Photodynamic therapy-induced NF-kB survival signaling (Homo sapiens)

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Photodynamic therapy may induce a pro-inflammatory and angiogenic response mediated by NF-κB.

Proteins on this pathway have targeted assays available via the CPTAC Assay Portal

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Ontology Terms



  1. Weijer R, Broekgaarden M, van Golen RF, Bulle E, Nieuwenhuis E, Jongejan A, Moerland PD, van Kampen AH, van Gulik TM, Heger M; ''Low-power photodynamic therapy induces survival signaling in perihilar cholangiocarcinoma cells.''; BMC Cancer, 2015 PubMed Europe PMC Scholia
  2. Broekgaarden M, Weijer R, van Gulik TM, Hamblin MR, Heger M; ''Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies.''; Cancer Metastasis Rev, 2015 PubMed Europe PMC Scholia


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106541view00:08, 6 September 2019KhanspersModified description
105514view06:04, 8 August 2019KhanspersModified description
88316view15:37, 1 August 2016FehrhartOntology Term : 'altered regulatory pathway' added !
88150view18:24, 26 July 2016AlexanderPicoModified title
86063view23:29, 28 June 2016KhanspersOntology Term : 'cancer' added !
85991view19:28, 22 June 2016KhanspersModified title
84547view19:15, 1 March 2016MaintBotTwo more groups
84546view19:14, 1 March 2016MaintBotConnected interactions and created groups
84535view20:08, 29 February 2016RuudweijerAdded reference.
84494view07:29, 26 February 2016RuudweijerModified title
84493view07:28, 26 February 2016RuudweijerModified description
84463view18:15, 25 February 2016RuudweijerNew pathway

External references


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NameTypeDatabase referenceComment
BCL2A1GeneProduct597 (Entrez Gene)
BCL2L2GeneProduct599 (Entrez Gene)
BIRC2GeneProduct329 (Entrez Gene)
BIRC3GeneProduct330 (Entrez Gene)
BIRC5GeneProduct332 (Entrez Gene)
CCND1GeneProduct595 (Entrez Gene)
CD40LGGeneProduct959 (Entrez Gene)
CFLARGeneProduct8837 (Entrez Gene)
CHUKGeneProduct1147 (Entrez Gene)
CSF2GeneProduct1437 (Entrez Gene)
CXCL2GeneProduct2920 (Entrez Gene)
EGLN2GeneProduct112398 (Entrez Gene)
ICAM1GeneProduct3383 (Entrez Gene)
IKBKBGeneProduct3551 (Entrez Gene)
IL1AGeneProduct3552 (Entrez Gene)
IL1BGeneProduct3553 (Entrez Gene)
IL2GeneProduct3558 (Entrez Gene)
IL6GeneProduct3569 (Entrez Gene)
IL8GeneProduct3576 (Entrez Gene)
MMP1GeneProduct4312 (Entrez Gene)
MMP2GeneProduct4313 (Entrez Gene)
MMP3GeneProduct4314 (Entrez Gene)
MMP9GeneProduct4318 (Entrez Gene)
NFKB1GeneProduct4790 (Entrez Gene)
NFKB2GeneProduct4791 (Entrez Gene)
PTGS2GeneProduct5743 (Entrez Gene)
RELGeneProduct5966 (Entrez Gene)
RELAGeneProduct5970 (Entrez Gene)
RELBGeneProduct5971 (Entrez Gene)
SELEGeneProduct6401 (Entrez Gene)
TNFGeneProduct7124 (Entrez Gene)
TNFRSF1AGeneProduct7132 (Entrez Gene)
TRAF6GeneProduct7189 (Entrez Gene)
VCAM1GeneProduct7412 (Entrez Gene)
VEGFAGeneProduct7422 (Entrez Gene)

Annotated Interactions

No annotated interactions

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