Statin pathway (WP1157)

Canis familiaris

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What are statins? See Wikipedia at: http://en.wikipedia.org/wiki/Statin More about this pathway and statins: https://www.pharmgkb.org/do/serve?objId=PA2031&objCls=Pathway

Authors

Thomas Kelder , Alex Pico , Daniela Digles , Egon Willighagen , and Eric Weitz

Activity

last edited

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Cited In

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Organisms

Canis familiaris

Communities

Annotations

Pathway Ontology

statin drug pathway

Participants

Label Type Compact URI Comment
Phospholipid Metabolite kegg.compound:C00865
VLDL Metabolite chebi:39027
Cholesterol ester Metabolite kegg.compound:C02530
Acetyl-CoA Metabolite hmdb:HMDB0001206
IDL Metabolite kegg.compound:C01834
HDL Metabolite chebi:39025
Fatty acid Metabolite kegg.compound:C00162
LDL Metabolite chebi:39026
Triglyceride Metabolite kegg.compound:C00422
ABCA1 GeneProduct ncbigene:481651
APOA1 GeneProduct ncbigene:479427
APOA4 GeneProduct ncbigene:489392
APOC2 GeneProduct ncbigene:442969
APOC3 GeneProduct ncbigene:442970
APOC1 GeneProduct ncbigene:476437
LOC486962 GeneProduct ncbigene:486962
SCARB1 GeneProduct ncbigene:486241
PLTP GeneProduct ncbigene:485903
LCAT GeneProduct ncbigene:479680
DGAT1 GeneProduct ncbigene:482093
LPL GeneProduct ncbigene:403626
LIPC GeneProduct ncbigene:478320
SOAT1 GeneProduct ncbigene:490325
APOE GeneProduct ncbigene:476438
LRP1 GeneProduct ncbigene:481124
HMGCR GeneProduct ncbigene:479182

References

  1. Direct effects of statins on cells primarily involved in atherosclerosis. Chen H, Ikeda U, Shimpo M, Shimada K. Hypertens Res. 2000 Mar;23(2):187–92. PubMed Europe PMC Scholia