Cell migration and invasion through p75NTR (Homo sapiens)

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1Ephrin BPcytoplasmInvasionDNAEphrinSTAT3ARF1BDNFNGFRPI3KEFNA2EFNA3TWIST1EFNB3EFNB1EFNA5AKT1EFNA1EFNB2AKT2EFNA4PARD3MMP8PAK1MMP9NTRK2TWIST1TRIORAC1MMP2JUNTIAM1RHOAADAMTS13KIDINS220EFNB2EFNB3EFNB1PCytoskeletonremodellingSTAT3PSTAT3PMMP2MMP9PCDH11RAC1PRAC1NGFRNTRK2BDNFAKT3AKT2AKT1AKT3DNACDH11nucleus


Description

p75NTR or NGFR (HGNC symbol) is an important factor regulating neuronal crest development and plays an important role in invasion and migration of neuronal cells during embryonic development.

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Ontology Terms

 

Bibliography

  1. Wislet S, Vandervelden G, Rogister B; ''From Neural Crest Development to Cancer and Vice Versa: How p75NTRand (Pro)neurotrophins Could Act on Cell Migration and Invasion?''; Front Mol Neurosci, 2018 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
107544view20:43, 18 October 2019Khanspersfixed unconnected
104090view10:23, 3 May 2019FehrhartModified description
104089view10:20, 3 May 2019Fehrhartwork in progress
103718view09:58, 29 March 2019DeSlUngrouped and grouped all groups, to test where RDF failure is comming from
103688view16:31, 28 March 2019Fehrhartwork in progress
103687view16:25, 28 March 2019FehrhartNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ADAMTS13GeneProductENSG00000160323 (Ensembl) ADAM13
AKT1GeneProductENSG00000142208 (Ensembl)
AKT2GeneProductENSG00000105221 (Ensembl)
AKT3GeneProductENSG00000117020 (Ensembl)
ARF1GeneProductENSG00000143761 (Ensembl)
BDNFGeneProduct627 (Entrez Gene) BDNF
CDH11GeneProduct1009 (Entrez Gene) Cadherin
EFNA1GeneProductENSG00000169242 (Ensembl)
EFNA2GeneProductENSG00000099617 (Ensembl)
EFNA3GeneProductENSG00000143590 (Ensembl)
EFNA4GeneProductENSG00000243364 (Ensembl)
EFNA5GeneProductENSG00000184349 (Ensembl)
EFNB1GeneProductENSG00000090776 (Ensembl)
EFNB2GeneProductENSG00000125266 (Ensembl)
EFNB3GeneProductENSG00000108947 (Ensembl)
JUNGeneProductENSG00000177606 (Ensembl)
KIDINS220GeneProductENSG00000134313 (Ensembl)
MMP2GeneProductENSG00000087245 (Ensembl)
MMP8GeneProductENSG00000118113 (Ensembl)
MMP9GeneProductENSG00000100985 (Ensembl)
NGFRGeneProductENSG00000064300 (Ensembl) p75NTR
NTRK2GeneProductENSG00000148053 (Ensembl)
PAK1GeneProductENSG00000149269 (Ensembl)
PARD3GeneProductENSG00000148498 (Ensembl)
PI3KGeneProduct
RAC1GeneProductENSG00000136238 (Ensembl)
RHOAGeneProduct387 (Entrez Gene) RhoA
STAT3GeneProduct6774 (Entrez Gene) STAT3
TIAM1GeneProductENSG00000156299 (Ensembl)
TRIOGeneProductENSG00000038382 (Ensembl)
TWIST1GeneProductENSG00000122691 (Ensembl)

Annotated Interactions

No annotated interactions

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