Deubiquitination (Homo sapiens)

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15, 22, 32, 48, 52...28633, 57, 119411111623, 25, 31, 4612601143181, 1124029, 37, 83343, 21, 39, 109435347, 665518, 261071051045121061019, 596117681016, 84965462, 918145, 711728, 1202, 6742, 899858764950, 101959787, 11856, 1167, 4530704809, 13, 9444115185, 10361173699726579, 936271111010210864nucleoplasmcytosolmitochondrial matrixendosome lumenendoplasmic reticulum lumenRNF128,TRAF3,TRAF6,RHOA,TP53BABAM1 K63polyUb UBB(1-76) N6-glycyl-L-lysine-UBB(77-152) PSMD14 USP13 PolyUb-SNX3 STAM UBC(305-380) ADRM1:26Sproteasome:UCHL5BRCC3 K6polyUb UBC(609-684) KAT2B SHFM1 N6-glycyl-L-lysine-UBC(609-684) USP17L19 Ub-443-UBC(381-456) RPS27A(1-76) H2OUSP9X USP33 PSMD10 TAF10 RAD23B K27polyUb USP17L4 UBC(153-228) USP19 MAT2B ZRANB1 PSMB3 ATP OTUD3BAP1 PSMA8 PSMD8 K48polyUb Ub-367-UBC(305-380) UBB(153-228) H2OPSMC6 TNFAIP3 PSMB4 UBC(1-76) OTUB1,(OTUB2)PSMA1 RAD23B USP22 OTUB1 Histone H2B UBC(77-152) USP21 UBC(1-76) PolyUb-PTRH2 PSMD10 USP17:SUDS3USP42 USP25:DDX58OTUD5UBB(153-228) PSMC3 PSME1 USP17L22 UIMC1 N6-glycyl-L-lysine-UBB(1-76) H2OUSP24:DDB2PSMB8 PolyUb-VDAC2 H2OUSP7 UBB(77-152) N6-glycyl-L-lysine-RPS27A(1-76) BAP1:K48polyUb,K63polyUb-HCFC1PSMB7 K6polyUb RPS27A(1-76) PSMD11 UBC(305-380) UbUSP16 USP37:RUVLB1:PSMC5:CCNA1,CCNA2USP33:CCP110,ARRB1,ARRB2UbPSMC2 K33polyUb K63polyUbPSMB11 UBC(1-76) CYLDADRM1 RIPK1 USP17L10 SIAH2 USP26 K48polyUb CFTR Histone HIST2H2A Ub-595-UBC(533-608) H2OUSP4USP12 OTUB1 BIRC3 UbUSP17L24 PolyUb-DDX58 UBB(77-152) UBC(609-684) HIST3H2A Influenza A dsRNA intermediate form USP8 TAF9B PSME3 K6polyUb N6-glycyl-L-lysine-UBC(229-304) SHFM1 TNIP1 PSMD5 K6polyUb K63-UbH2OOTUD7AUBB(153-228) PSMD14 K27polyUb PolyUb-TP53 FOXK1 WDR48 UBB(77-152) PSMA5 PolyUb-TOMM20 MV dsRNA intermediate form PSMD4 TOMM20 YY1 STAM2 UBA52(1-76) UBC(609-684) PolyUb-ARRB2 USP4 PolyUb-MAT2B Ub-315-UBC(305-380) SMURF2 UBC(609-684) USP24 USP16 FOXO4 BABAM1 USP17L8 USP30 K11polyUb USP17L12 USP24 USP17:PolyUb-RCE1,PolyUb-CDC25A,PolyUb-DDX58,PolyUb-IFIH1PSMA5 HIST2H2BE PolyUb-DDX58 USP15 TP53 UBC(305-380) STAMBP:STAMPSMA7 TADA2B PTENK48polyUb UBB(77-152) GATA3 HGS USP9XK63polyUbBRE Ub-87-UBB(77-152) VCPIP1Ub-87-UBC(77-152) USP17L12 Ub-11-UBA52(1-76) USP15 USP10 PSMB2 OTUB1,(OTUB2):RNF128,TRAF3,TRAF6,RHOA,TP53USP17L18 USP19:HIF1A,BIRC2,BIRC3K63polyUb PSMB2 PSMB8 USP44 USP26 PSMF1 USP20 UCHL3 TRAF3 PSMB6 ADPARRB2 USP19 UCHL3 PTRH2 PSMC6 PSMC3 TNIP2 ATXN3 PolyUbMUL1 UBC(1-76) K63polyUb RUVBL1 BABAM1 UBB(1-76) USP17L22 K63polyUb Ub-391-UBC(381-456) USP17L12 PSMB9 K33polyUb UBC(457-532) USP17L1 TNIP1 UBC(153-228) PolyUb-TOMM70A UBC(1-76) p-4S,T185,T186-TGFBR1 UBA52(1-76) USP24 Ub-HIST3H2A K63polyUbUSP21 USP13UBB(77-152) polyUb-PARK2KAT2B ADRM1 PSMD10 Ub-139-UBC(77-152) 5'-ppp poly-U/UC RNA variants p-S131-VCPIP1USP17L24 OTUB1 Ub-histone H2APSME1 Ub-63-RPS27A(1-76) STAMBPL1Ub-163-UBC(153-228) K6polyUb HCFC1 ASXL1 Ub-histone HIST1 H2A PSMD12 USP8 ASXL2 K63polyUb UBB(1-76) SHFM1 NLRP3 USP17L18 RIPK1 UCHL3,SENP8:NEDD8(1-88)Ub-443-UBC(381-456) TFPT K6polyUb NEDD8(77-88)UBC(381-456) RAD23A UBC(153-228) PSMC5 Ub-519-UBC(457-532) K63polyUb-BECN1 UBC(457-532) USP44 PSMA1 PSMB9 Ub-SMAD4PSMD7 UBC(609-684) UBB(1-76) H2OCLSPN IDE UbPSMA3 USP13 USP8 Ub-543-UBC(533-608) UBC(381-456) IL33 UBC(609-684) BAP1:BAP1-interacting complexOTUB1,(OTUB2)UBC(457-532) UBC(229-304) USP4:PolyUb-TRAF2,PolyUb-TRAF6PSMA1 PSMB9 UBC(305-380) TGFB1 PolyUb-IDE RAD23BARD1 USP17L22 WDR20 USP17L21 USP24 Histone HIST1H2A INO80B H2OUb-619-UBC(609-684) PSME2 Influenza A dsRNA intermediate form USP28:CLSPN,MYCUCHL1 USP17L11 H2OPSMD5 K33polyUb USP11:NFKBIAUSP22 PSMA6 PSME3 CCNA1 K48polyUb,K63polyUb-HCFC1 UBC(305-380) YY1 UBC(609-684) UBC(229-304) K48polyUb OTUB2 Ub-139-UBB(77-152) PSMB7 Ub-histone HIST1H2B K63polyUbPolyUb-MDM4 UBC(77-152) PSMD2 p-S346,S367,S403-MDM4 USP17L5 USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,Ub-SMAD7:SMURF,Ub-KEAP1IKBKG USP44:CDC20PolyUbUBE2D1 K33polyUb TRAF6 Ub-RibC-AXIN:TNKS:RNF146OTUB2 USP25 PSMA2 VCP K29polyUb K11-UbPolyUb-MAP3K7 BRE H2OTRAF6 TGFB1:TGFBR2:Ub-p-TGFBR1:Ub-SMAD7:UCHL5/USP15PSMB4 K27polyUb PSMB1 USP17L13 BARD1UBA52(1-76) PSMD1 K33polyUb K63polyUb H2OUSP13:UFD1L:SKP2Ub-209-RIPK2 USP8:STAM2:HGSUSP21 K11polyUb USP18:MAP3K7:TAB1p-S406-FAM175A USP17L15 ATXN3L UBC(77-152) UbUBC(229-304) OTUD7B RPS27A(1-76) MDP K29polyUb USP12:WDR48:WDR20,USP26:ARZRANB1:K63polyUb-APCUSP17L15 PSMC1 UBB(1-76) UBB(77-152) UBC(305-380) Histone HIST1H2A UBA52(1-76) Ub-215-UBB(153-228) WDR20 ACTB(1-375) UBC(77-152) UBC(381-456) ACTR8 USP15:SMAD1,SMAD2,SMAD3,KEAP1,SMAD7:SMURF2:TGFBR1UBA52(1-76) K63polyUb-APC PSMA4 K48polyUb-RIPK1 PolyUbMV dsRNA intermediate form CDC20 TRAF6 ATXN3USP17L20 K29polyUb Ub-519-UBC(457-532) ADRM1 INO80 ZRANB1 UbK33polyUb K63polyUb-TRAF2 RNF128 Ub-467-UBC(457-532) PSMD14USP19UBC(229-304) Ub-671-UBC(609-684) ATP PAMP:NODoligomer:RIP2:NEMOUBC(1-76) UBC(457-532) K11polyUb UBC(77-152) HIST3H2A PSMA8 K63polyUbPSMD13 USP20 UBB(153-228) UBC(77-152) H2OUSP44:PolyUb-CDC20USP17L22 UBC(153-228) PSMD2 ATXN3PSMB2 OGT USP5:UbPSMB1 RPS27A(1-76) USP17L15 USP15 UBC(533-608) BAP1 USP10:PolyUb-SNX3,PolyUb-CTFRMBD6 Ub-SMAD2 TRRAP PolyUb-IL33 PolyUb-VDAC3 SMAD2 PSMD11 PSMA5 PSMB8 USP17L19 ATXN3 L-lysineUSP17L22 K11polyUb K33polyUb SMAD7 MAP3K7 N6-glycyl-L-lysine-UBC(305-380) USP17L1 PSMD9 USP21:PolyUb-GATA3,PolyUb-IL33K63polyUb-RIPK1 5'-ppp poly-U/UC RNA variants K63polyUb-APCK33polyUb UBB(153-228) K63polyUb-DDX58 Ub-163-UBB(153-228) viraldsRNA:IFIH1,viraldsRNA:K63polyUb-DDX58:MAVS:K63polyUb-TRAF3Ub-histone HIST2H2A AR PSMA7 UBC(381-456) UBC(153-228) TFPT USP49 PSMD14 K27polyUb INO80 complexUBC(153-228) BRISC complex:NLRP3K48-polyUb,K63-polyUbPolyUb-RHOT1 TNFAIP3:RIPK1USP3,SAGA:HistoneH2A,Histone H2BPSMD4 PSMC6 UCHL5:INO80 complexPSMB2 USP10,USP24,USP42:TP53PSMB9 K33polyUb UCHL3,SENP8:NEDD8MAVS UBC(305-380) Ub-63-UBA52(1-76) UBC(457-532) UCHL5 Ub-215-UBB(153-228) ESR1 PSMC1 TNIP2 USP16,USP21:Ub-histone H2AFOXK1 K29polyUb HGS USP17L11 UBC(381-456) UBC(533-608) K48polyUb UBC(457-532) NEDD8(1-88) Short K63polyUbUSP11 Ub-63-UBC(1-76) PSMD8 PSMD8 USP34UCHL1,UCHL3:Ub-LysUSP21 UBC(609-684) K63polyUb-TRAF3 USP47:POLBBAP1 UBA52(1-76) FOXK2 TRIM25 H2OASXL1 SKP2 BAP1USP20,USP33:PolyUb-ADRB2OGT UBC(533-608) USP17L18 viraldsRNA:IFIH1,viraldsRNA:K63polyUb-DDX58:MAVS:TRAF3Ub-671-UBC(609-684) PSMC2 Ub-histone H2A H2OBRCA1-AComplex:K63polyUb-histone H2AUBC(1-76) SIAH2:USP13PSMB7 USP17L12 K6polyUb H2OPSMB11 INO80E UBC(229-304) OTUD7B TRAF2 PSME1 TRAF2, TRAF6VDAC2 H2OBABAM1 USP17L5 PSMD3 K11polyUb USP17L22 Ub-KEAP1 p-S406-FAM175A PolyUbK29polyUb Ub-239-UBC(229-304) K48polyUb PSMD12 K63polyUbBARD1 USP37 USP10 EP300 TAB1 PSMD11 UBC(609-684) Ub-HIST3H2A PolyUbSNX3 CCNA2 PSMC1 TGFBR2 UBB(1-76) UBC(229-304) ATXN7 STAMUb-215-UBC(153-228) USP18:PolyUb-MAP3K7:TAB1RPS27A(1-76) Ub-histone H2B PSMC6 UBC(77-152) UFD1L:SKP2RNF146 OTUB1 UBB(77-152) PSMC3 PSMB6 PSMD6 FKBP8 TGFB1 K29polyUb RUVBL1 HIF1A K27polyUb UBE2D1,ESR1iE-DAP USP11:PolyUb-NFKBIAN6-glycyl-L-lysine-UBA52(1-76) H2OPSMA2 PolyUb-CLSPN USP17L15 OTUD7B,TNFAIP3,ZRANB1:K63polyUb-TRAF6IFIH1 UBC(609-684) K63polyUb H2OUSP17L10 PolyUbUSP19 K33polyUb USP30:PolyUb-MOMproteinsUSP10:SNX3,CTFRK29polyUb UBB(1-76) HCFC1 PSMD6 RPS27A(1-76) USP19:K63polyUb-RNF123SMAD4VCPHCFC1 INO80D PolyUb-NFKBIA UBB(1-76) SKP2 KDM1B USP17L8 UBC(533-608) HIST3H2A PSMA6 Ub-63-UBA52(1-76) YOD1ZRANB1K63-UbINO80 K27polyUb K33polyUb K63polyUb PSMC5 UBC(533-608) K11polyUb K63polyUb ACTR8 ATPPSMD2 UCHL3 UBC(533-608) K48polyUb FAM175B K63polyUb-DDX58 SMAD7 USP37 PSMB4 UBC(457-532) MDM2 UBC(229-304) RCE1 SENP8 K6polyUb IKBKG PolyUb-DDX58 PSMB7 Ub-HIST2H2BE NFRKB YOD1 UBA52(1-76) polyUb-PARK2 K48polyUb PSME2 H2OK63polyUb-DDX58UBC(153-228) K63polyUb H2OADRM1PolyUb-ADRB2 Ub-histone HIST2H2A UBB(1-76) Histone HIST2H2A UBB(77-152) K27polyUb FOXK1 PSMD8 UBC(153-228) UBB(153-228) K29polyUb USP16,USP22:HistoneH2APSMC1 DDX58PSMC4 PSMA1 PSMB1 BAP1-interactingcomplexNOD2 USP7 p-S166,S188-MDM2:p-S346,S367,S403-MDM4USP48 PSMD14 K33polyUb PSMA7 PolyUb-FOXO4 STAMBP RNF135 USP17L21 MBD5 MYSM1 PolyUb-AR UBB(77-152) UBC(533-608) PSMB10 UBC(153-228) VDAC1 USP17L11 H2ON6-glycyl-L-lysine-UBC(381-456) USP8:RNF128:OTUB1Ub-215-UBC(153-228) USP49 Ub-HIST3H2BB UBA52(1-76) HIST3H2BB PSMC3 H2OUSP17L13 Ub-SMAD4:USP9XRUVBL1 PSMD11 USP7:PolyUb-TP53,PolyUb-MDM2,PolyUb-MDM4,PolyUb-FOXO4,PolyUb-PTENUSP17L4 USP3 UBC(381-456) WDR48 H2OTRIM25 PAMP:NODoligomer:K63-polyUb-RIP2:NEMOTNFAIP3:K48polyUb-RIPK1FAM175B UBB(1-76) UFD1L UBB(77-152) UBB(153-228) USP2PSMA4 TNFAIP3 ESR1 PolyUb-FKBP8 K63polyUb TNIPsPSMD5 PolyUb-RIPK1 K63polyUbPSMF1 RHOT1 YOD1:VCPUSP17L3 UCHL5/USP15Ub-595-UBC(533-608) UBB(77-152) USP3 USP17L19 PolyUb-MUL1 K6polyUb PSMC2 Ub-histone HIST2H2A Ub-291-UBC(229-304) USP2:PolyUb,p-S166,S188-MDM2:PolyUb,p-S342,S367,S403-MDM4K63polyUb ARRB1 UBB(153-228) RibC-AXIN2 RibC-AXIN1 BIRC2 K63polyUb-SUDS3 UBC(457-532) K63polyUb-TRAF6 Ub-63-UBB(1-76) USP17L10 TRAF2 PSME4 PSMB3 TADA3 K63polyUb-TRAF6 OTUD7B,TNFAIP3,ZRANB1:K48polyUb-TRAF6PSMC2 UBC(1-76) USP19:RNF123N6-glycyl-L-lysine-UBC(1-76) SENP8 DDX58 USP47:PolyUb-POLBPSMB5 PolyUb-GATA3 UBB(153-228) K63polyUb PSMD3 UBC(305-380) UBB(77-152) INO80C PSMA4 K63polyUb-NLRP3 USP17L13 p-4S,T185,T186-TGFBR1 ACTL6A PSMA8 PolyUbZRANB1 TGFB1:TGFBR2:p-TGFBR1:Ub-SMAD7K29polyUb USP12:WDR48:WDR20,USP26:PolyUb-ARUBC(381-456) SMAD1