Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Homo sapiens)

From WikiPathways

Revision as of 13:43, 16 August 2017 by ReactomeTeam (Talk | contribs)
Jump to: navigation, search
2333, 51163, 27, 284, 12, 213412219454025929, 492124, 267, 151830237, 4895, 34343622, 30, 471734316, 38, 42919, 438, 10, 1135, 4314cytosolmitochondrial matrixSiO2 K63polyUb ADPprgJ p-T180,Y182-MAPK14 TRAF6 MAPK14 NLRP3 ATP TNFAIP3p-S176,S180-IKKA MDP UBE2V1 NOD1 Phospho-p38 MAPK2xHC-TXN P2RX7 ATP:P2X7oligomer:Pannexin-1UBE2N K63polyUb K63polyUbNOD1BIRC2 TXN MDP NOD2 PAMP:NODoligomer:K63-polyUb-RIP2:NEMO:TAK1 complexNOD1:iE-DAP oligomerCHUK:IKBKB:IKBKGTXNIPNOD2 PYCARD ATP:P2X7Ub-209-RIPK2 HUA NLRP1NLRP3 elicitorproteins2xHC-TXNPAMP:NODoligomer:RIP2:K63-pUb-K285-NEMOATP CASP1(1-404)SUGT1PANX1HSP90AB1 TAK1 complexIKBKG NOD1 CARD9 PYCARDNLRP1 ATPOxidizedthioredoxin:TXNIPNOD1 NLRP1 SUGT1 P2RX7 TRAF6 E3/E2ubiquitin ligasecomplexMDPMAPK13 Ub-209-RIPK2 ITCH NOD2 BCL2 CASP2(2-452) RIP2 ubiquitinligasesNLRP3elicitors:NLRP3oligomer:ASCTAB3 CASP8(1-479) p-T180,Y182-MAPK11 TAB1 RIPK2 SUGT1 Ub-285-IKBKG PAMP:NODoligomer:RIP2HUA NOD1 iE-DAPSiO2 NOD1:iE-DAP:Longprodomain caspasesROSBIRC3 PYCARD NOD1:iE-DAPNOD1 NOD2 NLRP3 elicitors:NLRP3 oligomer iE-DAP MAP2K6IKBKG Flagellin BCL2L1 TAK1 complexTAB3 IKBKB IKBKG CYLDNOD2 MDP HSP90AB1 dsDNA:AIM2 oligomer CASP1(1-404) PSTPIP1 trimerNLRP3MDP:NLRP1P2RX7 MDP MAP3K7 TAB3 NLRP3elicitors:NLRP3iE-DAP ATP CASP1(1-404) MDP:NOD2MDP MDP Long prodomaincaspasesCASP1(1-404) NLRP3 NLRP3 elicitorproteins:NLRP3MDP:NLRP1:ATPActivated TAKcomplexesIKBKGCASP4(?-377) PANX1 CASP4(?-377) CASP1(1-404) NLRP3 PYCARD prgJ p-2S,S376,T,T209,T387-IRAK1 CARD9ATP:P2X7 oligomerTXNIP CHUK IKBKG MAPK12 iE-DAP NOD1 TAB3 dsDNA:AIM2oligomer:ASC:Procaspase-1IPAFelicitors:NLRC4:Procaspase-1p-T183,Y185-MAPK12 iE-DAP NOD1 iE-DAP TAB1 MDP K+TAB2 NOD2 TAB2 Asb TXNIP TXNNOD1 NLRC4 K63polyUb NOD1 MDP p-S207,T211-MAP2K6MAP3K7 HSP90AB1dsDNA:AIM2 oligomer NLRP3elicitors:NLRP3oligomerIKBKG Bcl-2/Bcl-X(L)TAB2 p-T184,T187-MAP3K7 CASP8(1-479) ATPATP iE-DAP RIPK2 PAMP:NODoligomer:RIP2:CARD9PAMP:NODoligomer:K63-polyUb-RIP2:NEMOK63polyUb K63polyUb-TRAF6 RIPK2Flagellin BCL2L1 PYCARD NLRP3elicitors:NLRP3oligomer:ASC:Procaspase-1PSTPIP1 trimer:PyrintrimerMDP:NOD2 oligomerNOD2 PAMP:NODoligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complexTAB3 NOD2 p-T180,Y182-MAPK13 Double-stranded DNAMAP3K7 CASP9(1-416) NLRP3 Alpha-hemolysin Asb APP(672-711) MDP MAP3K7 MAP3K7 AIM2 TXNIP:NLRP3AIM2Pyrin trimer:ASCNLRP3 elicitor smallmolecules:NLRP3Flagellin Ub-209-RIPK2 Bcl-2/Bcl-X(L):NLRP1NLRP3 elicitor smallmoleculesPyrin trimerPAMP:NOD oligomerNOD2 NLRC4prgJ ATPIPAF elicitors:NLRC4NLRP1 NOD1 MAPK11 TAB2 MEFV TXNIP SUGT1 NOD2Double-stranded DNA NOD1 Alpha-hemolysin MDP PSTPIP1 ATPActivated IKKComplexp38 MAPKIPAF elicitorsAsb P2RX7MDP SUGT1:HSP90ADPAPP(672-711) PAMP:NODoligomer:RIP2:NEMONLRP3 elicitors:NLRP3 oligomer iE-DAP TAB1 dsDNA:AIM2iE-DAP TRAF6 HSP90AB1 NOD1 BCL2 TAB2 SUGT1 NOD2 PSTPIP1 TAB1 iE-DAP IKBKG CASP1(1-404) HSP90AB1 MDP HUA MEFV Alpha-hemolysin p-IRAK2 MEFV UBE2V1 K63polyUb iE-DAP NLRC4 RIPK2 UBE2N UBE2N Thioredoxin:TXNIPp-S177,S181-IKBKB iE-DAP APP(672-711) TAB1 MDP iE-DAP dsDNA:AIM2oligomer:ASCdsDNA:AIM2 oligomerSiO2 K+RIPK2 NLRP3:SUGT1:HSP90NOD2 CASP9(1-416) CASP2(2-452) IKBKG UBE2V1 NLRP3 Ub-209-RIPK2 MDP:NLRP1:ATPoligomerPYCARD 13, 41, 44, 5020, 32, 4620, 4613, 44, 5039