Neurotransmitter release in cholinergic motor neurons (WP1401)

Caenorhabditis elegans

G-protein signaling pathways regulating neurotransmitter release in cholinergic motor neurons. Adapted from Fox et al. BMC Genomics 2005 6:42 [ doi:10.1186/1471-2164-6-42].


Thomas Kelder , Daniela Digles , Egon Willighagen , Martina Summer-Kutmon , and Alex Pico


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Caenorhabditis elegans



Pathway Ontology

neuron-to-neuron signaling pathway via the chemical synapse


Label Type Compact URI Comment
GABA Metabolite chebi:16865
Acetylcholine Metabolite chebi:15355
Serotonin Metabolite chebi:28790
Dopamine Metabolite chebi:18243
gbb-1 GeneProduct ensembl:WBGene00021528
gar-3 GeneProduct hgnc.symbol:Y40H4A.1
dop-1 GeneProduct ensembl:WBGene00001052
gar-2 GeneProduct wormbase:WBGene00001519
dop-3 GeneProduct wormbase:WBGene00020506
ser-4 GeneProduct ensembl:WBGene00004779
goa-1 GeneProduct ensembl:WBGene00001648
egl-30 GeneProduct ensembl:WBGene00001196
egl-10 GeneProduct wormbase:WBGene00001179
gpb-2 GeneProduct wormbase:WBGene00001680
egl-8 GeneProduct ensembl:WBGene00001177
ric-8 GeneProduct wormbase:WBGene00004367
egl-16 GeneProduct ncbiprotein:F52E10.1
unc-13 GeneProduct ensembl:WBGene00006752
pkc-1 GeneProduct ensembl:WBGene00004032
dgk-1 GeneProduct ensembl:WBGene00000958
ric-8 GeneProduct wormbase:WBGene00004367
gsa-1 GeneProduct ensembl:WBGene00001745
acy-1 GeneProduct ensembl:WBGene00000068
kin-2 GeneProduct ensembl:WBGene00002190


  1. A gene expression fingerprint of C. elegans embryonic motor neurons. Fox RM, Von Stetina SE, Barlow SJ, Shaffer C, Olszewski KL, Moore JH, et al. BMC Genomics. 2005 Mar 21;6:42. PubMed Europe PMC Scholia