Interactome of polycomb repressive complex 2 (PRC2) (Homo sapiens)

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1Interaction identified by multiple replicatesPRC2LegendMTF2ELLJMJTRIM35STK38THRAP3BCLAF1STK38SETXMORC32Interaction identified by few replicatesPreviously identified interactionRBBP7AEBP2EZH2EEDSUZ12EZH1RBBP4


A proposed interactome of Polycomb repressive complex 2 (PRC2), based on proteomics.

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Ontology Terms



  1. Shen X, Kim W, Fujiwara Y, Simon MD, Liu Y, Mysliwiec MR, Yuan GC, Lee Y, Orkin SH; ''Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.''; Cell, 2009 PubMed
  2. Bracken CP, Wall SJ, Barré B, Panov KI, Ajuh PM, Perkins ND; ''Regulation of cyclin D1 RNA stability by SNIP1.''; Cancer Res, 2008 PubMed


88672view15:36, 12 August 2016JmeliusOntology Term : 'regulatory pathway' added !
87379view11:05, 22 July 2016MaintBotadded missing graphids
79908view21:10, 24 April 2015KhanspersModified description
79907view21:03, 24 April 2015KhanspersNew pathway

External references


View all...
NameTypeDatabase referenceComment
AEBP2GeneProductENSG00000139154 (Ensembl)
BCLAF1GeneProductENSG00000029363 (Ensembl)
EEDGeneProductENSG00000074266 (Ensembl)
ELLGeneProductENSG00000105656 (Ensembl)
EZH1GeneProductENSG00000108799 (Ensembl)
EZH2GeneProductENSG00000106462 (Ensembl)
JMJGeneProductENSG00000008083 (Ensembl)
MORC3GeneProductENSG00000159256 (Ensembl)
MTF2GeneProductENSG00000143033 (Ensembl)
RBBP4GeneProductENSG00000162521 (Ensembl)
RBBP7GeneProductENSG00000102054 (Ensembl)
SETXGeneProductENSG00000107290 (Ensembl)
STK38GeneProductENSG00000112079 (Ensembl)
SUZ12GeneProductENSG00000178691 (Ensembl)
THRAP3GeneProductENSG00000054118 (Ensembl)
TRIM35GeneProductENSG00000104228 (Ensembl)

Annotated Interactions

No annotated interactions

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