Role of Osx and miRNAs in tooth development (Homo sapiens)

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1let-7 miRNAsStimulationCementumCementoblastlithium chlorideMIR145RUNX2MIR29COSXKLF4DMP1DSPPBMP7NOTCH1NOTCH2NOTCH3NOTCH4ALPDKK1SOSTTCF-1CTNNB1MIR338MIR32MIR586MIR885MIR29AMIR34AMIRLET7A1MIR143MIR204MIR211DentinOdontoblastMIRLET7A2MIRLET7CMIRLET7DMIRLET7EMIRLET7F1MIRLET7F2MIRLET7GMIRLET7IMIR29B1MIR29B2mir-29 miRNAsInhibitionCrosstalkLegendBACCCCCCA, B, CCorresponds to pathway description


Description

Role of Osx and certain miRNAs in tooth development.

A – The role of Osx in dentinogenesis is shown by its regulation on Dspp.

B – Osx regulates the differentiation of cementoblasts through Wnt-β-catenin pathway.

C – Fine-tuning role of miRNA in tooth development.

Quality Tags

Ontology Terms

 

Bibliography

  1. Wang C, Liao H, Cao Z; ''Role of Osterix and MicroRNAs in Bone Formation and Tooth Development.''; Med Sci Monit, 2016 PubMed Europe PMC

History

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CompareRevisionActionTimeUserComment
91525view22:51, 8 March 2017KhanspersOntology Term : 'signaling pathway pertinent to development' added !
91524view22:50, 8 March 2017KhanspersOntology Term : 'odontoblast' added !
91523view22:50, 8 March 2017KhanspersOntology Term : 'cementoblast' added !
91522view22:49, 8 March 2017KhanspersModified description
91521view22:49, 8 March 2017KhanspersModified description
91520view22:49, 8 March 2017Khanspersadded specific areas corresponding to description
91519view22:44, 8 March 2017KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ALPGeneProductENSG00000162551 (Ensembl)
BMP7GeneProductENSG00000101144 (Ensembl)
CTNNB1GeneProductENSG00000168036 (Ensembl)
DKK1GeneProductENSG00000107984 (Ensembl)
DMP1GeneProductENSG00000152592 (Ensembl)
DSPPGeneProductENSG00000152591 (Ensembl)
KLF4GeneProductENSG00000136826 (Ensembl)
MIR143GeneProductMI0000459 (miRBase Sequence)
MIR145GeneProductENSG00000276365 (Ensembl)
MIR204GeneProductENSG00000207935 (Ensembl)
MIR211GeneProductENSG00000207702 (Ensembl)
MIR29AGeneProductENSG00000226380 (Ensembl)
MIR29B1GeneProduct407024 (Entrez Gene)
MIR29B2GeneProduct31620 (HGNC)
MIR29CRna31621 (HGNC)
MIR32GeneProductENSG00000207698 (Ensembl)
MIR338GeneProductENSG00000283604 (Ensembl)
MIR34AGeneProductENSG00000228526 (Ensembl)
MIR586GeneProductENSG00000207769 (Ensembl)
MIR885GeneProductENSG00000216135 (Ensembl)
MIRLET7A1GeneProductENSG00000199165 (Ensembl)
MIRLET7A2GeneProductENSG00000198975 (Ensembl)
MIRLET7CGeneProductENSG00000199030 (Ensembl)
MIRLET7DGeneProductENSG00000199133 (Ensembl)
MIRLET7EGeneProductENSG00000198972 (Ensembl)
MIRLET7F1GeneProductENSG00000199072 (Ensembl)
MIRLET7F2GeneProductENSG00000208012 (Ensembl)
MIRLET7GGeneProductENSG00000199150 (Ensembl)
MIRLET7IGeneProductENSG00000199179 (Ensembl)
NOTCH1GeneProductENSG00000148400 (Ensembl)
NOTCH2GeneProductENSG00000134250 (Ensembl)
NOTCH3GeneProductENSG00000074181 (Ensembl)
NOTCH4GeneProductENSG00000204301 (Ensembl)
OSXGeneProductENSG00000170374 (Ensembl)
RUNX2GeneProductENSG00000124813 (Ensembl)
SOSTGeneProductENSG00000167941 (Ensembl)
TCF-1GeneProductENSG00000135100 (Ensembl)
lithium chlorideMetaboliteCHEBI:48607 (ChEBI)

Annotated Interactions

No annotated interactions

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