20230 full name: special AT-rich sequence binding protein 1
Satb2 GeneProduct ncbigene:212712 full name: special AT-rich sequence binding protein 2
Pax6 GeneProduct ncbigene:77766 full name: paired box gene 6
Spp1 GeneProduct ncbigene:20750 full name: secreted phosphoprotein 1
Pias4 GeneProduct ncbigene:59004 full name: protein inhibitor of activated STAT 4; PIASy
Wwp2 GeneProduct ncbigene:66894 full name: WW domain containing E3 ubiquitin protein ligase 2
Creb1 GeneProduct ncbigene:12912 full name: cAMP responsive element binding protein 1
Uhrf1 GeneProduct ncbigene:18140 full name: ubiquitin-like, containing PHD and RING finger domains, 1
Rcn2 GeneProduct ncbigene:26611 full name: reticulocalbin 2
Stk40 GeneProduct ncbigene:74178 full name: serine/threonine kinase 40
Fgf5 GeneProduct ncbigene:14176 full name: fibroblast growth factor 5
Dazl GeneProduct ncbigene:13164 full name: deleted in azoospermia-like
Grsf1 GeneProduct ncbigene:231413 full name: G-rich RNA sequence binding factor 1
Aes GeneProduct ncbigene:14797 full name: amino-terminal enhancer of split
Pim1 GeneProduct ncbigene:18712 full name: proviral integration site 1
Pim3 GeneProduct ncbigene:223775 full name: proviral integration site 3
Ocln GeneProduct ncbigene:18260 full name: occludin
Atf2 GeneProduct ncbigene:11909 full name: activating transcription factor 2
Icam1 GeneProduct ncbigene:15894 full name: intercellular adhesion molecule 1
Brca1 GeneProduct ncbigene:12189 full name: breast cancer 1
Sumo1 GeneProduct ncbigene:22218 full name: SMT3 suppressor of mif two 3 homolog 1 (yeast)
Tet1 GeneProduct ncbigene:52463 full name: tet oncogene 1
T GeneProduct ncbigene:20997 full name: brachyury
Gbx2 GeneProduct ncbigene:14472 full name: gastrulation brain homeobox 2
Nr2f6 GeneProduct ncbigene:13864 full name: nuclear receptor subfamily 2, group F, member 6
Nr2c1 GeneProduct ncbigene:22025 full name: nuclear receptor subfamily 2, group C, member 1
Sf1 GeneProduct ncbigene:22668 full name: splicing factor 1
Usp7 GeneProduct ncbigene:252870 full name: ubiquitin specific peptidase 7
Cabin1 GeneProduct ncbigene:104248 full name: calcineurin binding protein 1
Pin1 GeneProduct ncbigene:23988 full name: protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
Rock1 GeneProduct ncbigene:19877 full name: Rho-associated coiled-coil containing protein kinase 1
Rock2 GeneProduct ncbigene:19878 full name: Rho-associated coiled-coil containing protein kinase 2
Prkcc GeneProduct ncbigene:18752 full name: protein kinase C, gamma
E130012A19Rik GeneProduct ncbigene:103551 full name: RIKEN cDNA E130012A19 gene
Igfbp3 GeneProduct ncbigene:16009 full name: insulin-like growth factor binding protein 3
Bcam GeneProduct ncbigene:57278 full name: basal cell adhesion molecule
1600029D21Rik GeneProduct ncbigene:76509 full name: RIKEN cDNA 1600029D21 gene
Perp GeneProduct ncbigene:64058 full name: PERP, TP53 apoptosis effector
Dgka GeneProduct ncbigene:13139 full name: diacylglycerol kinase, alpha
Hira GeneProduct ncbigene:15260 full name: histone cell cycle regulation defective homolog A (S. cerevisiae)
Fam129a GeneProduct ncbigene:63913 full name: family with sequence similarity 129, member A
Hck GeneProduct ncbigene:15162 full name: hemopoietic cell kinase
Acvr1c GeneProduct ncbigene:269275 full name: activin A receptor, type IC / Alk7
Smarca5 GeneProduct ncbigene:93762 full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Ssrp1 GeneProduct ncbigene:20833 full name: structure specific recognition protein 1
Sall3 GeneProduct ncbigene:20689 full name: sal-like 3 (Drosophila)
Chd4 GeneProduct ncbigene:107932 full name: chromodomain helicase DNA binding protein 4
H3f3a GeneProduct ncbigene:15078 full name: H3 histone, family 3A
Atrx GeneProduct ncbigene:22589 full name: alpha thalassemia/mental retardation syndrome X-linked homolog (human)
Nkd1 GeneProduct ncbigene:93960 full name: naked cuticle 1 homolog (Drosophila)
Ppp2r1a GeneProduct ncbigene:51792 full name: protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
Nobox GeneProduct ncbigene:18291 full name: NOBOX oogenesis homeobox
Gdf9 GeneProduct ncbigene:14566 full name: growth differentiation factor 9
Acvr1b GeneProduct ncbigene:11479 full name: activin A receptor, type 1B / Alk4
Mtf2 GeneProduct ncbigene:17765 full name: metal response element binding transcription factor 2 / PCL2
Rbbp4 GeneProduct ncbigene:19646 full name: retinoblastoma binding protein 4
Rbbp7 GeneProduct ncbigene:245688 full name: retinoblastoma binding protein 7
Suz12 GeneProduct ncbigene:52615 full name: suppressor of zeste 12 homolog (Drosophila)
Jarid2 GeneProduct ncbigene:16468 full name: jumonji, AT rich interactive domain 2
Nppb GeneProduct ncbigene:18158 full name: natriuretic peptide precursor type B
Npr1 GeneProduct ncbigene:18160 full name: natriuretic peptide receptor 1
Cad GeneProduct ncbigene:69719 full name: carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Dffa GeneProduct ncbigene:13347 full name: DNA fragmentation factor, alpha subunit
Ezh2 GeneProduct ncbigene:14056 full name: enhancer of zeste homolog 2 (Drosophila)
Smad3 GeneProduct ncbigene:17127 full name: MAD homolog 3 (Drosophila)
Ezh1 GeneProduct ncbigene:14055 full name: enhancer of zeste homolog 1 (Drosophila)
Eed GeneProduct ncbigene:13626 full name: embryonic ectoderm development
Ipo7 GeneProduct ncbigene:233726 full name: importin 7
Kpnb1 GeneProduct ncbigene:16211 full name: karyopherin (importin) beta 1
Xpo4 GeneProduct ncbigene:57258 full name: exportin 4
Ipo9 GeneProduct ncbigene:226432 full name: importin 9
Sp3 GeneProduct ncbigene:20687 full name: trans-acting transcription factor 3
Terf2 GeneProduct ncbigene:21750 full name: telomeric repeat binding factor 2
Hand2 GeneProduct ncbigene:15111 full name: heart and neural crest derivatives expressed transcript 2
Dpysl2 GeneProduct ncbigene:12934 full name: dihydropyrimidinase-like 2
Kdm5c GeneProduct ncbigene:20591 full name: lysine (K)-specific demethylase 5C
Kdm6b GeneProduct ncbigene:216850 full name: KDM1 lysine (K)-specific demethylase 6B
Mll2 GeneProduct ncbigene:381022 full name: myeloid/lymphoid or mixed-lineage leukemia 2, ALR
Kdm6a GeneProduct ncbigene:22289 full name: 4lysine (K)-specific demethylase 6A
Mef2c GeneProduct ncbigene:17260 full name: myocyte enhancer factor 2C
Mef2d GeneProduct ncbigene:17261 full name: myocyte enhancer factor 2D
Myod1 GeneProduct ncbigene:17927 full name: myogenic differentiation 1
Smurf1 GeneProduct ncbigene:75788 full name: SMAD specific E3 ubiquitin protein ligase 1
Sgk1 GeneProduct ncbigene:20393 full name: serum/glucocorticoid regulated kinase 1
Nedd4l GeneProduct ncbigene:83814 full name: neural precursor cell expressed, developmentally down-regulated gene 4-like
Hif1a GeneProduct ncbigene:15251 full name: hypoxia inducible factor 1, alpha subunit
Dppa4 GeneProduct ncbigene:73693 full name: developmental pluripotency associated 4
Klf2 GeneProduct ncbigene:16598 full name: Kruppel-like factor 2 (lung)
Hells GeneProduct ncbigene:15201 full name: helicase, lymphoid specific
Dnmt1 GeneProduct ncbigene:13433 full name: DNA methyltransferase (cytosine-5) 1
Ctr9 GeneProduct ncbigene:22083 full name: Ctr9 (Alco called 'SH2 domain-binding protein 1')
Leo1 GeneProduct ncbigene:235497 full name: Leo1
Cdc73 GeneProduct ncbigene:214498 full name: cell division cycle 73, Paf1/RNA polymerase II complex component, homolog
Wdr61 GeneProduct ncbigene:66317 full name: WD repeat domain 61
Carm1 GeneProduct ncbigene:74766 full name: coactivator-associated arginine methyltransferase 1
Rbl2 GeneProduct ncbigene:19651 full name: retinoblastoma-like 2
Cdk2 GeneProduct ncbigene:12566 full name: cyclin-dependent kinase 2
Relb GeneProduct ncbigene:19698 full name: avian reticuloendotheliosis viral (v-rel) oncogene related B
Setdb1 GeneProduct ncbigene:76893 full name: SET domain, bifurcated 1
Ncl GeneProduct ncbigene:17975 full name: nucleolin
Lyar GeneProduct ncbigene:17089 full name: Ly1 antibody reactive clone
Trim24 GeneProduct ncbigene:21848 full name: tripartite motif-containing 24
Twist1 GeneProduct ncbigene:22160 full name: twist gene homolog 1 (Drosophila)
Zscan10 GeneProduct ncbigene:332221 full name: zinc finger and SCAN domain containing 10
Smarca2 GeneProduct ncbigene:67155 full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
Pml GeneProduct ncbigene:18854 full name: promyelocytic leukemia
Kdm1a GeneProduct ncbigene:99982 full name: lysine (K)-specific demethylase 1A
Gatad2a GeneProduct ncbigene:234366 full name: GATA zinc finger domain containing 2A
Rela GeneProduct ncbigene:19697 full name: v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Smarca4 GeneProduct ncbigene:20586 full name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Gatad2b GeneProduct ncbigene:229542 full name: GATA zinc finger domain containing 2B
Pbrm1 GeneProduct ncbigene:66923 full name: polybromo 1 / BAF180
Hdac1 GeneProduct ncbigene:433759 full name: histone deacetylase 1
Mta1 GeneProduct ncbigene:116870 full name: metastasis associated 1
Sin3a GeneProduct ncbigene:20466 full name: transcriptional regulator, SIN3A (yeast)
Klf5 GeneProduct ncbigene:12224 full name: Kruppel-like factor 5
Mta2 GeneProduct ncbigene:23942 full name: metastasis-associated gene family, member 2
Zmym2 GeneProduct ncbigene:76007 full name: zinc finger, MYM-type 2
Tle2 GeneProduct ncbigene:21886 full name: transducin-like enhancer of split 2, homolog of Drosophila E(spl)


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  3. Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. Smith ML, Chen IT, Zhan Q, Bae I, Chen CY, Gilmer TM, et al. Science. 1994 Nov 25;266(5189):1376–80. PubMed Europe PMC Scholia
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