C-type lectin receptors (CLRs) (Homo sapiens)

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17, 10669, 1078, 3639, 419826, 83, 861, 5, 21, 35, 9510410522, 362, 14, 102802890, 1013667, 794, 30, 32, 76, 10311, 10025, 7318, 47, 63, 72, 9129, 8713, 8545, 56, 71, 10827, 5080106610524, 4358, 61, 643, 4412, 785414, 39, 1021024, 4361, 6233, 63, 74, 997, 7738, 75, 107408970963612, 56, 788720554272, 8110, 14, 15, 92, 931496, 3416, 60, 72775967, 7919, 31, 37, 49, 70...53, 65cytosolendoplasmic reticulum lumencytosolnucleoplasmCCL22 gene CLEC6A PAK2 p-Y65,Y76-FCER1G ITPR2 PSMC1 pathogens:CLEC6A,CLEC4E:FCER1G dimerHRAS Zn2+ PSMB1 PSMA6 PPP3CA Ca2+CLEC6A alpha-mannan CLEC4D:FCER1Gdimer:TDMNFKB1(1-433) p-T231-CARD9:BCL10:MALT1 oligomers:TRAF6PPP3CB PSMB7 p-T231-CARD9oligomer:BCL10p-Y15-CLEC7A CLEC7A:1,3-beta-D-glucanNFAT:CaN:CaMPSMB4 PSMD6 p-Y753,Y759-PLCG2UBE2N:UBE2V1UBE2D2 HRAS p-S177,S181-IKBKB PPip-14S-NFATC2 p-T231-CARD9:BCL10oligomersGalNAc-MUC21 p-S552-CARD11 MALT1:activecaspase-8PSMB2 PSMD14 I(1,4,5)P3 p-Y65,Y76-FCER1G TRAF6 oligomer PSMA7 Fe3+ NRAS MALT1 oligomer CLEC4A RELA p-T231-CARD9 oligomer p-S32,S36-NFKBIA alpha-mannan EP300 active caspase-8NFKB1(1-433) Ca2+ PPP3CB IkB(alpha):NF-kBcomplexp-S276-RELA p-S276-RELACLEC4D NFKBIA CLEC10A:Tn antigensCD209 GalNAc-MUC3B(?-901) CARD9ADPENV polyprotein p-T507,S645,S664-PRKCDMAP3K14PPP3R1 DAGsFCER1G Ub-200-UBC(153-228) ATPMAP3K7 PSMB9 PSMD6 TAB1 alpha-mannanCASP8(217-374) Ub-48-UBB(1-76) GalNAc-MUC3A HRAS GalNAc-MUC7 Ub-656-UBC(609-684) SKP1 p21 RAS:GTPRPS6KA5 PSMA1 KRAS GalNAc-MUC3A p-S276-RELA ADPUBC(77-152) GalNAc-MUC4(29-2169) GalNAc-MUC5AC CLEC4E:FCER1G dimerp-S257-NFATC1 p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TRIKA2RELA Ub-504-UBC(457-532) PSMB11 GalNAc-MUC13 RELA TAB1 AMPUb-48-RPS27A(1-76) TAB2 TDMalpha-mannan BTRC p-7S-p100 NFKB2(1-900) PYCARD NF-kB complexUBC(457-532) p21 RAS:GDPFCER1G SCF-beta-TRCPUb-200-UBC(153-228) PSMB11 FCER1G PSMB10 Ub-48-UBC(1-76) PI(3,4)P2 BCL10 oligomer p-T231-CARD9 oligomer DAGs:activep-T507,S645,S664-PRKCDGalNAc-MUC19(?-6254) EP300 CHUK:IKBKB:IKBKGI(1,4,5)P3CLEC4E p-T231-CARD9:BCL10oligomers:MALT1GalNAc-MUC7 K63polyUbp-T231-CARD9:BCL10:MALT1 oligomersPI(3,4,5)P3 KRAS GTP PPP3CA PSME2 PSMC5 PSMD2 H2OCALM1 p-S265-NFATC3 1,3-beta-D-glucan:p-Y15-CLEC7APSME2 GalNAc-MUCL1 alpha-mannan PSMC3 DAGs:p-T507,S645,S664-PRKCDNFKB1:p-S276-RELA:p300/CBPPPP3CA ATPUBC(153-228) CLEC4Ap-S338-RAF1 UBE2N pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:PLCG2p-S243-NFATC2 Ub-276-UBC(229-304) PDPK1 GalNAc-MUC4(29-2169) active p-T507,S645,S664-PRKCD ATPK63polyUbPSMB2 p-Y65,Y76-FCER1G p-T231-CARD9:BCL10:MALT1:TRAF6 oligomersActiveNIK:p-S176,180-IKKAdimer:p-7S-p100:RELBTAB1 PSMD14 CLEC4C:FCER1Gdimer:HIV gp120,HCVgp E2p-Y65,Y76-FCER1G PSME3 GDP PAK3 PSMD7 TAB1 PSMD10 Zn2+ PLCG2Ub-48-RPS27A(1-76) Calcineurin (CaN)PSMB3 p52:RELBADPRPS6KA5(MSK1/SAPK1):PKA catalytic subunitsp-S243-NFATC2 p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-p3Y,1S-TAK1PSME4 CLEC6A:FCER1Gdimer:alpha-mannanGalNAc-MUC15 UBB(1-76) CLEC6A ATPUb-48-UBA52(1-76) PSMD8 Protein Kinase A, catalytic subunits UBE2V1 TAB3 CHUK UBE2N:UBE2V1Pip-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomers:TAB1:TAB2/TAB3:K63polyUb-34,158-TAK1PSMD3 IL1B geneBCL10 oligomer Ac-CoAITPR3 ADPp-S276-RELA p-S177,S181-IKKB:IKKA:NEMORELA PSMA1 GalNAc-MUC5B(26-5703) CLEC6A TRAF6 GTP UBE2N p-S32,36-IkB-alpha:NF-kB complexTAB2 UbUb-48-UBA52(1-76) BCL10 oligomer PPiActiveNIK:p-S176,180-IKKAdimerCLEC6A Active NIK K48PolyUb-K21,22-p-S32,S36-IkBA ADPCLEC4E Active NIK NFKB1(1-433) Ub-48-UBB(1-76) ADPUBE2D1 p-T231-CARD9oligomerCASP8(385-479) PSMF1 TDM TAB2 CD209CALM1 TDM UBE2V1 CALM1 CLEC6A K63polyUbPSMB5 CLEC4E CD209:ManLAMBCL10 oligomer Ub-TRAF6 trimerbound to CBMcomplexp-T231-CARD9 oligomer RELB CoA-SHNFKB1(1-433) 1,3-beta-D-glucan CREBBP PLCG2alpha-mannan p-6Y-SYK PSMD10 FYN ATPManLAM MALT1 GalNAc-MUC12 Ub-124-UBC(77-152) RPS27A(1-76) PSMB5 PSMA7 CLEC4E Fe3+ IKKA dimerPSMC2 KRAS p-Y65,Y76-FCER1G GTP MALT1 oligomer PSMB8 UBC(305-380) ITPR2 PPP3CB UBE2V1 p-T231-CARD9 oligomer Ca2+ Ub-124-UBB(77-152) K48-polyUb-p-7S-p100 p-7S-p100 alpha-mannan UBC(229-304) PSMB1 SHFM1 DAGs CLEC4E MALT1 oligomer p21 RAS:GTP:RAF1PSMC5 PSMD8 ATPSRC-1TAB3 H2OATPNF-kB complexGalNAc-MUC15 ADPCLEC4C CHUK alpha-mannan MALT1oligomers:activecaspase-8:ASCBCL10 oligomer pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimerBCL10 oligomer ITPR:I(1,4,5)P3tetramerIKBKG 1,3-beta-D-glucanp-T231-CARD9 oligomer PAK1,2,3PSMD3 BCL10 UBA3p-T231-CARD9RELB UBB(153-228) CASP8(217-374) GalNAc-MUC1(24-1255) CREBBP PSME1 NFKB1(1-433) PSMA5 ITPR1 p52 PSMD13 K63polyUb-TRAF6 oligomer G76-NEDD8-C111-AcM-UBE2MCDC34 Ub-352-UBC(305-380) CLEC4D p-Y15-CLEC7A PSMD12 MALT1 oligomer PSMD1 GalNAc-MUC17 K63polyUb-NEMO RELB PSMB6 PSMD12 UBE2D2,UBE2D1,(CDC34)p-T231-CARD9 oligomer RAF1 ADPICAM2 PSMD11 CLEC4D:FCER1G dimerPSMB10 Active NIKNRAS RELB PSMC6 CD209:ICAM2BTRC HCV Genome polyprotein BCL10 oligomer K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complexUb-276-UBC(229-304) GalNAc-MUC17 FCER1G K63polyUb-TRAF6 TDM ATPCLEC4E:FCER1Gdimer:TDM,alpha-mannanpathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:SYKIL1B mRNA26S proteasomeNFKB2(1-900) ATPNFAT:CaN:CaMp-12S-NFATC1 GalNAc-MUC21 CD209 IP3 receptorhomotetramerAMPCREBBP p-S276-RELA:RELBPSMA5 p100:RELBPSMA3 GalNAc-MUC16 ADPRELB PSMC1 I(1,4,5)P3Ub-428-UBC(381-456) CD209:ICAM3:Ca+2MAP3K7 GalNAc-MUC5AC ADPICAM3 Ub-200-UBB(153-228) HRAS K63polyUb-TRAF6 oligomer UBB(77-152) Ca2+ ManLAMHCV Genome polyprotein RELB PhosphorylatedNFATC1,2,3p-S177,S181-IKKB:IKKA:pUb-NEMORELBZn2+ p-S338,Y340,Y341-RAF1 HCV Genome polyprotein EP300 PSME4 K63polyUb-34,158-TAK1 Ub-352-UBC(305-380) FCER1G CLEC7A Ub-656-UBC(609-684) p-T231-CARD9 oligomer IL1B(117-269)alpha-mannan ATPTDM PSMD13 Active NIK GalNAc-MUCL1 K63polyUb-TRAF6 oligomer I(1,4,5)P3 CHUK MALT1 UBE2N GalNAc-MUC2 UBC(609-684) PSMC6 CUL1 PSMB3 p-BCL10 SYK PLCG2 p-S176,S180-IKKA UBC(381-456) ITPR3 1,3-beta-D-glucan PSMB6 CARD9ADPPSMD1 GalNAc-MUC12 PSME3 PPP3R1 ITPR2 ATPGalNAc-MUC1(24-1255) PSMD11 p-Y753,Y759-PLCG2RELA PSMA8 NFKB1(1-433) p-13S-NFATC3 GTP p52 Ub-580-UBC(533-608) Ub-124-UBC(77-152) K63polyUb-TRAF6 oligomer NFKB1:p-S276,5AcK-RELA:p300/CBPCASP8(385-479) GTPPSMF1 PPP3CB alpha-mannan PSMC4 CCL17,CCL22 mRNAADPp-6Y-SYK ENV polyprotein SYKCUL1 ActiveNIK:p-S176,180-IKKAdimer:p100:RELBCLEC10APSMC4 CCL22 mRNA Tn antigensATPpathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYKMALT1 ATPHIV gp120,HCV gp E2PSMA3 GalNAc-MUC6(23-2392) ICAM3TRAF6TAB2 PSMD5 GalNAc-MUC20 GalNAc-MUC19(?-6254) FBXW11 CCL17 gene CREBBP, EP300SYK PSMD4 PAK1 FYN, LYNCLEC6A Ca2+ RELB CHUK p-T231-CARD9 oligomer 1,3-beta-D-glucan SYKFCER1G MALT1 oligomer AHCYL1 FCER1G Active NIK PSMB8 TDM PSMB4 MALT1NFKB1(1-433) CLEC7Ap52:RELBCLEC6A Ub-504-UBC(457-532) MALT1 oligomer PSMD5 SHFM1 FCER1G PSMC2 CLEC10A FBXW11 ADPTDM,alpha-mannanIL1B(1-269)PSMB7 CLEC4A:HIV gp120,HCVgpE2p21RAS:GTP:p-S338,Y340,Y341-RAF1PSMD4 CCL17 mRNA LYN LYN GalNAc-MUC13 PSMD7 TAB3 ITPR3 p-S276,5xAcK-RELA p-S176,S180-IKKA TAB3 DAGs KRAS PPP3R1 RAF1MALT1 CALM126S proteasomeFYN, LYNNRAS FYN CALM1 PSMA6 CASP8(385-479) p21RAS:GTP:p-S338-RAF1MALT1 oligomer GDPIL1B(1-116)PSMA2 p-T231-CARD9 oligomer PI(4,5)P2GalNAc-MUC20 NRAS K48-UbK63polyUb-34,158-p-T178,184,187,S192-TAK1 CD209 PSMD2 p-T231-CARD9:BCL10:MALT1:K63polyUb-TRAF6 oligomersIKBKB NAD+ ATPp-Y753,Y759-PLCG2 Zn2+ CALM1:4xCa2+IKBKG ICAM2UBC(1-76) UBC(533-608) Ca2+BCL10 oligomer ITPR1 TDM Ub-580-UBC(533-608) PSMB9 K48-polyUb-p-7S-p100:RELBPSMA2 PPP3CA Ub-200-UBB(153-228) K48-UbGalNAc-MUC3B(?-901) FCER1G PSMA8 KRAS pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:p-Y753,Y759-PLCG2Ca2+ ATPPSMA4 NFKB1(1-433) PSMD9 Calcineurin:Calmodulin (CaN:CaM)PSMA4 BCL10p-T507,S645,S664-PRKCD AHCYL1:NAD+:ITPR1:I(1,4,5)P3 tetramerUb-48-UBC(1-76) ADPPSMD9 PSMC3 Fe3+ p-S176,S180-IKKA TDM Ub-124-UBB(77-152) BCL10 oligomer PYCARDUBE2N:UBE2V1Ca2+TDM NRAS p-S257-NFATC1 ITPR1 CLEC4E RELB PPP3R1 Fe3+ CLEC4C 1,3-beta-D-glucan:p-Y15-CLEC7A:SYKUBA52(1-76) p-S177,S181-IKBKB CLEC4E p-T231-CARD9 oligomer CLEC4E ActiveNIK:p-176,S180-IKKAdimer:p-7S-p100:SCF-beta-TRCPGalNAc-MUC6(23-2392) TAB1:TAB2,TAB3:TAK1GalNAc-MUC16 p-S176,S180-IKKA TDM ENV polyprotein NFKB1:p-S276-RELACLEC4C:FCER1G dimerGalNAc-MUC5B(26-5703) CLEC6A:FCER1G dimerHRAS ATPPSME1 CCL17,CCL22 genesSKP1 p-S265-NFATC3 p-6Y-SYK Ub-428-UBC(381-456) CASP8(217-374) GalNAc-MUC2 82468152828452, 883452829752, 88979723, 48, 5751, 68