ID signaling pathway (WP1168)

Canis familiaris

Inhibitor of DNA binding (ID) proteins are members of the helix-loop-helix (HLH) family of proteins which lack a DNA binding domain themselves but bind to other family members inhibiting their DNA binding capacity. This family of proteins is comprised of IDs 1, 2, 3 and 4. They can be stimulated by ligands such as the Vascular Endothelial Growth Factor (VEGF), TGF beta and the T cell receptor. Source: NetPath


Alex Pico , Christine Chichester , and Eric Weitz


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Canis familiaris



Pathway Ontology

Inhibitor of DNA binding signaling pathway


Label Type Compact URI Comment
ID1 GeneProduct ncbigene:609779
ID3 GeneProduct ncbigene:403547
RB1 GeneProduct ncbigene:476915
RBL2 GeneProduct ncbigene:478127
RBL1 GeneProduct ncbigene:477221
TCF3 GeneProduct ncbigene:485079
MYOD1 GeneProduct ncbigene:611940
CDK2 GeneProduct ncbigene:606931
CCNA2 GeneProduct ncbigene:483845
CCNE1 GeneProduct ncbigene:484610
ELK1 GeneProduct ncbigene:491860
ELK4 GeneProduct ncbigene:488574
ELK3 GeneProduct ncbigene:482613
PSMD4 GeneProduct ncbigene:100192385
PAX5 GeneProduct ncbigene:612021
PAX2 GeneProduct ncbigene:609228
PAX8 GeneProduct ncbigene:403927
MYF5 GeneProduct ncbigene:482582
MYF6 GeneProduct ncbigene:611531
MYOG GeneProduct ncbigene:490224
SREBF1 GeneProduct ncbigene:403475
MSC GeneProduct ncbigene:486992
BMP2 GeneProduct ncbigene:477162
VEGFA GeneProduct ncbigene:403802
FLT1 GeneProduct ncbigene:403727
KDR GeneProduct ncbigene:482154
SMAD1 GeneProduct ncbigene:475456
SMAD4 GeneProduct ncbigene:476196
SMAD5 GeneProduct ncbigene:481520
ATF3 GeneProduct ncbigene:612911
SMAD3 GeneProduct ncbigene:610902
TGFB1 GeneProduct ncbigene:403998
ACVRL1 GeneProduct ncbigene:477603
SMAD4 GeneProduct ncbigene:476196
SMAD5 GeneProduct ncbigene:481520
SMAD1 GeneProduct ncbigene:475456
LCK GeneProduct ncbigene:478151
IGF1R GeneProduct ncbigene:442951
IGF1 GeneProduct ncbigene:610255
IRS1 GeneProduct ncbigene:486148
CTNNB1 GeneProduct ncbigene:477032
TERT GeneProduct ncbigene:403412
NFKB1 GeneProduct ncbigene:442859
RELA GeneProduct ncbigene:483729
CD40LG GeneProduct ncbigene:403468
NGF GeneProduct ncbigene:403402
ATF3 GeneProduct ncbigene:612911
SMAD3 GeneProduct ncbigene:610902
EGF GeneProduct ncbigene:403657
TCF7L2 GeneProduct ncbigene:486894