The human immune response to tuberculosis (Homo sapiens)

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This pathway is published in "The human immune response to tuberculosis and its treatment: a view from the blood" (PMID: 25703554).

Quality Tags

Ontology Terms



  1. Cliff JM, Kaufmann SH, McShane H, van Helden P, O'Garra A; ''The human immune response to tuberculosis and its treatment: a view from the blood.''; Immunol Rev, 2015 PubMed Europe PMC
  2. Berry MP, Graham CM, McNab FW, Xu Z, Bloch SA, Oni T, Wilkinson KA, Banchereau R, Skinner J, Wilkinson RJ, Quinn C, Blankenship D, Dhawan R, Cush JJ, Mejias A, Ramilo O, Kon OM, Pascual V, Banchereau J, Chaussabel D, O'Garra A; ''An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis.''; Nature, 2010 PubMed Europe PMC
  3. Cliff JM, Lee JS, Constantinou N, Cho JE, Clark TG, Ronacher K, King EC, Lukey PT, Duncan K, Van Helden PD, Walzl G, Dockrell HM; ''Distinct phases of blood gene expression pattern through tuberculosis treatment reflect modulation of the humoral immune response.''; J Infect Dis, 2013 PubMed Europe PMC
  4. Bloom CI, Graham CM, Berry MP, Rozakeas F, Redford PS, Wang Y, Xu Z, Wilkinson KA, Wilkinson RJ, Kendrick Y, Devouassoux G, Ferry T, Miyara M, Bouvry D, Valeyre D, Gorochov G, Blankenship D, Saadatian M, Vanhems P, Beynon H, Vancheeswaran R, Wickremasinghe M, Chaussabel D, Banchereau J, Pascual V, Ho LP, Lipman M, O'Garra A; ''Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers.''; PLoS One, 2013 PubMed Europe PMC


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101839view16:49, 12 November 2018EgonwReplaced an old Uniprot data source with the new one.
95608view12:10, 9 January 2018AndraModified description
95607view12:08, 9 January 2018AndraOntology Term : 'tuberculosis' added !
95606view12:07, 9 January 2018AndraAdded references
95605view11:57, 9 January 2018AndraInitial drawing of the pathway
95604view10:09, 9 January 2018AndraNew pathway

External references


View all...
NameTypeDatabase referenceComment
DRIP150ComplexO60244 (Uniprot-SwissProt)
IFI35GeneProductENSG00000068079 (Ensembl)
IFIT1GeneProductENSG00000185745 (Ensembl)
IFIT3GeneProductENSG00000119917 (Ensembl)
IFITM1GeneProductENSG00000185885 (Ensembl)
IFNAR1GeneProductENSG00000142166 (Ensembl)
IFNAR2GeneProductENSG00000159110 (Ensembl)
IFNGR1GeneProductENSG00000027697 (Ensembl)
IFNGR2GeneProductENSG00000159128 (Ensembl)
IRF1GeneProductENSG00000125347 (Ensembl)
IRF9GeneProductENSG00000213928 (Ensembl)
JAK1GeneProductENSG00000162434 (Ensembl)
JAK2GeneProductENSG00000096968 (Ensembl)
MX1GeneProductENSG00000157601 (Ensembl)
OAS1GeneProductENSG00000089127 (Ensembl)
PIAS1GeneProductENSG00000033800 (Ensembl)
PSMB8GeneProductENSG00000204264 (Ensembl)
PTPN2GeneProductENSG00000175354 (Ensembl)
SOCS1GeneProductENSG00000185338 (Ensembl)
STAT1GeneProductENSG00000115415 (Ensembl)
STAT2GeneProductENSG00000170581 (Ensembl)
TAP1GeneProductENSG00000168394 (Ensembl)
TYK2GeneProductENSG00000105397 (Ensembl)

Annotated Interactions

No annotated interactions

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