Transcriptional activation by Nfe2l2 in response to phytochemicals (WP1245)

Mus musculus

Based on [ Surh, 2003, figure 4].


Daniela Digles , Susan Coort , Martina Summer-Kutmon , and Eric Weitz


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Mus musculus



Pathway Ontology

nuclear factor, erythroid 2 like 2 signaling pathway


Label Type Compact Identifier Comment
Sulforaphane Metabolite hmdb:HMDB0005792
Curcumin Metabolite hmdb:HMDB0002269
Prkca GeneProduct ncbigene:18750
Mapk8 GeneProduct ncbigene:26419
Aimp2 GeneProduct ncbigene:231872
Cebpb GeneProduct ncbigene:12608
Nfe2l2 GeneProduct ncbigene:18024
Keap1 GeneProduct ncbigene:50868
Cebpb GeneProduct ncbigene:12608
Gclc GeneProduct ncbigene:14629
Nfe2l2 GeneProduct ncbigene:18024
Hmox1 GeneProduct ncbigene:15368
Maf GeneProduct ncbigene:17132
Ephb2 GeneProduct ncbigene:13844
Pik3ca GeneProduct ncbigene:18706
Gsta2 GeneProduct ncbigene:14858
Nqo1 GeneProduct ncbigene:18104
Gclm GeneProduct ncbigene:14630
Nfe2l2 GeneProduct ncbigene:18024
Keap1 GeneProduct ncbigene:50868


  1. Cancer chemoprevention with dietary phytochemicals. Surh YJ. Nat Rev Cancer. 2003 Oct;3(10):768–80. PubMed Europe PMC Scholia