Apoptosis-related network due to altered Notch3 in ovarian cancer (Bos taurus)

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1NET1ERBB3APOETNFRSF10DTNFSQSTM1SERBP1CUL5RIPK2CUL1CDKN1AAKT1HSPB1CTNNA1HSPD1HELLSANXA5HDAC1NFKB1BCL3TRAF1NGFRAP1RNF7PTK2ETS1MAPK1CDKN1BRPS6KB1PPP2GBAXIN1SMAD7VIMPKN1IER3CSDACARD14NQO1GCLCJUNDF2RBIRC5THBS1TNFRSF21APPCASP7GGFBPP5ABL1PAK2SOCS3IL7RPTK2BVAV3ERN1GRP78


Description

Results of pathway analysis of apoptosis-related genes in OVCAR3 cells treated with Notch3 siRNA or control siRNA.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2864(79278) with a 96.0% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK; ''Notch3 pathway alterations in ovarian cancer.''; Cancer Res, 2014 PubMed

History

CompareRevisionActionTimeUserComment
80679view15:21, 30 June 2015MkutmonNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ABL1GeneProductENSBTAG00000017976 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:25
AKT1GeneProductENSBTAG00000017636 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:207
ANXA5GeneProductENSBTAG00000021746 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:308
APOEGeneProductENSBTAG00000010123 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:348
APPGeneProductENSBTAG00000017753 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:351
AXIN1GeneProductENSBTAG00000016577 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8312
BCL3ProteinENSBTAG00000009493 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:602
BIRC5GeneProductENSBTAG00000013573 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:332
CARD14GeneProductENSBTAG00000015261 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:79092
CASP7GeneProductENSBTAG00000006615 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:840
CDKN1AGeneProductENSBTAG00000008353 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1026
CDKN1BGeneProductENSBTAG00000018254 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1027
CSDAGeneProductENSBTAG00000009663 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8531
CTNNA1GeneProductENSBTAG00000014182 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1495
CUL1GeneProductENSBTAG00000008736 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8454
CUL5GeneProductENSBTAG00000012882 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8065
ERBB3GeneProductENSBTAG00000010444 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2065
ERN1GeneProductENSBTAG00000016799 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2081
ETS1GeneProductENSBTAG00000002341 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2113
F2RGeneProductENSBTAG00000020199 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2149
GCLCGeneProductENSBTAG00000015571 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2729
GGFBPP5GeneProductENSBTAG00000004150 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3084
GRP78GeneProductENSBTAG00000007662 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3309
HDAC1GeneProductENSBTAG00000012698 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3065
HELLSGeneProductENSBTAG00000005979 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3070
HSPB1GeneProductENSBTAG00000011969 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3315
HSPD1GeneProductENSBTAG00000012586 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3329
IER3GeneProductENSBTAG00000011358 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8870
IL7RGeneProductENSBTAG00000019975 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3575
JUNDGeneProduct
MAPK1GeneProductENSBTAG00000010312 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5594
NET1GeneProductENSBTAG00000007648 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10276
NFKB1GeneProductENSBTAG00000020270 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4790
NGFRAP1GeneProductENSBTAG00000006026 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:27018
NQO1GeneProductENSBTAG00000020632 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1728
PAK2GeneProductENSBTAG00000047856 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5062
PKN1GeneProductENSBTAG00000017037 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5585
PPP2GBGeneProduct
PTK2BGeneProductENSBTAG00000005958 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2185
PTK2GeneProductENSBTAG00000009578 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5747
RIPK2GeneProductENSBTAG00000015271 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8767
RNF7GeneProductENSBTAG00000002185 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9616
RPS6KB1GeneProductENSBTAG00000016851 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6198
SERBP1GeneProductENSBTAG00000012957 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:26135
SMAD7GeneProductENSBTAG00000012441 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4092
SOCS3GeneProductENSBTAG00000008441 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9021
SQSTM1GeneProductENSBTAG00000015591 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8878
THBS1GeneProductENSBTAG00000002006 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7057
TNFGeneProductENSBTAG00000025471 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7124
TNFRSF10DGeneProductENSBTAG00000047389 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8795
TNFRSF21GeneProductENSBTAG00000020054 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:27242
TRAF1GeneProductENSBTAG00000003012 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7185
VAV3GeneProductENSBTAG00000031575 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10451
VIMGeneProductENSBTAG00000018463 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7431

Annotated Interactions

No annotated interactions
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