Phase II - Conjugation of compounds (Homo sapiens)

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1236, 926165, 132103647962, 689766, 69, 83, 89, 104...17, 5142, 120127, 128139, 140584, 14150, 63, 82713, 33, 34, 48, 12411039479937, 73, 100791, 40, 84223, 18, 29, 41, 114969, 14, 25, 27, 9324, 30, 14035, 45, 7521, 23, 70, 71, 1225972, 112499885, 12885, 127, 1281124, 47, 7419, 21, 23, 70, 71, 122107, 130, 13376, 818, 28, 1154, 1411, 40, 8419, 67, 135, 13872, 112, 12172, 11364, 94, 13978, 1023057, 87309591, 9354, 101, 13632, 676141643, 86, 111, 13712, 15, 44, 53, 1055, 10, 20, 36, 38...46, 802629931mitochondrial intermembrane spacemitochondrial matrixendoplasmic reticulum lumenendoplasmic reticulum lumenGolgi lumencytosolCNDP2:2Mn2+ dimerMg2+ ESD ATPSLC26A1 CYP1A2GCLM NHABP-SO4UGT3A2 SULT2A1 GSTT2B gGluCys6MPH2OCHAC1,2GSS GSTM1 MP+PAPSS1,2AdoHcySULT1A3 UGT1A3 UGT1A3,A4,A9O-centre functionalgroup substrateS-2-(hydroxyethyl)-glutathione N6AMT1 GlyAdoMetH2OE2SULT1E1,2A1SULT1B1 adenosine5'-monophosphateGGT dimersADPxenobiotic/medium-chain fatty acid:CoA ligasesSULT4A1 GlyESD dimerMTRR phenylacetylglutamineAc-CoANHABP UGT3A1 BMEGGT3P(381-568) Aflatoxin exo-8,9-oxide glutathione conjugate E1SSUAMTR PPiACSM2A NAT1 acetylatedconjugateMAT1A NADP+S-FGSHCHAC1 H+UGT1A1,4DAOSPNPBGSTM4 L-GluIMPAD1:Mg2+TPST1 GGT5(1-387) 6MPCDNBEtO NAT1GGT3P(1-380) O-glucuronideUDP-GlcUGT1A9 TPST2 UGTs (O-GlcAforming)NADP+PiT3SULT2A1 UDP-GlcAISNZ ACSM2B H+PPiUGT1A5 xenobiotic/medium-chain fatty acid:CoA ligasesCoA-SH27HCHOL3SH+MAT1A multimersH2OSULT1E1 electrophilicsubstrate:SGPhOHSULT2A1 ABHD14BNAcISNZ SLC35D1 hexamerGCLC electrophilicsubstrate:SGCDNB ATPE2-SO4GlyACSM1 BMGMGST3 GCTN4OGGSHGSSGH2ON6AMT1:TRMT112AdoMetE1SULT1A3 ATPH2OSULT2B1-2 methylarsoniteSULT1E1 dimerL-GluBEZ-CoAUGT2A1 3,3'-diiodothyronine4-sulfatePiUDP-GlcASULT1A1 N4-acetylsulfanilamide MMETOHNicotine N-glucuronide PiSULT1E1 taurolithocholateUGT1A4 SULTs active onpregnenoloneADPDSQ-OG NHABP NABQI GCTNDHEAPREGSGSTA5 SULT2B1-2 SO4(2-)UGT1A1tetramer,UGT1A4SULT1A4 NAT2UGT2B15 GLYAT-like proteinsH2OGSTT1 UGT1A1 SULT2B1-1 dimerSLC35D1 AcC-NAT1ADPGCLBUTH2OUGT2B10 UDP-GlcAPAPSDMAAUGP2 SULTs active onNH2AAFH2OUDP-GlcAPYUGT1A7 SULT1A2 arsenite(3-)SULT1A1,A2,C2,4A1GSTO1 SULT1C2 MAT2A NADHUGT1A3 AFXBO ABENZ TPMTGLYATL1 GLYATL3 SAMD N-hydroxy-4-aminobiphenyl O-acetylated conjugate electrophilicsubstrateUDP-GlcNAcNAT2 substrateH2OSULT2B1-1 G1PSULT1A3 UGT1A6 methylarsonateUDP-GlcADSQ PhOH UTPMPAGSTO1 SLC35B2 dimethylarsinateGLYATL2 GSTO2 SLC35B3 MGST1 AdoHcyH+PAPSS2 GSTA3 H2ONAD+GSTO1 dimerPAPSGSTK1 dimerGSTM5 GGT5(388-586) GSTA4 COMTN-hydroxy-2-acetylaminofluoreneUGT2B11 Salicylate-CoAthioester6MMPGGCT dimerH2OUGT1A4 ATPMTR SULT2B1-2 SULTs active on27HCHOLGSHTAM FAD APSNNMTGGCT AdoMetZn2+ FAD BDGAKR1A1SULT1A3,4 dimersNAT1 substrateGGT6(?-493) PARA-SO4Li+CysGlyUGT2B28 HIPAphenylacetyl-CoAASAL SULT1C4 AdoHcyUDPBILH2OOPLAH SLC26A2 PPiNAcPAB 8xUGP2GSS:Mg2+ dimerDNPSGABHD10AHCY LCAHCYSAMPMg2+ Ade-Ribcob(I)alamin AdoMetTMTNAcPAS Mg2+ UGT1A10Mg2+ CysGlyGSHUGT1A4 GSTT2 ATPFMN GSTM2 SULT2B1-1 AHCY:NAD+ tetramerO2CH2OBenzo(a)pyrene-7,8-diol 9,10-epoxide GSTA2 NABQI SULT2A1 CHAC2 DNPSG PPiATPOPROformateGSTK1 UGT2B7 GlcASULT1A1 TAMNG NAT2 acetylatedconjugateUGT1A1 MTRR:MTR(cob(I)alamin)ATPPhenyl glucuronate SALSULT6B1 NHABPMTRR SULT4A1 glutamine-N-acyltransferaseMMAIIICNDP2 PODXL2GLYAT 3,4DHBNZOSulf-Y97,118-PODXL2AS3MTK+ AdoHcyGGT6(1-?) UDPGGT7(1-472) CHOLH2OAMPAGAFMU SULTs active on DHEASULT1E1 Piadenosine5'-monophosphateSULT1C2 FMN AcC-NAT2BaPtDHDGSTA1 cholesterol sulfateACSM2B PAPSS1 NHABP UGT1A4 SULT dimers (T3)UGT2B4 SO4(2-)MeCbl UDPCoA-SHSULT1A1 dimerPhenyl sulfateUDPK+ ACSM2B-like proteinsATPadenosine5'-monophosphatePPiElectrophilicsubstrateSULT1E1 PREGTPST1,2CoA-SHtaurolithocholatesulfateSULT6B1 L-CysSULT2B1-1 ACSM2B UDP-GlcNAcSULT1C4 GGT1(1-380) TRMT112 adenosine5'-monophosphateN-hydroxy-4-aminobiphenyl O-glucuronide SULT1A1 GSTM3 HClGSTZ1 3,3'-diiodothyronineN-hydroxy-4-aminobiphenyl O-acetylated conjugate MGST2 PARAParaxanthine ACAP-OGLU Nicotine HPGDS ACSM1 ATPSULT1E1 NADPHDAphenylacetateACAP-GSH ATPACSM5 ACSM4 MAT2B SULT1E1 SULT1A2 OPLAHPiADPACAP-GSH UGT2B17 SULT dimers (T2)BPNT1BaP-7,8-dionePAPPNPUGT1A9 UGT1A1 27HCHOLNADPHL-MetAS3MT6xUGDHp-nitrophenolsulfateSLC26A1,2GSHGGT1(381-569) MGST trimersBENZA3,5,3'-triiodothyronine 4-sulfateBenzo(a)pyrene-7,8-diol-glutathione conjugate NAD+ Mn2+ GGT7(473-662) SULT1A1 PPiUGT2A3 CoA-SHL-GlnGSTP1 Acetaminophen (TN TYLENOL) SULT2B1-1 lithocholate sulfateSULT2A1 dimer6MMPSULT1B1 AAF-N-SSULT2A1 Zn2+ IMPAD1 N-centre functionalgroup substratePiSULT1C2 UGDH 3H,4MBNZMAT2B:MAT2A:K+:2Mg2+GST dimersDHEA-SO4PAPMTRR:MTR(MeCbl)N-glucuronideSLC35B2,3GSHH+UGT1A8 83, 11739439