Regulation of Actin Cytoskeleton (Mus musculus)
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Focal complex
assembly
-p
Actin polymerization
stress fiber
RAS
PI3K
Chemotatic factor
Stabilization of actin
Actin polymerization
MAPK Signaling pathway
GPCR
+p
Focal adhesion
pathway
PI3K
Growth Factor (GF)
Adherens junction
pathway
Gene Expression
GPCR
GF
Lamellipodia
RTK
RTK
RAS
Focal adhesion pathway
Filipodia
Focal adhesion
assembly
Actin polymerization
Actomyosin
assembly contraction
Chemotactic factor
stress fiber
?
Pak7
Fgf21
Actb
Pdgfb
Pak6
Tmsb4x
Iqgap1
Fgfr3
Chrm5
Apc
Fgf20
Mapk1
Arhgef4
Mapk4
Rock1
Ssh2
Actb
Pik3cd
Vil1
Ssh3
Pik3c2g
Fgf7
Vav1
Pik3c3
Msn
Fgf5
F2
Cd14
Rhoa
Mylk
Nckap1
Map2k1
Diap3
Pik3r2
Dock1
Fgf22
Ptk2
Pik3r1
Mras
Ins2
Fgf3
Abi2
Pik3ca
Pak3
Braf
Pip4k2c
Actg1
Diap1
Fgf18
Pfn1
Fgf12
Map2k2
Fgf8
Rock2
Fgf1
Cfl1
Egf
Rac3
Pak1
Grlf1
Arpc5
Pip4k2b
Pik3c2a
Ezr
Pip5k1b
Gsn
Cdc42
Arpc5
Fgf13
Mapk3
Pak2
Kras
Pik3r3
Chrm2
Pip5k1a
Bradykinin
Itga1
Pdgfrb
LPS
Rassf7
Pik3r4
Fgf16
Myl3
Fgf14
Fgf10
PIP3
Limk1
Csk
Mos
Raf1
Rac2
Actb
Brk1
Pik3cb
Bcar1
Wasf2
Chrm3
Arhgef6
Gna12
Sos2
Fgfr1
Actn1
Egfr
PIP2
Wasf1
Arhgef7
Fgf2
F2r
Bdkrb1
Pip4k2a
Myh10
Gng12
Vcl
Myl1
Fgfr2
Fgd1
Sos1
Baiap2
Gna13
Fgf11
Pip5k1c
Fgf23
Cfl2
Pip4k2a
Ins1
Actg1
PIP2
Pxn
Rras2
Actg1
Vcl
Fgf9
Arhgef1
Pik3c2b
Pak4
Rras
Pip5kl1
Pik3cg
Rac1
Enah
Fgf4
Nras
Pfn1
Chrm1
Was
Pik3r5
Ppp1r12a
Rac4
Acetylcholine
Fgf15
Baiap2
Fgf17
Fgf6
Fn1
Git1
Rac1p2
Ssh1
Cyfip2
Arhgef6
Pdgfra
Mapk6
Crk
Chrm4
Slc9a1
Fgfr4
Apc2
Pdgfa
Rdx
Bdkrb2
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP51(r20783)
with a 94% conversion rate.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
109403
view
17:32, 16 March 2020
L Dupuis
Converted interactions to graphical lines
106901
view
13:37, 17 September 2019
MaintBot
HMDB identifier normalization
104995
view
04:25, 28 June 2019
Khanspers
removed KEGG comments
71326
view
17:17, 17 October 2013
MaintBot
Automated update of data sources
69146
view
18:17, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67624
view
11:34, 26 June 2013
Ddigles
Ontology Term : 'cell adhesion signaling pathway' added !
47746
view
19:30, 5 April 2012
Thomas
fixed wrongly annotated genes
41334
view
00:25, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34401
view
23:01, 9 December 2009
MaintBot
Automatic update of empty xrefs
33048
view
22:09, 7 October 2009
MaintBot
Added xrefs
32455
view
17:23, 15 August 2009
MaintBot
Fixed text labels
32137
view
13:57, 14 August 2009
MaintBot
Fixed group labels
31168
view
23:59, 7 August 2009
Nsalomonis
cleaned up conversion
30894
view
00:22, 30 July 2009
MaintBot
Converted from Homo sapiens
21778
view
11:32, 14 November 2008
MaintBot
[[Pathway:Mus musculus:Regulation of Actin Cytoskeleton KEGG]] moved to [[Pathway:WP523]]: Moved to stable identifier
8356
view
13:46, 7 January 2008
MaintBot
[[Pathway:Mouse:Regulation of Actin Cytoskeleton KEGG]] moved to [[Pathway:Mus musculus:Regulation of Actin Cytoskeleton KEGG]]: Renaming species
7796
view
16:18, 18 December 2007
MaintBot
fixed category names
7290
view
12:41, 4 November 2007
MaintBot
Added categories to GPML
6490
view
22:19, 22 May 2007
169.230.77.174
gpml file for [[Mouse:Regulation_of_Actin_Cytoskeleton_KEGG]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Abi2
GeneProduct
329165 (Entrez Gene)
Acetylcholine
Metabolite
HMDB0000895 (HMDB)
Actb
GeneProduct
11461 (Entrez Gene)
Actg1
GeneProduct
11465 (Entrez Gene)
Actn1
GeneProduct
109711 (Entrez Gene)
Apc
GeneProduct
11789 (Entrez Gene)
Apc2
GeneProduct
23805 (Entrez Gene)
Arhgef1
GeneProduct
16801 (Entrez Gene)
Arhgef4
GeneProduct
226970 (Entrez Gene)
Arhgef6
GeneProduct
73341 (Entrez Gene)
Arhgef7
GeneProduct
54126 (Entrez Gene)
Arpc5
GeneProduct
67771 (Entrez Gene)
Baiap2
GeneProduct
108100 (Entrez Gene)
Bcar1
GeneProduct
12927 (Entrez Gene)
Bdkrb1
GeneProduct
12061 (Entrez Gene)
Bdkrb2
GeneProduct
12062 (Entrez Gene)
Bradykinin
Metabolite
HMDB0004246 (HMDB)
Braf
GeneProduct
109880 (Entrez Gene)
Brk1
Protein
Q91VR8 (Uniprot-TrEMBL)
Cd14
GeneProduct
12475 (Entrez Gene)
Cdc42
GeneProduct
12540 (Entrez Gene)
Cfl1
GeneProduct
12631 (Entrez Gene)
Cfl2
GeneProduct
12632 (Entrez Gene)
Chrm1
GeneProduct
12669 (Entrez Gene)
Chrm2
GeneProduct
243764 (Entrez Gene)
Chrm3
GeneProduct
12671 (Entrez Gene)
Chrm4
GeneProduct
12672 (Entrez Gene)
Chrm5
GeneProduct
213788 (Entrez Gene)
Crk
GeneProduct
12928 (Entrez Gene)
Csk
GeneProduct
12988 (Entrez Gene)
Cyfip2
GeneProduct
76884 (Entrez Gene)
Diap1
GeneProduct
13367 (Entrez Gene)
Diap3
GeneProduct
56419 (Entrez Gene)
Dock1
GeneProduct
330662 (Entrez Gene)
Egf
GeneProduct
13645 (Entrez Gene)
Egfr
GeneProduct
13649 (Entrez Gene)
Enah
GeneProduct
13800 (Entrez Gene)
Ezr
GeneProduct
22350 (Entrez Gene)
F2
GeneProduct
14061 (Entrez Gene)
F2r
GeneProduct
14062 (Entrez Gene)
Fgd1
GeneProduct
14163 (Entrez Gene)
Fgf10
GeneProduct
14165 (Entrez Gene)
Fgf11
GeneProduct
14166 (Entrez Gene)
Fgf1
GeneProduct
14164 (Entrez Gene)
Fgf12
GeneProduct
14167 (Entrez Gene)
Fgf13
GeneProduct
14168 (Entrez Gene)
Fgf14
GeneProduct
14169 (Entrez Gene)
Fgf15
GeneProduct
14170 (Entrez Gene)
Fgf16
GeneProduct
80903 (Entrez Gene)
Fgf17
GeneProduct
14171 (Entrez Gene)
Fgf18
GeneProduct
14172 (Entrez Gene)
Fgf20
GeneProduct
80857 (Entrez Gene)
Fgf2
GeneProduct
14173 (Entrez Gene)
Fgf21
GeneProduct
56636 (Entrez Gene)
Fgf22
GeneProduct
67112 (Entrez Gene)
Fgf23
GeneProduct
64654 (Entrez Gene)
Fgf3
GeneProduct
14174 (Entrez Gene)
Fgf4
GeneProduct
14175 (Entrez Gene)
Fgf5
GeneProduct
14176 (Entrez Gene)
Fgf6
GeneProduct
14177 (Entrez Gene)
Fgf7
GeneProduct
14178 (Entrez Gene)
Fgf8
GeneProduct
14179 (Entrez Gene)
Fgf9
GeneProduct
14180 (Entrez Gene)
Fgfr1
GeneProduct
14182 (Entrez Gene)
Fgfr2
GeneProduct
14183 (Entrez Gene)
Fgfr3
GeneProduct
14184 (Entrez Gene)
Fgfr4
GeneProduct
14186 (Entrez Gene)
Fn1
GeneProduct
14268 (Entrez Gene)
Git1
GeneProduct
216963 (Entrez Gene)
Gna12
GeneProduct
14673 (Entrez Gene)
Gna13
GeneProduct
14674 (Entrez Gene)
Gng12
GeneProduct
14701 (Entrez Gene)
Grlf1
GeneProduct
232906 (Entrez Gene)
Gsn
GeneProduct
227753 (Entrez Gene)
Ins1
GeneProduct
16333 (Entrez Gene)
Ins2
GeneProduct
16334 (Entrez Gene)
Iqgap1
GeneProduct
29875 (Entrez Gene)
Itga1
GeneProduct
109700 (Entrez Gene)
Kras
GeneProduct
16653 (Entrez Gene)
LPS
Metabolite
C00338 (KEGG Compound)
Limk1
GeneProduct
16885 (Entrez Gene)
Map2k1
GeneProduct
26395 (Entrez Gene)
Map2k2
GeneProduct
26396 (Entrez Gene)
Mapk1
GeneProduct
26413 (Entrez Gene)
Mapk3
GeneProduct
26417 (Entrez Gene)
Mapk4
GeneProduct
225724 (Entrez Gene)
Mapk6
GeneProduct
50772 (Entrez Gene)
Mos
GeneProduct
17451 (Entrez Gene)
Mras
GeneProduct
17532 (Entrez Gene)
Msn
GeneProduct
17698 (Entrez Gene)
Myh10
GeneProduct
77579 (Entrez Gene)
Myl1
GeneProduct
17901 (Entrez Gene)
Myl3
GeneProduct
17897 (Entrez Gene)
Mylk
GeneProduct
107589 (Entrez Gene)
Nckap1
GeneProduct
50884 (Entrez Gene)
Nras
GeneProduct
18176 (Entrez Gene)
PIP2
Metabolite
C04637 (KEGG Compound)
PIP3
Metabolite
C05981 (KEGG Compound)
Pak1
GeneProduct
18479 (Entrez Gene)
Pak2
GeneProduct
224105 (Entrez Gene)
Pak3
GeneProduct
18481 (Entrez Gene)
Pak4
GeneProduct
70584 (Entrez Gene)
Pak6
GeneProduct
214230 (Entrez Gene)
Pak7
GeneProduct
241656 (Entrez Gene)
Pdgfa
GeneProduct
18590 (Entrez Gene)
Pdgfb
GeneProduct
18591 (Entrez Gene)
Pdgfra
GeneProduct
18595 (Entrez Gene)
Pdgfrb
GeneProduct
18596 (Entrez Gene)
Pfn1
GeneProduct
18643 (Entrez Gene)
Pik3c2a
GeneProduct
18704 (Entrez Gene)
Pik3c2b
GeneProduct
240752 (Entrez Gene)
Pik3c2g
GeneProduct
18705 (Entrez Gene)
Pik3c3
GeneProduct
225326 (Entrez Gene)
Pik3ca
GeneProduct
18706 (Entrez Gene)
Pik3cb
GeneProduct
74769 (Entrez Gene)
Pik3cd
GeneProduct
18707 (Entrez Gene)
Pik3cg
GeneProduct
30955 (Entrez Gene)
Pik3r1
GeneProduct
18708 (Entrez Gene)
Pik3r2
GeneProduct
18709 (Entrez Gene)
Pik3r3
GeneProduct
18710 (Entrez Gene)
Pik3r4
GeneProduct
75669 (Entrez Gene)
Pik3r5
GeneProduct
320207 (Entrez Gene)
Pip4k2a
GeneProduct
18718 (Entrez Gene)
Pip4k2b
GeneProduct
108083 (Entrez Gene)
Pip4k2c
GeneProduct
117150 (Entrez Gene)
Pip5k1a
GeneProduct
18720 (Entrez Gene)
Pip5k1b
GeneProduct
18719 (Entrez Gene)
Pip5k1c
GeneProduct
18717 (Entrez Gene)
Pip5kl1
GeneProduct
227733 (Entrez Gene)
Ppp1r12a
GeneProduct
17931 (Entrez Gene)
Ptk2
GeneProduct
14083 (Entrez Gene)
Pxn
GeneProduct
19303 (Entrez Gene)
Rac1
GeneProduct
19353 (Entrez Gene)
Rac1p2
GeneProduct
Rac2
GeneProduct
19354 (Entrez Gene)
Rac3
GeneProduct
170758 (Entrez Gene)
Rac4
GeneProduct
Raf1
GeneProduct
110157 (Entrez Gene)
Rassf7
GeneProduct
66985 (Entrez Gene)
Rdx
GeneProduct
19684 (Entrez Gene)
Rhoa
GeneProduct
11848 (Entrez Gene)
Rock1
GeneProduct
19877 (Entrez Gene)
Rock2
GeneProduct
19878 (Entrez Gene)
Rras
GeneProduct
20130 (Entrez Gene)
Rras2
GeneProduct
66922 (Entrez Gene)
Slc9a1
GeneProduct
20544 (Entrez Gene)
Sos1
GeneProduct
20662 (Entrez Gene)
Sos2
GeneProduct
20663 (Entrez Gene)
Ssh1
GeneProduct
231637 (Entrez Gene)
Ssh2
GeneProduct
237860 (Entrez Gene)
Ssh3
GeneProduct
245857 (Entrez Gene)
Tmsb4x
GeneProduct
19241 (Entrez Gene)
Vav1
GeneProduct
22324 (Entrez Gene)
Vcl
GeneProduct
22330 (Entrez Gene)
Vil1
GeneProduct
22349 (Entrez Gene)
Was
GeneProduct
22376 (Entrez Gene)
Wasf1
GeneProduct
83767 (Entrez Gene)
Wasf2
GeneProduct
242687 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Bibliography
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