Fc epsilon receptor (FCERI) signaling (Homo sapiens)

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16, 50127, 132, 14214812412, 48, 61, 78, 83...3, 1457323, 36, 90, 9251, 97, 14768, 693, 70, 12917, 712, 6, 1336622, 80, 108, 14512163, 12855, 11858, 84, 99, 12680, 122, 1431259, 106, 123, 133107, 11511781, 93, 14037, 6713158, 12647, 527549, 56, 74141431, 35, 82, 9895, 10134, 6033, 41, 102130, 1418, 10, 18, 39, 541527, 110, 135, 14442, 91, 12964, 65, 109, 1111, 14, 20, 72, 13631, 139, 1469, 6213, 77, 11911, 2440, 727, 25, 8638, 53, 76, 10446, 94, 14438, 53, 76, 10419, 21, 45, 85, 87cytosolnucleoplasmendoplasmic reticulum lumenIg heavy chain V-I region HG3 IGLV(23-?) Ig heavy chain V-III region BRO Ig lambda chain V-II region MGC I(1,4,5)P3p-S177,S181-IKBKB p-S32,S36-NFKBIA Ig kappa chain V-I region AG RELA PSMD3 IGLC3 IGKV4-1(21-?) IGHE Ig lambda chain V-IV region Kern PPiDAG:p-5Y-PKC-theta:p-S552,S645-CARMA1 oligomerp-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCGp-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3ITPR3 PSMB8 Ig lambda chain V-II region BOH Ig heavy chain V-I region HG3 p-12S-NFATC1 ADPDAGs TAB3 PI3KIGLC2 MAPK8 Ig lambda chain V-III region SH GTP Ig lambda chain V-VI region AR SKP1 IGLV4-69(1-?) Ig heavy chain V-III region DOB IGLV1-44(1-?) I(1,4,5)P3 Fe3+ IGLC1 ADPJUNIGKV1-5(23-?) p-FCERI aggregate p-Y239,Y240,Y317-SHC1-2 p-S271,T275-MAP2K7 p-10Y-LAT2 IGLV2-11(1-?) ATPIg lambda chain V-I region VOR Ig lambda chain V-IV region Kern GRB2-1 IGLV8-61(1-?) CHUK AllerginCa2+ GTPIg kappa chain V-III region POM K63polyUb-TRAF6 Ig heavy chain V-III region CAM IGHE PI(3,4,5)P3 IGLV3-16(1-?) Ig kappa chain V-II region Cum p-FCERI aggregate UBE2N:UBE2V1Ig lambda chain V-I region NEW SOS1 IGLC1 p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76p-Y90,T219,T538,S676,S695-PRKCQ Ig kappa chain V-III region B6 Ig heavy chain V-I region EU NRAS Ig kappa chain V-I region HK101 GRB2-1 Ig kappa chain V-II region RPMI 6410 ADPp-Y113,128,145-LCP2 RELA Ig lambda chain V-I region HA DAGs IGLV5-45(1-?) Ig kappa chain V-II region FR IKBKG PhosphorylatedNFATC1,2,3Clusteredp:LYN:p-FCERI:IgE:allergin:p-6Y-SYKTAB1 Ig kappa chain V-I region DEE p-MAPK8/9/10Ig lambda chain V region 4A Ig lambda chain V-II region BOH p-Y239,Y240,Y317-SHC1-2 PPP3CB SOS1 p-CARMA1 oligomer CALM1 GAB2 Ig lambda chain V region 4A p-S63,S73-JUN H2OIg lambda chain V-III region LOI Ig heavy chain V-II region WAH Ig heavy chain V-II region OU p-Y91,Y420-TXK Ig heavy chain V-III region BRO IGLV3-12(1-?) Allergin GRAP2 p-Y223,Y551-BTK Zn2+ IGKV1-5(23-?) Ig lambda chain V-III region SH IGLV10-54(1-?) p-S552,S645-CARD11MAP3K7 Ig kappa chain V-II region Cum p-T325,T331,S362,S374-FOS Ig kappa chain V-I region Daudi Ig kappa chain V-I region HK101 Ig kappa chain V-I region AU IgH heavy chain V-III region VH26 precursor PI(3,4,5)P3 PSMC6 Ig lambda chain V-I region HA GDP PSME4 HRAS PSMA2 GRAP2 UBE2N:UBE2V1IGKV1-12 IGLV3-27(1-?) Ig kappa chain V-II region FR GRAP2 PLCG2 p-Y172-VAV2 PPP3CB p-Y239,Y240,Y317-SHC1-2 DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 oligomerp-S552,S645-CARD11 ADPATPIg heavy chain V-II region NEWM IGLV4-3(1-?) IGHV7-81(1-?) VAV3 p-S552-CARD11 IgH heavy chain V-III region VH26 precursor Allergin:p-LYN:p-FCERI:IgE aggregateIGLC7 GRAP2 PLCG2 Allergin ITPR3 PLCG1 IGKC RASGRP1 IGLV3-22(1-?) FCERI:IgE:allerginaggregateUb-656-UBC(609-684) Ig lambda chain V region 4A IGLV4-60(1-?) IGKV3D-20 p-T325,T331,S362,S374-FOSIg kappa chain V region EV15 Ig kappa chain V-I region Daudi ITPR:I(1,4,5)P3tetramerIGLV3-22(1-?) Ig heavy chain V-III region WEA IGHV1-2 FCERI:IgE aggregate IGKC BCL10 oligomer Ig kappa chain V-III region VG p-Y396-LYNp-Y239,Y240,Y317-SHC1-2 Ig heavy chain V-III region CAM NAD+ IGLV2-23(1-?) IGKV2-28 Ig heavy chain V-III region DOB p-Y239,Y240,Y317-SHC1-2 PI(3,4,5)P3 Ub-428-UBC(381-456) p-CARMA1 oligomer Ig lambda chain V-III region SH Ig lambda chain V-I region NEWM Ig lambda chain V-I region VOR Ig kappa chain V-II region FR Clusteredp:LYN:p-FCERI:IgE:allergin:SYKIGLV10-54(1-?) IGKV2D-30 IGKC IGHV1-2 IGLV3-27(1-?) Ig kappa chain V-II region RPMI 6410 IGLV3-12(1-?) IGLV2-18(1-?) MAPK9 IGLV8-61(1-?) p-Y90-PRKCQ IGLV(23-?) p-CARMA1 oligomer IGKV2-28 ATPIg heavy chain V-III region DOB PSMB6 Ig lambda chain V-VI region AR MALT1 oligomer IGLC7 Ig heavy chain V-III region BUT H2OBCL10PSMD4 PI(3,4,5)P3IGLV7-46(1-?) IGLV4-3(1-?) IGHV(1-?) Ig kappa chain V-I region AU IGLC2 IGLV3-25(1-?) Ig heavy chain V-III region DOB TRAF6 oligomer IGLV3-22(1-?) IGLV4-69(1-?) HRAS ADPIg heavy chain V-III region JON Ig heavy chain V-II region NEWM PLCG1 GRB2-1:SOS1IGLV2-33(1-?) Ig heavy chain V-III region BRO Ig kappa chain V region EV15 RAC1:GDPp-T185,Y187-MAPK1 Ig lambda chain V-I region NEW Ig heavy chain V-II region MCE Ig heavy chain V-III region TRO DAGs p-10Y-NTAL:p-SHC1:GRB2:SOSITPR2 Ig lambda chain V-IV region Hil IGLV11-55(1-?) IGLV5-37(1-?) Fe3+ PDPK1p-Y223,Y551-BTK p-Y173-VAV3 Ig heavy chain V-II region MCE DAG:p-5Y-PKC-theta:p-S552,S645-CARMA1PI(3,4,5)P3p-Y113,128,145-LCP2 SYK/FYNDAGs DAGs SOS1 PSMB10 Ig kappa chain V-I region AG p-MAP2K4/p-MAP2K7IGLV2-18(1-?) p-Y172-VAV2 Ig heavy chain V-II region OU p-Y90,T219,T538,S676,S695-PRKCQ SOS1 FBXW11 IGLV3-22(1-?) UBE2V1 Ig lambda chain V-II region NEI FCER1A GRB2-1 PLCG2 PI(3,4,5)P3 p-10Y-LAT2 AMPITK PI(3,4,5)P3 Ub-200-UBB(153-228) p-5Y-LAT-2 VAV2 Ig heavy chain V-II region MCE K63polyUb-TRAF6 IGHV(1-?) p-Y239,Y240,Y317-SHC1-2 PiIGKV4-1(21-?) Ig lambda chain V-I region NEW PRKQC closedconformationIGLV4-60(1-?) IGLV3-25(1-?) PPP3R1 Ig lambda chain V-IV region Hil ATPCa2+ SCF-beta-TRCPVAV1 p-SHC1:GRB2:SOSIGLV2-18(1-?) p-Y113,128,145-LCP2 p-Y239,Y240,Y317-SHC1-2 PLCG1 p-MAPK8/9/10ITPR2 p-4Y-PLCG2 ATPFCERI:IgEIg kappa chain V-III region POM GRAP2 Ig heavy chain V-III region DOB PLCG1 Ig heavy chain V-III region BUT MALT1 PDPK1 IGKV2D-30 p-Y113,128,145-LCP2 PSMB3 p-Y173-VAV3 26S proteasomePDPK1 p-T221,Y223-MAPK10 Ig kappa chain V-I region AU IGLC6 PSME1 PIP3, PI(3,4)P2Ig lambda chain V-IV region Bau FCER1G ADPPSMD14 p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAVp-5Y-LAT-2 Ig heavy chain V-II region NEWM IGKVA18(21-?) p-5Y-LAT-2 MyrG-p-Y420-FYN VAV2 IGLV4-60(1-?) Ig heavy chain V-III region JON MAP2K7Ig heavy chain V-II region ARH-77 RasGRPs:DAG:Ca2+IGLV3-16(1-?) VAV1 PLCG2 LAT-2VAV3 Ig heavy chain V-I region HG3 MALT1 oligomer DAG:p-5Y-PKC-theta:CBM complexPSMD12 MS4A2 Ig kappa chain V-I region Daudi Ig lambda chain V-III region LOI PI(3,4,5)P3 GRAP2 TEC,BTK,ITK,(TXK)IGLV7-43(1-?) p-S271,T275-MAP2K7p-Y90,T219,T538,S676,S695-PRKCQ Ig kappa chain V-III region VG p-5Y-LAT-2 DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6ATPIg kappa chain V-I region Daudi Ig heavy chain V-III region TRO LAT2MALT1 oligomer IGLC2 IGKC SOS1 GRB2-1 IGLV1-36(1-?) Ig kappa chain V-I region Wes IGLV7-46(1-?) IGLV8-61(1-?) K63polyUbRASGRP4 Ig kappa chain V-I region DEE IGLC2 p-S265-NFATC3 IGLC7 PAK1 PSMA8 Ub-48-RPS27A(1-76) K63polyUb-TRAF6 p-Y206,Y519-TEC Ig lambda chain V-I region NEWM Ig heavy chain V-I region HG3 Allergin Ig heavy chain V-III region WEA Ig heavy chain V-III region KOL IGLV2-33(1-?) PPP3R1 ATPPSMA4 PI(3,4)P2 Ig kappa chain V-I region Gal ATPGRB2-1 PSMC3 Ig lambda chain V-IV region Kern ADPp-2S-cJUN:p-2S,2T-cFOSUb-TRAF6 trimerbound to CBMcomplexNF-kB complexp-S243-NFATC2 DAGs Ig lambda chain V-I region NEW p-S177,S181-IKKB:IKKA:pUb-NEMOp-6Y-SYK Ig lambda chain V-II region TOG p-Y420-TXK ADPIGKVA18(21-?) IGLV4-60(1-?) CALM1 IGHV1-2 p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCGIGLV5-45(1-?) VAV1 ATPp-5Y-LAT-2 IGLV1-40(1-?) RAC1 Ca2+ Ig kappa chain V-I region HK101 p-13S-NFATC3 Zn2+ TAB1 Ig kappa chain V-II region Cum Ig heavy chain V-III region BUT TAB3 IGLV4-69(1-?) RELA IGLV3-12(1-?) PSMD13 Ig kappa chain V region EV15 BCL10 oligomer p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3PLCG2 Ig lambda chain V-I region HA IGKV3D-20 p-Y1400,Y1412-MAP3K1Ig heavy chain V-III region WEA KRAS Ig kappa chain V-I region Gal Ig lambda chain V-I region NEW IGLV8-61(1-?) Ig lambda chain V region 4A CARD11GRAP2 Ca2+UBE2D2,UBE2D1,(CDC34)Ca2+Ig kappa chain V-I region DEE Ub-48-UBB(1-76) IGLV3-25(1-?) Ig heavy chain V-III region JON Ig lambda chain V-IV region Bau p-Y90,T219,T538,S676,S695-PRKCQ IGLV11-55(1-?) SHFM1 UBE2V1 Calcineurin:Calmodulin (CaN:CaM)IGLV7-43(1-?) PDK1:PIP2,PIP3Ig heavy chain V-I region EU IGKC p-5Y-LAT:p-SHC1:GRB2:SOS1IGLV3-12(1-?) Ig lambda chain V-I region VOR UBE2D2 VAV3 p-Y396-LYN IGHV(1-?) PSMB1 IGLC7 IGLV3-22(1-?) IGLV2-18(1-?) SOS1 Ig heavy chain V-III region CAM p-S265-NFATC3 IGLV5-37(1-?) CALM1 ATPIg lambda chain V-II region MGC Ig heavy chain V-I region EU Ig kappa chain V-I region DEE IGLV2-23(1-?) Ig heavy chain V-II region ARH-77 IGLV5-45(1-?) Ig kappa chain V-I region Daudi DAGs p-5Y-LAT-2 p-CARMA1 oligomer IGLC3 IGLV3-22(1-?) p-T,Y MAPK dimersPSMC4 PSMD5 Ig kappa chain V-I region HK101 IGKV1-5(23-?) p-Y180,Y512-ITK Ig lambda chain V-II region MGC Ig heavy chain V-III region CAM IGHV(1-?) Allergin p-Y90,T219,T538,S676,S695-PRKCQ p-Y174-VAV1 p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTPIg heavy chain V-II region MCE PI(3,4,5)P3 Ig kappa chain V-I region HK101 TAB1:TAB2,TAB3:TAK1p-4Y-PLCG1 Ig lambda chain V-II region BOH IGLC1 PSMA7 ADPIGHE Ig lambda chain V-VI region AR p-Y90,T219,T538,S676,S695-PRKCQ PKC-theta (open):DAGIGLV2-11(1-?) IGLV7-43(1-?) ATPZn2+ p-5Y-LAT-2 LCP2 PSMB5 IGKC PIK3CA FOSSOS1 GRAP2 K63polyUb-TRAF6 Ig kappa chain V-III region POM NFKB1(1-433) IGLV10-54(1-?) DAGs Ig lambda chain V-I region NEWM ITK NFKB1(1-433) PAK dimerp-5Y-LAT-2 IGLC1 p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3MALT1 p-Y113,128,145-LCP2 IGKVA18(21-?) PI(3,4,5)P3MAP3K1NF-kB complexIg kappa chain V-I region BAN BCL10 oligomer PLCG1 IGLV1-44(1-?) Ig kappa chain V region EV15 Ig lambda chain V-IV region Kern p-BCL10 PI(3,4,5)P3 NFKB1(1-433) IGKV3D-20 ADPADPIg heavy chain V-III region CAM PIK3R2 p-Y396-LYN IGLC7 IGHV7-81(1-?) PI(3,4,5)P3 IGKV2D-30 CALM1IGLV10-54(1-?) Ig heavy chain V-II region NEWM ADPp-Y396-LYN PPP3CA Ub-276-UBC(229-304) p-Y239,Y240,Y317-SHC1-2 Ig heavy chain V-II region ARH-77 p-Y239,Y240,Y317-SHC1-2 IGLV1-44(1-?) p-Y239,Y240,Y317-SHC1-2 p-Y519-TEC IGLC1 GRAP2 p-CARMA1 oligomer Ig kappa chain V-I region Wes PLCG1 IkB(alpha):NF-kBcomplexIg kappa chain V-III region VG PSME2 GRB2-1 Ig lambda chain V-III region SH IGLV2-23(1-?) Ig lambda chain V-I region VOR p-Y239,Y240,Y317-SHC1-2 p-Y551-BTK IgH heavy chain V-III region VH26 precursor IGLV10-54(1-?) SOS1 IGLV4-60(1-?) Ig lambda chain V-III region SH IGLV2-23(1-?) MALT1 oligomer p-S141,T402-PAK2 Ig heavy chain V-III region DOB IGHV1-2 PIP3 activates AKTsignalingPLCG1 ADPMALT1 LCP2 IGLV4-60(1-?) PSMA3 Ig heavy chain V-II region WAH IGLC1 SHC1-2p-S177,S181-IKKB:IKKA:NEMOSOS1 Ig kappa chain V-II region Cum p-5Y-LAT-2 IGKV4-1(21-?) Ig lambda chain V-I region NEWM p-Y239,Y240,Y317-SHC1-2p-S144,T423-PAK1 SOS1 ATPNFAT:CaN:CaMp-S257-NFATC1 GRB2-1 RELA ITPR2 Ig heavy chain V-III region JON p-10Y-LAT2 PI(4,5)P2NFAT:CaN:CaMGRB2-1 Ig kappa chain V-III region VG Ig kappa chain V-I region BAN p21 RAS:GDPIg heavy chain V-I region HG3 VAV1 RAC1 IGKV1-5(23-?) IGLV7-43(1-?) CHUK Ig lambda chain V-II region MGC IGKV1-5(23-?) GTP BTK VAV3 DAGsRAF/MAP kinasecascadep-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAVIg kappa chain V-I region BAN TAB2 PI(3,4)P2 UBE2N ATPp-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimerAHCYL1 VAV2 p-5Y-LAT-2 p-14S-NFATC2 Ig lambda chain V-IV region Kern LCP2 p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3KIg heavy chain V-III region TRO p-Y90-PKC-theta:DAGUb-48-UBC(1-76) PSMB11 IGKV3D-20 IGLV1-44(1-?) PI(3,4,5)P3 Ig kappa chain V-II region Cum p-FCERI aggregate ATPp-5Y-LAT-2 PIK3CB ATPIGKV1-12 p-5Y-LAT-2ATPp-Y90,T219,T538,S676,S695-PRKCQ PPP3R1 Ig lambda chain V-II region TOG RASGRP4 p-Y512-ITK MAP3K7 IGLC7 IGLC3 Ub-124-UBB(77-152) ADPVAV3 CDC34 IGLV7-46(1-?) PLC gamma1,2IGLV1-40(1-?) Ig kappa chain V-I region AU VAV1 p-S257,T261-MAP2K4ADPIKBKB Ig lambda chain V-II region NEI IGLV8-61(1-?) Ig kappa chain V-III region POM DAGs Ig kappa chain V-I region Gal PPP3CA Ub-200-UBC(153-228) ADPIg kappa chain V-III region B6 Ig heavy chain V-III region KOL PI(3,4,5)P3 MALT1 oligomer p-Y113,128,145-LCP2 IGLV3-16(1-?) p-Y113,128,145-LCP2 IGKVA18(21-?) ATPIg heavy chain V-III region CAM IGLV3-16(1-?) Ig lambda chain V-II region MGC IGLV7-46(1-?) TEC Ig lambda chain V-III region LOI Ig heavy chain V-I region EU DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6PIK3R1 GRB2-1 RAC1 K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complexPSMA6 PI(3,4,5)P3Ig lambda chain V-II region BOH Allergin Ig heavy chain V-I region HG3 Ig lambda chain V-I region VOR IGLV1-36(1-?) TRAF6Ca2+ PLCG2 IGLV4-69(1-?) Ig kappa chain V-I region BAN GRB2-1 IGLV1-44(1-?) IGLV3-12(1-?) Fe3+ PSMC2 p-S32,36-IkB-alpha:NF-kB complexIg heavy chain V-II region OU TAB2 Ig kappa chain V-II region RPMI 6410 ADPp-T183,Y185-MAPK9 MAP2K4VAV1,2,3IGLV3-16(1-?) PAK1 GRAP2 IGLV3-27(1-?) DAGs GTP ADPADPIg heavy chain V-III region BRO Ig lambda chain V-II region TOG Allergin K48PolyUb-K21,22-p-S32,S36-IkBA p-T,Y-MAPK8 Ig heavy chain V-III region TRO PSMD11 IGLC6 Ig heavy chain V-III region BUT Ig lambda chain V-VI region AR Ig lambda chain V-I region VOR PSMD8 p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2IGKV1-12 Ig kappa chain V-III region B6 SOS1 MAPK8/9/10IGHV(1-?) NFKBIA IGLC3 Fe3+ IgH heavy chain V-III region VH26 precursor p-Y113,128,145-LCP2 p-Y420-TXK p-5Y-PKC-theta:DAGMAPK10 DAGs IGLV4-3(1-?) Ig kappa chain V-II region FR IGLV4-3(1-?) IGLV4-69(1-?) GRB2-1 Ig heavy chain V-II region ARH-77 Ig lambda chain V-II region NEI Ig kappa chain V-I region AU IgH heavy chain V-III region VH26 precursor PSMA1 IGLV11-55(1-?) PRKCQ Ig kappa chain V-I region Wes p-6Y-SYK IGLC6 PSMB9 UBE2N PSMD1 p-Y452,Y476,Y584-GAB2 PLCG2 PSMD2 Ig lambda chain V-IV region Bau Ig lambda chain V-IV region Hil Ig kappa chain V-III region POM Ig heavy chain V-III region JON Zn2+ p-10Y-LAT2 ADPIGKV1-12 IGLV1-40(1-?) p-Y519-TEC Ig heavy chain V-III region BUT p-S177,S181-IKBKB Ig heavy chain V-I region EU IGHV1-2 PSMC1 IGKV3D-20 IGLV2-33(1-?) GRB2-1 IKBKG DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3IGLV5-45(1-?) Ig kappa chain V-I region Gal IGKV2D-30 Ig kappa chain V-I region BAN VAV3 p-FCERI aggregate ADPIGLV2-11(1-?) GRB2-1 Ig kappa chain V-III region B6 LYNIGKV1-12 Ig heavy chain V-II region NEWM p-Y396-LYN GRB2-1 IGKVA18(21-?) MALT1 oligomer p-Y239,Y240,Y317-SHC1-2 Ig lambda chain V-I region HA IGLV8-61(1-?) Ub-504-UBC(457-532) KRAS Ig kappa chain V-II region RPMI 6410 p-10Y-NTAL:p-SHC1:GRB2:SOS:GAB2Ig kappa chain V-II region Cum UBE2D1 p-10Y-LAT2IGLV3-25(1-?) RELA Ig lambda chain V-II region TOG PIK3R1 IP3 receptorhomotetramerATPIg kappa chain V-I region AG DAGs IGKV3D-20 IGLV2-11(1-?) Ig lambda chain V-III region LOI IGLV1-40(1-?) IGLV3-16(1-?) TXK PSMA5 RASGRP2 Ig heavy chain V-III region JON RASGRP2 SOS1 SOS1 VAV2 Ig lambda chain V-II region NEI PLCG1 IGLV5-37(1-?) Ig heavy chain V-II region MCE IGLV11-55(1-?) p-Y90,T219,T538,S676,S695-PRKCQ p-T202,Y204-MAPK3 PPP3R1 PSME3 K63polyUb-NEMO PLCG2 PSMB7 IGHE p-S257-NFATC1 Ub-124-UBC(77-152) p-6Y-SYK Ig heavy chain V-III region WEA p-CARMA1 oligomer IGLV2-23(1-?) VAV1 p-Y239,Y240,Y317-SHC1-2 IGLV1-36(1-?) IGKV1-5(23-?) IGLV5-37(1-?) p-Y239,Y240,Y317-SHC1-2 Ig kappa chain V-III region B6 ITPR3 PLCG2 IGHE Ig lambda chain V-VI region AR AHCYL1:NAD+:ITPR1:I(1,4,5)P3 tetramerATPIGHE SOS1 VAV3 p-Y174-VAV1 I(1,4,5)P3 IGLV(23-?) SOS1 ATPCalcineurin (CaN)PI(3,4)P2 Ig lambda chain V-IV region Bau IGLV5-45(1-?) NFKB1(1-433) Ig lambda chain V-I region NEW p21 RAS:GTPIg kappa chain V region EV15 GADS:SLP76NFKB1(1-433) Ig kappa chain V-I region HK101 p-Y239,Y240,Y317-SHC1-2 Ig lambda chain V-II region TOG PI(3,4,5)P3 Ig heavy chain V-II region NEWM Ig heavy chain V-III region KOL ATPIg kappa chain V-I region DEE K48-UbIg heavy chain V-II region WAH Ig heavy chain V-III region KOL SOS1 Ig heavy chain V-III region TRO IGLV5-45(1-?) IGLV11-55(1-?) IGLV7-46(1-?) GDPIGLV1-36(1-?) Ig heavy chain V-II region WAH Ig heavy chain V-III region BRO p-5Y-LAT-2 IGHV1-2 VAV1 IGKV2-28 IGLV(23-?) BCL10 oligomer Ca2+IGLC6 GDP Ig kappa chain V region EV15 GAB2Ig kappa chain V-I region Wes PSMD10 PIK3CB PAK2 PLCG2 Ig lambda chain V region 4A Ig lambda chain V-IV region Hil CHUK:IKBKB:IKBKGIGKV4-1(21-?) CUL1 p-2Y-PAKIg heavy chain V-II region ARH-77 GRAP2 p-Y90,T219,T538,S676,S695-PRKCQ Ig lambda chain V-II region NEI PSMF1 IGLV3-12(1-?) RasGRPsIg heavy chain V-III region WEA Ig lambda chain V-IV region Bau IGKV2-28 p-Y90,T219,T538,S676,S695-PRKCQ Ub-352-UBC(305-380) GRB2-1 TAB3 PSMD7 IGKV2-28 Ub-48-UBA52(1-76) Ig lambda chain V-III region SH IGLV5-37(1-?) IGHV7-81(1-?) CALM1 p-Y239,Y240,Y317-SHC1-2 Ig heavy chain V-III region BRO BCL10:MALT1IGLV10-54(1-?) p-S63,S73-JUNIg heavy chain V-I region EU IGLV3-27(1-?) NRAS p-CARMA1 oligomer PSMC5 IGLV1-44(1-?) Ig kappa chain V-I region AG IGLV7-46(1-?) TEC IGLV1-36(1-?) p-Y180,Y512-ITK VAV2 Ig heavy chain V-II region WAH IGLV4-3(1-?) PLCG2 ITPR1 IGLV2-33(1-?) IGKV2D-30 Ig heavy chain V-III region KOL Ig kappa chain V-I region Gal p-Y452,Y476,Y584-GAB2 GRB2-1 IGLV3-25(1-?) SOS1 IGLC6 DAG:p-5Y-PKC-theta:CBM oligomerBCL10 oligomer IgH heavy chain V-III region VH26 precursor PAK2 IGKVA18(21-?) IGLV2-33(1-?) VAV2 PPP3CA PPP3CB Ig heavy chain V-II region MCE p-T183,Y185-MAPK9 Ig lambda chain V-I region NEWM CALM1:4xCa2+Ig kappa chain V-II region FR IGLC6 Ig kappa chain V-I region AG PIK3R2 PI(4,5)P2RASGRP1 Ig lambda chain V-IV region Kern p-T221,Y223-MAPK10 IGLV1-40(1-?) IGLC2 p-5Y-LAT-2 ADPTXK TAB2 p-T,Y-MAPK8 BCL10 IGLV1-36(1-?) p-FCERI aggregate ATPIGLV2-23(1-?) p-Y551-BTK Ig kappa chain V-II region FR PSMD6 IGLV(23-?) Ig lambda chain V region 4A Ig lambda chain V-II region BOH Ig lambda chain V-I region HA p-Y512-ITK Ig kappa chain V-I region Daudi IGHV7-81(1-?) IGLV1-40(1-?) IGLV4-69(1-?) PPP3CB Ig kappa chain V-I region AU GTPp-Y113,128,145-LCP2 IGLV3-27(1-?) p-Y113,128,145-LCP2 TRAF6 PSMB4 IGLV7-43(1-?) GRAP2 ATPIGHV(1-?) Ig lambda chain V-I region HA PI(3,4,5)P3 IGLV2-18(1-?) p-Y396-LYN GDPITPR1 p-S243-NFATC2 ATPPIK3CA Ig lambda chain V-IV region Bau DAGs Ig lambda chain V-II region MGC SYKIGKV1-12 Ig kappa chain V-I region Gal p-Y239,Y240,Y317-SHC1-2 SOS1 p-SYK/p-BTKIGKV2D-30 IGLV11-55(1-?) BCL10 BTK p-Y239,Y240,Y317-SHC1-2 Ub-580-UBC(533-608) PSMB2 ITPR1 p-Y174-VAV1 IGLV2-11(1-?) GRAP2 Ig lambda chain V-IV region Hil