Adipogenesis (WP155)

Rattus norvegicus

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.


Mary-Elizabeth Patti , Martijn Van Iersel , and Martina Summer-Kutmon


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Rattus norvegicus



Pathway Ontology

signaling pathway pertinent to development


Label Type Compact URI Comment
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Bscl2 GeneProduct ncbigene:361722
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Zmpste24 GeneProduct ncbigene:313564
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Lpin2 GeneProduct ncbigene:316737
Lipe GeneProduct ncbigene:25330
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Pck2 GeneProduct ncbigene:361042
Cebpa GeneProduct ncbigene:24252
Irs2 GeneProduct ncbigene:29376
Lpin3 GeneProduct ncbigene:362261
E2F4 GeneProduct ncbigene:307794


  1. Molecular regulation of adipogenesis. Rosen ED, Spiegelman BM. Annu Rev Cell Dev Biol. 2000;16:145–71. PubMed Europe PMC Scholia