Hepatocyte growth factor receptor signaling (WP1046)
Bos taurus
Signaling pathway of the Hepatocyte Growth Factor Receptor (Homo sapiens) also know as C-Met. The C-Met activation results in the stimulation of a variety of intracellular signalling pathways, which regulate several processes such as: motility, migration, proliferation and invasion.
Authors
Martina Summer-Kutmon , Eric Weitz , and Denise SlenterActivity
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Organisms
Bos taurusCommunities
Annotations
Cell Type Ontology
hepatocytePathway Ontology
Rho/Rac/Cdc42 mediated signaling pathway scatter factor/hepatocyte growth factor signaling pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| FOS | GeneProduct | ensembl:ENSBTAG00000004322 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2353 |
| PTPN11 | GeneProduct | ensembl:ENSBTAG00000002048 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5781 |
| ELK1 | GeneProduct | ensembl:ENSBTAG00000015817 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2002 |
| MAP4K1 | GeneProduct | ensembl:ENSBTAG00000021145 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:11184 |
| PXN | GeneProduct | ensembl:ENSBTAG00000018108 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5829 |
| MAPK1 | GeneProduct | ensembl:ENSBTAG00000010312 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5594 |
| PIK3CA | GeneProduct | ensembl:ENSBTAG00000009232 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5290 |
| PAK1 | GeneProduct | ensembl:ENSBTAG00000010191 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5058 |
| GRB2 | GeneProduct | ensembl:ENSBTAG00000004736 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2885 |
| PXN | GeneProduct | ensembl:ENSBTAG00000018108 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5829 |
| MAPK8 | GeneProduct | ensembl:ENSBTAG00000007876 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5599 |
| C-MET | GeneProduct | ensembl:ENSBTAG00000006161 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4233 |
| PTK2B | GeneProduct | ensembl:ENSBTAG00000005958 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2185 |
| JUN | GeneProduct | ensembl:ENSBTAG00000004037 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3725 |
| SRC | GeneProduct | ensembl:ENSBTAG00000008938 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6714 |
| RAP1B | GeneProduct | ensembl:ENSBTAG00000008967 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5908 |
| CRKL | GeneProduct | ensembl:ENSBTAG00000045548 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1399 |
| GAB1 | GeneProduct | ensembl:ENSBTAG00000002813 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2549 |
| SRC | GeneProduct | ensembl:ENSBTAG00000008938 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6714 |
| HRAS | GeneProduct | ensembl:ENSBTAG00000046644 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3265 |
| STAT3 | GeneProduct | ensembl:ENSBTAG00000021523 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6774 |
| CRK | GeneProduct | ensembl:ENSBTAG00000005665 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1398 |
| PTEN | GeneProduct | ensembl:ENSBTAG00000009498 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5728 |
| MAP2K2 | GeneProduct | ensembl:ENSBTAG00000024450 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5605 |
| RAF1 | GeneProduct | ensembl:ENSBTAG00000045748 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5894 |
| PTK2 | GeneProduct | ensembl:ENSBTAG00000009578 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5747 |
| RAPGEF1 | GeneProduct | ensembl:ENSBTAG00000020791 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2889 |
| RASA1 | GeneProduct | ensembl:ENSBTAG00000009565 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5921 |
| MAPK3 | GeneProduct | ensembl:ENSBTAG00000016156 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5595 |
| RAP1A | GeneProduct | ensembl:ENSBTAG00000014710 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5906 |
| MAP2K1 | GeneProduct | ensembl:ENSBTAG00000033983 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5604 |
| ITGB1 | GeneProduct | ensembl:ENSBTAG00000015910 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3688 |
| PTK2 | GeneProduct | ensembl:ENSBTAG00000009578 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5747 |
| DOCK1 | GeneProduct | ensembl:ENSBTAG00000031890 | Interim Symbol: Dock1 predicted and Name: dedicator of cyto-kinesis 1 (predicted)HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1793 |
| HGF | GeneProduct | ensembl:ENSBTAG00000017664 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3082 |
| PTK2B | GeneProduct | ensembl:ENSBTAG00000005958 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2185 |
| ITGA1 | GeneProduct | ensembl:ENSBTAG00000016525 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3672 |
| SOS1 | GeneProduct | ensembl:ENSBTAG00000011643 | Son of sevenless homolog 1 (Drosophila) (predicted)HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6654 |
References
- An overview of the c-MET signaling pathway. Organ SL, Tsao MS. Ther Adv Med Oncol. 2011 Nov;3(1 Suppl):S7–19. PubMed Europe PMC Scholia