Valine, leucine and isoleucine degradation (WP1451)
Caenorhabditis elegans
Authors
Pieter Giesbertz , Kristina Hanspers , Andra Waagmeester , Egon Willighagen , Alex Pico , and Marianthi KalafatiActivity
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Organisms
Caenorhabditis elegansCommunities
Annotations
Pathway Ontology
classic metabolic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| (S)-3-Hydroxyisobutyric acid | Metabolite | hmdb:HMDB0000023 | |
| Ketoleucine | Metabolite | hmdb:HMDB0000695 | |
| S-Methylmalonyl-CoA | Metabolite | hmdb:HMDB0002310 | |
| S-3-Methyl-2-oxopentanoic acid | Metabolite | pubchem.compound:47 | |
| S-Methylmalonic acid semialdehyde | Metabolite | hmdb:HMDB0002217 | |
| Tiglyl-CoA | Metabolite | hmdb:HMDB0002054 | |
| Acetoacetyl-CoA | Metabolite | hmdb:HMDB0001484 | |
| Isovaleryl-CoA | Metabolite | hmdb:HMDB0001113 | |
| a-Ketoisovaleric acid | Metabolite | hmdb:HMDB0000019 | |
| Acetoacetic acid | Metabolite | chebi:15344 | |
| Propionyl-CoA | Metabolite | hmdb:HMDB0001275 | |
| 3-Methyl-1-hydroxybutyl-ThPP | Metabolite | hmdb:HMDB0006865 | |
| 2-Methyl-3-hydroxybutyryl-CoA | Metabolite | hmdb:HMDB0001356 | |
| Methylmalonic acid | Metabolite | hmdb:HMDB0000202 | |
| S-(2-Methylpropionyl)-dihydrolipoamide-E | Metabolite | hmdb:HMDB0006868 | |
| L-Valine | Metabolite | hmdb:HMDB0000883 | |
| L-Isoleucine | Metabolite | hmdb:HMDB0000172 | |
| L-Leucine | Metabolite | hmdb:HMDB0000687 | |
| (S)-3-Hydroxyisobutyryl-CoA | Metabolite | hmdb:HMDB0001052 | |
| 3-Methylglutaconyl-CoA | Metabolite | pubchem.compound:25244136 | |
| 2-Methylacetoacetyl-CoA | Metabolite | hmdb:HMDB0001157 | |
| R-Methylmalonyl-CoA | Metabolite | hmdb:HMDB0002255 | |
| S-(3-Methylbutanoyl)-dihydrolipoamide-E | Metabolite | hmdb:HMDB0006867 | |
| Acetyl-CoA | Metabolite | hmdb:HMDB0001206 | |
| Methacrylyl-CoA | Metabolite | hmdb:HMDB0001011 | |
| Branched-chain fatty acid | Metabolite | chebi:35819 | |
| Succinyl-CoA | Metabolite | hmdb:HMDB0001022 | |
| 3-Hydroxyisovaleryl-CoA | Metabolite | hmdb:HMDB0006870 | |
| Isobutyryl-CoA | Metabolite | hmdb:HMDB0001243 | |
| 2-Methyl-1-hydroxypropyl-ThPP | Metabolite | hmdb:HMDB0006866 | |
| S-(2-Methylbutanoyl)-dihydrolipoamide-E | Metabolite | hmdb:HMDB0006869 | |
| 3-Methylcrotonyl-CoA | Metabolite | hmdb:HMDB0001493 | |
| S-2-Methylbutanoyl-CoA | Metabolite | pubchem.compound:23724628 | |
| 2-Methyl-1-hydroxybutyl-ThPP | Metabolite | hmdb:HMDB0012310 | |
| 3-Hydroxy-3-methylglutaryl-CoA | Metabolite | hmdb:HMDB0001375 | |
| acdh-3 | GeneProduct | wormbase:K06A5.6 | Original kegg element: gene;41;cel:K06A5.6 |
| acdh-3 | GeneProduct | wormbase:K06A5.6 | Original kegg element: gene;41;cel:K06A5.6 |
| F32B6.2 | GeneProduct | ensembl:F32B6.2 | |
| acdh-8 | GeneProduct | wormbase:K05F1.3 | |
| ech-2 | GeneProduct | wormbase:F38H4.8 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| ech-3 | GeneProduct | wormbase:F43H9.1 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| ech-5 | GeneProduct | wormbase:F56B3.5 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| ech-6 | GeneProduct | wormbase:T05G5.6 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| ech-7 | GeneProduct | wormbase:Y105E8A.4 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| acdh-10 | GeneProduct | wormbase:T08G2.3 | Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5 |
| acdh-7 | GeneProduct | wormbase:T25G12.5 | Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5 |
| ech-6 | GeneProduct | wormbase:T05G5.6 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| ech-3 | GeneProduct | wormbase:F43H9.1 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| ech-2 | GeneProduct | wormbase:F38H4.8 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| ech-7 | GeneProduct | wormbase:Y105E8A.4 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| ech-5 | GeneProduct | wormbase:F56B3.5 | Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4 |
| acdh-10 | GeneProduct | wormbase:T08G2.3 | Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5 |
| acdh-7 | GeneProduct | wormbase:T25G12.5 | Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5 |
| acdh-10 | GeneProduct | wormbase:T08G2.3 | Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5 |
| acdh-7 | GeneProduct | wormbase:T25G12.5 | Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5 |
| ivd-1 | GeneProduct | wormbase:C02B10.1 | Original kegg element: gene;41;cel:K06A5.6 |
| T02G5.7 | GeneProduct | ensembl:WBGene00020166 | |
| K09H11.1 | GeneProduct | ncbigene:178962 | |
| ech-1 | GeneProduct | wormbase:C29F3.1 | |
| T08B2.7 | GeneProduct | ensembl:WBGene00020347 | |
| T08B2.7 | GeneProduct | ensembl:WBGene00020347 | |
| K09H11.1 | GeneProduct | ncbigene:178962 | |
| Y44A6D.5 | GeneProduct | ncbigene:180361 | |
| B0303.3 | GeneProduct | ensembl:WBGene00015125 | |
| bcat-1 | GeneProduct | wormbase:K02A4.1 | Original kegg element: gene;37;cel:K02A4.1 cel:Y44A6D.5 |
| ard-1 | GeneProduct | wormbase:F01G4.2 | |
| F53A2.7 | GeneProduct | ensembl:WBGene00009952 | |
| T02G5.4 | GeneProduct | ensembl:WBGene00020164 | |
| Y39E4A.3 | GeneProduct | wormbase:Y39E4A.3 | Original kegg element: gene;12;cel:F27D4.5 cel:Y39E4A.3 |
| K09H11.1 | GeneProduct | ncbigene:178962 | |
| acdh-8 | GeneProduct | wormbase:K05F1.3 | |
| pccb-1 | GeneProduct | wormbase:F52E4.1 | |
| ech-9 | GeneProduct | wormbase:F01G10.3 | |
| tag-173 | GeneProduct | wormbase:F27D4.5 | Original kegg element: gene;43;cel:F27D4.5 cel:Y39E4A.3 |
| ZK669.4 | GeneProduct | ncbigene:174279 | |
| Y39E4A.3 | GeneProduct | wormbase:Y39E4A.3 | Original kegg element: gene;12;cel:F27D4.5 cel:Y39E4A.3 |
| acdh-8 | GeneProduct | wormbase:K05F1.3 | |
| B0272.3 | GeneProduct | ensembl:WBGene00007129 | |
| C05C10.3 | GeneProduct | ensembl:WBGene00007330 | |
| ech-1 | GeneProduct | wormbase:C29F3.1 | |
| tag-173 | GeneProduct | wormbase:F27D4.5 | Original kegg element: gene;43;cel:F27D4.5 cel:Y39E4A.3 |
| F54C8.1 | GeneProduct | ncbigene:186222 | |
| hacd-1 | GeneProduct | wormbase:R09B5.6 | |
| Y71G12B.10 | GeneProduct | ensembl:WBGene00022150 | |
| ech-8 | GeneProduct | wormbase:F01G10.2 | |
| kat-1 | GeneProduct | wormbase:T02G5.8 | |
| pcca-1 | GeneProduct | wormbase:F27D9.5 |