Histone Modifications (Bos taurus)

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2154131Histone H3 GenesASH1LH3F3AH3K9acH3F3BHIST1H3AHIST1H3BHIST1H3CHIST1H3DHIST1H3EHIST1H3FHIST1H3GHIST1H3HHIST1H3IHIST1H3JHIST2H3AHIST2H3CHIST2H3DH3S10phH3R8ciH3K4me3H3K36me3H3K9me2/3H3K14acH3K18acH3K23acH3K36acH3K27me3DOT1LEHMT1BAT8EZH1EZH2KMT2AKMT2DKMT2CMLL4KMT2ENSD1PRDM2SETSETBP1SETD1ASETD1BSETD2SETD3SETD4SETD5SETD6SETD7SETD8SETD9SETDB1SETDB2SETMARSMYD1SMYD2SMYD3SMYD4SMYD5SUV39H1SUV39H2SUV420H1SUV420H2Histone H3/4 Lysine MethytransferasesEZH1EZH2EEDAEBP2PRC2-AEBP2 ComplexH4K20me3SUV420H1SUV420H2KMT2AKMT2DKMT2CMLL4SETD1ASETD1BCOMPASS ComplexSUV39H1SUV39H2Clr4 homologsSETD26Suv4-20h homologsH3K4me1H3K9me1H3K9acH3K27me1H3K27me2H3K79me1/2H3K79me3HIST1H4AH4K5acH4K8acH4K12acH4K16acH4K91acHIST1H4BHIST1H4CHIST1H4DHIST1H4EHIST1H4FHIST1H4GHIST1H4HHIST1H4IHIST1H4JHIST1H4KHIST1H4LHIST4H4Histone H4 Genes


Description

Histones can undergo many post-translational modifications that are involved in transcription regulation. This pathway provides an overview of various modifications for histones H3 and H4 and the enzymes that catalyze the modifications, where known.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2369(69927) with a 51.0% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

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  1. Wikipedians; ''''; http://en.wikipedia.org/wiki/Histone_methyltransferase,
  2. Rea S, Eisenhaber F, O'Carroll D, Strahl BD, Sun ZW, Schmid M, Opravil S, Mechtler K, Ponting CP, Allis CD, Jenuwein T; ''Regulation of chromatin structure by site-specific histone H3 methyltransferases.''; Nature, 2000 PubMed Europe PMC
  3. Krogan NJ, Dover J, Khorrami S, Greenblatt JF, Schneider J, Johnston M, Shilatifard A; ''COMPASS, a histone H3 (Lysine 4) methyltransferase required for telomeric silencing of gene expression.''; J Biol Chem, 2002 PubMed Europe PMC
  4. Kuzmichev A, Nishioka K, Erdjument-Bromage H, Tempst P, Reinberg D; ''Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein.''; Genes Dev, 2002 PubMed Europe PMC
  5. Schotta G, Lachner M, Sarma K, Ebert A, Sengupta R, Reuter G, Reinberg D, Jenuwein T; ''A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.''; Genes Dev, 2004 PubMed Europe PMC
  6. Strahl BD, Grant PA, Briggs SD, Sun ZW, Bone JR, Caldwell JA, Mollah S, Cook RG, Shabanowitz J, Hunt DF, Allis CD; ''Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.''; Mol Cell Biol, 2002 PubMed Europe PMC

History

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80674view15:21, 30 June 2015MkutmonNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AEBP2GeneProductENSBTAG00000010818 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000139154
ASH1LGeneProductENSBTAG00000003954 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116539
BAT8GeneProductENSBTAG00000005676 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10919
DOT1LGeneProductENSBTAG00000009996 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000104885
EEDGeneProductENSBTAG00000007847 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000074266
EHMT1GeneProductENSBTAG00000012148 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000181090
EZH1GeneProductENSBTAG00000021918 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000108799
EZH2GeneProductENSBTAG00000009426 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000106462
H3Protein
H3F3AGeneProductENSBTAG00000024561 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000163041
H3F3BGeneProduct
H4Protein
HIST1H3AGeneProduct
HIST1H3BGeneProduct
HIST1H3CGeneProduct
HIST1H3DGeneProductENSBTAG00000031766 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197409
HIST1H3EGeneProduct
HIST1H3FGeneProduct
HIST1H3GGeneProduct
HIST1H3HGeneProduct
HIST1H3IGeneProduct
HIST1H3JGeneProductENSBTAG00000031717 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197153
HIST1H4AGeneProduct
HIST1H4BGeneProduct
HIST1H4CGeneProductENSBTAG00000032259 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197061
HIST1H4DGeneProduct
HIST1H4EGeneProduct
HIST1H4FGeneProduct
HIST1H4GGeneProduct
HIST1H4HGeneProduct
HIST1H4IGeneProduct
HIST1H4JGeneProduct
HIST1H4KGeneProduct
HIST1H4LGeneProduct
HIST2H3AGeneProduct
HIST2H3CGeneProduct
HIST2H3DGeneProduct
HIST4H4GeneProduct
KMT2AGeneProductENSBTAG00000018093 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000118058
KMT2CGeneProductENSBTAG00000024199 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000055609
KMT2DGeneProductENSBTAG00000014429 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000167548
KMT2EGeneProductENSBTAG00000009207 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000005483
MLL4GeneProduct
NSD1GeneProductENSBTAG00000025426 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000165671
PRDM2GeneProductENSBTAG00000020552 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116731
SETBP1GeneProductENSBTAG00000018088 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000152217
SETD1AGeneProductENSBTAG00000002345 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000099381
SETD1BGeneProductENSBTAG00000004172 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000139718
SETD2GeneProductENSBTAG00000002948 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000181555
SETD3GeneProductENSBTAG00000018310 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000183576
SETD4GeneProductENSBTAG00000018682 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000185917
SETD5GeneProductENSBTAG00000019193 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000168137
SETD6GeneProductENSBTAG00000020781 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000103037
SETD7GeneProductENSBTAG00000003581 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000145391
SETD8GeneProductENSBTAG00000000139 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000183955
SETD9GeneProductENSBTAG00000013426 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000155542
SETDB1GeneProductENSBTAG00000000098 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000143379
SETDB2GeneProductENSBTAG00000007329 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000136169
SETGeneProductENSBTAG00000020959 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000119335
SETMARGeneProductENSBTAG00000018935 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000170364
SMYD1GeneProductENSBTAG00000021120 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000115593
SMYD2GeneProductENSBTAG00000013166 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000143499
SMYD3GeneProductENSBTAG00000033180 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000185420
SMYD4GeneProductENSBTAG00000009708 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000186532
SMYD5GeneProductENSBTAG00000008764 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000135632
SUV39H1GeneProductENSBTAG00000004706 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000101945
SUV39H2GeneProductENSBTAG00000010210 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000152455
SUV420H1GeneProductENSBTAG00000001185 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000110066
SUV420H2GeneProductENSBTAG00000014087 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000133247

Annotated Interactions

No annotated interactions
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