G13 Signaling Pathway (Mus musculus)

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1Activated Rho AActin PolymerizationFilopodia FormationMembraneRufflingActin PolymerizationDisassembly of ActinAnti-ApoptoticCytokinesisStress FiberDisappearanceActin ReorganizationCell-Cell AdhesionContraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber ContractionArhgef1RtknArhgdigSra1Pik3cdMap3k4Pik3cbDiap1MybphCfl1Pik3caPip4k2aCfl2Sh3rf1Pkn1Limk1Ppp1cbIqgap2Cdc42Rhpn2RhoaGna13Mapk10Rock1ArhgdibPak3WasPfn1Rac1Rps6kb1Myl1Pik3r2Tnk2CitIqgap1Rock2WaslCalm1


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP524(r21780) with a 89% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
79200view08:23, 10 March 2015EgonwConnected dots and minor H/Z reallignment of nodes.
75845view23:21, 10 June 2014Khanspersimproved layout
71281view04:21, 17 October 2013MaintBotRemoved buggy complexes
69202view18:24, 8 July 2013MaintBotUpdated to 2013 gpml schema
67276view10:30, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
41392view00:29, 2 March 2011MaintBotRemoved redundant pathway information and comments
35413view10:29, 12 February 2010Thomasfixed sra1 xref
35411view10:26, 12 February 2010ThomasModified description
35409view10:25, 12 February 2010Thomasadded literature
32958view20:39, 28 September 2009MaintBotAdded xrefs
32390view16:58, 15 August 2009MaintBotFixed text labels
32034view13:27, 14 August 2009MaintBotFixed group labels
31425view20:59, 13 August 2009MaintBotFixed text labels
30895view00:22, 30 July 2009MaintBotConverted from Homo sapiens
21307view11:31, 14 November 2008MaintBot[[Pathway:Mus musculus:G13 Signaling Pathway]] moved to [[Pathway:WP298]]: Moved to stable identifier
8066view13:46, 7 January 2008MaintBot[[Pathway:Mouse:G13 Signaling Pathway]] moved to [[Pathway:Mus musculus:G13 Signaling Pathway]]: Renaming species
7655view16:07, 18 December 2007MaintBotfixed category names
7230view12:41, 4 November 2007MaintBotAdded categories to GPML
6444view22:18, 22 May 2007A.Chowgpml file for [[Mouse:G13_Signaling_Pathway]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ArhgdibGeneProduct11857 (Entrez Gene)
ArhgdigGeneProduct14570 (Entrez Gene)
Arhgef1GeneProduct16801 (Entrez Gene)
Calm1GeneProduct12313 (Entrez Gene)
Cdc42GeneProduct12540 (Entrez Gene)
Cfl1GeneProduct12631 (Entrez Gene)
Cfl2GeneProduct12632 (Entrez Gene)
CitGeneProduct12704 (Entrez Gene)
Diap1GeneProduct13367 (Entrez Gene)
Gna13GeneProduct14674 (Entrez Gene)
Iqgap1GeneProduct29875 (Entrez Gene)
Iqgap2GeneProduct544963 (Entrez Gene)
Limk1GeneProduct16885 (Entrez Gene)
Map3k4GeneProduct26407 (Entrez Gene)
Mapk10GeneProduct26414 (Entrez Gene)
MybphGeneProduct53311 (Entrez Gene)
Myl1GeneProduct17901 (Entrez Gene)
Pak3GeneProduct18481 (Entrez Gene)
Pfn1GeneProduct18643 (Entrez Gene)
Pik3caGeneProduct18706 (Entrez Gene)
Pik3cbGeneProduct74769 (Entrez Gene)
Pik3cdGeneProduct18707 (Entrez Gene) P42338
Pik3r2GeneProduct18709 (Entrez Gene)
Pip4k2aGeneProduct18718 (Entrez Gene)
Pkn1GeneProduct320795 (Entrez Gene)
Ppp1cbGeneProduct19046 (Entrez Gene)
Rac1GeneProduct19353 (Entrez Gene)
RhoaGeneProduct11848 (Entrez Gene)
Rhpn2GeneProduct52428 (Entrez Gene)
Rock1GeneProduct19877 (Entrez Gene) S69211
Rock2GeneProduct19878 (Entrez Gene) BAA31594
Rps6kb1GeneProduct72508 (Entrez Gene) A41687
RtknGeneProduct20166 (Entrez Gene)
Sh3rf1GeneProduct59009 (Entrez Gene) Posh
Sra1GeneProduct24068 (Entrez Gene)
Tnk2GeneProduct51789 (Entrez Gene) S33596
WasGeneProduct22376 (Entrez Gene)
WaslGeneProduct73178 (Entrez Gene)

Annotated Interactions

No annotated interactions
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