Selenium Micronutrient Network (Bos taurus)

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15472, 86, 129, 14825738, 25612911, 12, 65, 73, 116...17715492, 113, 143, 154109, 198195, 225, 23320316, 14698, 11631410960, 93, 143, 22885174ConversionProtein tyrosine nitrationTryptophan metabolismInhibitionCatalysisEnzymesLEGENDCofactorsOverarching processCofactor conversionGlycogenesisNecessary stimulationMicronutrientsInflammation and immune responseSelenoproteinsis composed ofNegative EffectProstaglandins metabolismOther proteinsLeukotriene metabolismStatusTranscription factorStimulationCa++ metabolismOxidative stressBiomarker forMetabolic stressReactionLipid peroxidationLipoprotein melabolismCleavageProcess or metabolism involved in Se PathwaySelenium statusFrom intracellular part to the plasmaMetabolitesBindingIntracellularNAD+ metabolismER protein foldingGlutathione metabolismDNA oxidationFolate metabolismPlasmaPGE2PGG2a-TocopherolPTGS1EPAPGH3PGE2Arachidonic acidPGE1DHAPGD2NFKB2Lipoxin A4Thromboxane B2ALAEPA8-Isoprostaglandin F2aPGF2aMDADHALipoxin B4Thromboxane A2DPA8-Isoprostaglandin F2aDPAPGI2Lipoxin B4Arachidonic acidLinoleic acidThromboxane B2Lipoxin A4ALAF2-IsoprostanePTGS2PGH2PGE1RELAPGE3PGI2F2-Isoprostanea-TocopherolLinoleic acidDGLAPGF2aPGD2NFKB1MDA11936, 101, 14523413, 11019, 120, 123, 144, 159...125, 20014598118125, 200182, 237145, 2671459923414549, 99131105858101145182, 23799101145, 18823412, 44, 58, 99, 118...7313234585813, 110999844, 99, 118, 119145, 186110145125, 20019, 120, 123, 159, 19058, 73, 118, 182, 237Kynurenine198MTR177, 206TXNRD1CBS53, 206IodineIodine264264KMO19815-HETEThyroxine (T4)Triiodothyronine (T3)5-HETER-Triiodothyronine (rT3)5-HETE15-HETER-Triiodothyronine (rT3)Thyroxine (T4)Triiodothyronine (T3)5,6-Epoxytetraene5-HPETE162, 264162, 264162, 26865, 73, 24423473, 23465, 73, 244162, 26465, 73, 244162, 268162, 26873NADP+CATMPOMPO154, 22743, 69, 113, 131113Uric acid38, 147CysteineF2PLGSERPINE1F7PLATPLGF7PLATGGT1F2SERPINE154223, 239239, 245545454239, 245231223, 2395454GPX 4TXNRD2XDH147, 169PRDX5H2O2ALOX15BALOX573, 14111, 104, 120, 140, 234CopperUric acid38, 147Vitamin B1279, 2195,10-Methylene-THFSelR92, 249Tryptophan109, 1985-methyl-THFSOD3PRDX1RFK222H2OGPX3NiacinamideCTH206PNPO31Heme3, 36, 53, 154, 227NADPHLipoic acid72ManganeseFAD235Methionine sulfoxide92Dehydroascorbic acid86, 152Leukotriene A4229, 266NADPHFAD235THFHydroxykynurenine198Folic acid177NADP+NADPHSeleniumSelenium105105SELENOKSep1593, 127, 14368GPX6GSH103Nicotinamidase109Calcium266Methionine92ManganeseNADPHFolic acid177FMN235SelenideSelenophosphateSelenocysteine148, 162148, 162148, 162CysteineLeukotriene C4Leukotriene C4231, 266GPX3209Dehydroascorbic acid86GPX2SelP71Trx-S272, 86, 129Ascorbic acid152Lipoic acid72PRDX4GPX 1NADP+HomocysteineROSRNS21, 24, 50, 56, 58...14, 154NADPHVitamin B1279, 219MTHFR177Homocysteine245DIO1SelHSEPHS2SELENOODIO3SELENOTSELENOSDIO2SELENOVSELENONSelPSELENOISELENOM56, 228, 23618017, 50, 71, 78162, 26445, 162, 26482, 85180180, 233162, 26260, 197, 204180, 195, 225180162, 264SOD1Pyridoxal 5'-phosphate198SerineIron266HypoxanthinePRDX3GSR25VLDLVLDL-TAGAPOBHDL-CLDLSAA3LDLRTAGoxLDLSAA4HDLVLDL-TAGSAA1SAA2ABCA1CholesterolHDL-CVLDLSERPINA3-7HDL/SAAAPOA1oxLDLHDL/APOA1SERPINA3-7FMNAPOA1HDLTAGSCARB1APOA1VLDL/APOBLDLAPOBCholesterol11243, 116, 144, 146, 22411216, 26114, 187, 20116, 2616112, 20811220143, 116, 146, 22416, 47235161643, 116, 146, 224161121616, 2643, 116, 144, 146, 224112114, 187, 2013516112112, 2081611216, 26, 4747161616, 26O298Pyridoxal 5'-phosphate1988-OHdGFAD8-OHdG174235174PRDX2ADPLeukotriene D4Leukotriene D4231ChlorineCopperChlorineCystathionineFAD235SOD2Dihydrolipoate72, 89SerineNADP+ATPZincNADP+GSSGNADPHZincNiacinLeukotriene B4Leukotriene B4229229, 266Quinolinic Acid109, 198PMPNOHOClNOO3NO2HNO269, 13169, 131NADP+GSH85, 103, 229FibrinogenICAM1TNFIL1BIL1BALBD-dimerICAM1HBAINSHbA1cIFNGFibrinIFNGFibrinogenCCL2HBGCCL2ALOX5APIFNGD-dimerIFNGCRPTNFFibrinINSRIL6ALBHbA1cIL6INS21, 185, 197, 24119754, 13955, 203, 208, 259, 2631975, 45, 7722655, 203, 259, 26355, 263784517, 45, 18588, 135, 1859077, 88, 116, 14410454, 13921, 7817, 197, 2412267890554, 22321, 7888, 135, 18590904554, 2235SELENOW83, 103, 155Riboflavin240SOD3256TXNRD1129Ascorbate86, 152O2-“XanthineCalcium266KYNU198Methionine92ADPTrx-(SH)272, 129ONOO-/ONOOHNitrotyrosineNitrotyrosine1414ATPLeukotriene E4Leukotriene E4231FructosamineLeukotriene F4GlucoseFructosamine22690, 203226183, 231Iron266HypoxanthineTXNRD3FLAD12, 222Ascorbic acid19, 152, 190