Glycerophospholipid biosynthesis (Homo sapiens)

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76, 83, 110, 119, 124...16720133, 43, 75, 90, 16810, 29, 6022, 128, 16374105, 2024420628, 65, 79, 139, 193113, 140, 19816, 17324, 133, 1699, 1248, 95, 19010, 29, 60118, 14911, 54, 10753, 88, 18037, 6640, 67, 166, 17051, 127, 1541831285, 69, 1281288, 46, 57, 9150, 121, 123, 14541, 4992, 94, 15681, 11127, 32, 99, 18713328, 34, 62, 146, 175...17, 78, 84, 102, 19920612821, 68, 121, 143, 2005, 22, 69, 81, 128135, 17236, 63, 1771, 7, 13, 18, 71...65, 80, 89, 95, 114...12845, 15223, 12018828, 62, 14639, 87, 144, 155, 15728, 65, 79, 139, 19335, 17674, 134, 1826012828, 34, 42, 65, 79...122, 131, 141, 186138, 198966052, 15374, 128108, 148, 159412864, 83, 86, 109, 118...18425, 5631, 3874, 128125, 1625, 22, 69, 117, 128...92, 94, 1565, 13, 69, 74, 82...105, 2021, 7, 13, 18, 71...1, 7, 13, 18, 71...1, 7, 13, 18, 71...117, 151, 20392, 94, 15623, 120, 171142, 16070, 192161137, 15024, 133, 16928, 34, 62, 146, 175...12028, 34, 42, 65, 79...28, 62, 146743818420, 104, 174, 1815, 22, 69, 81, 1285, 69, 1287493, 116, 1299720619, 97, 136, 19492, 94, 1561, 7, 13, 18, 71...5, 6, 15, 22, 69...106, 146165, 2055, 69128111, 16117, 78, 84, 199128, 16314, 1611, 7, 13, 18, 71...12847, 731919, 12, 30, 59, 72...5, 69118, 1492, 555, 69, 12896106, 14658, 13714, 161, 1679, 12326, 112, 17861, 130, 20712817, 78, 84, 1999, 12, 30, 59, 72...48, 80, 955, 69, 128peroxisomal matrixmitochondrial intermembrane spaceendoplasmic reticulum lumencytosolmitochondrial matrixGolgi lumenmitochondrial intermembrane spacelate endosome lumenmitochondrial matrixPLA2G4F LCFA(-)PCYT2 dimerETNPPL PLA2G5 CTPHADHA Mg2+ PGH2OPLA2G4E CDP-ETAPS2-acyl LPSPLA2G4A LPCAT4 Mn2+ ETNK2 PCOSBPL8 PLA2G2F Ca2+ 1-acyl LPEPLA2G4A 1-acyl LPI2-acyl LPEPLA2G4A LCFA(-)acyl-CoAOSBPL5 AdoMetPLA2(6)PLA2G10 CHKA PHOSPHO1:Mg2+Ca2+ PLA2(8)PI GPCPD1PLA2G4D PLA2G2F NAPEAGPAT9 LPGATPIDLCLCoA-SHLCFA(-)Ca2+ PITPNM1,2,3PGSTARD7 PITPNM3 LPCAT3 PLA2G4A PLA2G4F CoA-SHacyl-CoAPLA2G4CPCTP LCFA(-)CMPPLA2G1B PLA2G15PI acyl-CoAMn2+ PLA2G1B H2OChoLCFA(-)PGH2OGPAM/GPAT2LCLAT1 PLA2G4CPI4Pacyl-CoALCFA(-)PLD6 PLA2G4CPLA2G2A:Ca2+Mg2+ CoA-SHCa2+ PLA2G16 LPCAT1 Casein kinase IICDIPT:Mg2+/Mn2+GO3P1-acyl LPSCoA-SHAWAT21-acyl LPAGNPAT2-acyl LPADGAT1 PAGPAEAPLA2G4D PETAPLA2G2A NADHLPEATLPA,PAPGPH2OPLA2G2A PNPLA3 PCYT1 dimerCa2+ PLA2G1B PLD1 LCFA(-)CHKA PLA2G10 ACP6MLCLGPAM(1-828) LPGAT1 PCPLA2G2E LIPH, IPLA2G4F PISD(378-409) CH3CHOPA PLA2G3 PLA2G4CAGPATH+PLB1PTDSS1PLA2G4A PLA2G6 ABHD4H2Oacyl-CoACPNEsLCLAT1PLA2(3)PTPMT1PLBD1 DDHD2 PGS1L-SerPC CoA-SHlysoPCMAG,DAGTMEM86BLPGAT1 PLA2(15)PPiCoA-SH1-acyl LPGPLA2G4D PLA2G2A:Ca2+Ac-CoAPLD4 STARD7PLA2(1)ETAGPETAM Mn2+ PLA2G2D OSBPL10 STARD10H2OCa2+ CoA-SHacyl-CoAPLA2G2A LPSATPITPNB PLA2G4E PLA2G4F MLCLcardiolipinGPAT2 DAGLPIN1 CMPCa2+ CLPLA2G4B 1-acyl LPSPLA2(15)DHAPLCFA(-)CSNK2A2 H2OPLA2G4F MBOAT2 LPCAT1AGPCETAH2OCHPT1 PLA2(16)PLA2G4C PLA2G4A H2ODAG PLA2(16)H2OLIPI CPNEs:PLcardiolipinPCYT1B PLA2G4D PLA2G5 PITPNB CSNK2B H2OATPPETAL-SerPCYT1A ChoTAZPLA2G12A PCTPH2OLCFA(-)H2OPC AGK:Mg2+PIPLA2G2A LPCAT4 ALPI PLA2G4B PLA2G2F STARD10 CoA-SHPLA2G4D SLC44A5 H2OLPCATPLA2(1)H2OPLA1AMFSD2ALPCAT4 PLBD1 PLA2G4D PLA2(13)PTDSS2CPNE1 ChoMg2+ G3PZn2+ acyl-CoAGPCHO RARRES3 AGPAT2 ADPAdoHcyCoA-SHOSBPL5,8,10PPiPLA2G4E PLD2 PAMBOAT1 HADHB PLA2G12A PLA2G4A PC LCFA(-)PITPNM2 PSPLA2G2A H2OCPNE3 Mg2+ AGPAT3 LPCAT1 PLA2G4D BMPAGPAT5 CEPT1:Mg2+/Mn2+H2OPLA2G6PiPLA2G4A:Ca2+GPChoCO2H2OLPCAT3 CTPLPCAT4 ADPPLA2(4)FADH2fatty aldehydeETAPLA2G4B H2OPLA2G4F PLA2(14)PLA2G4A LCFA(-)ATPAlcoholPHOSPHO1 PLBD1 PLA2G4D PiLPSATATPacyl-CoAMg2+ Ca2+ DLCLPLA2(10)PG1-acyl LPALPCAT3 CPNE3 CHK dimerGlycerolPLD1-4/6acyl-CoAH2OHRASLS CMPPE2-acyl LPICPNE7 PITPNM1 PChoLPCAT3 Ca2+ GPChoLPCAT3 EPT1 Ca2+ Mg2+ AGPAT6 1-acyl LPIMg2+ PLA2G4D MBOAT1 PLA2G4B PLA2G4B CPNE6 PITPNB AcChoPLA2G4A PLA2(2)Pyruvoyl MBOAT2 PNPLA2 Ca2+ CoA-SHPCp-S284-STARD10LPCAT1 HRASLS2 CPNE7 ETNPPL tetramerLPCAT1PLA2G4BCa2+ PLBD1 PLD3 PLA2G4A H2OCDIPT PPiPLA2G4D PLA2(9)DGAT2L6 LPCAT2 LPCAT4 H2OLCFA(-)H2OLCFA(-)G3PMYS-LPAPC 1-acyl LPCPNPLA8 1-acyl LPGDGAT2L7P CoA-SHLPCAT1 SLC44A3 ALPI:2Ca2+:Mg2+dimerSTARD10:LPCAT1:PCMBOAT2 PMCHO MBOAT2 LPINphosphate monoesterAcChoPLA2G6 PLA2G2A:Ca2+LPC(14:0)CDP-DAGDGAT1/2GPCHO, GPETAMAGPAT4 STARD10:PCNAD+LCFA(-)CoA-SHLCFA(-)PLA2G4F LCFA(-)MGLL dimerH2OCHKB PLA2G16 MBOAT7LIPH PCTP:PCLPCAT4 AGPAT1 PLA2G2F LPC (22:6)PLA2(5)H2Oacyl-CoAacyl-CoA2-acyl LPGPLA2G2E FADPLA2G2F Ca2+ PLA2G4A LCFA(-)PLA2G2A acyl-CoACMPPLA2G4B PGDAGPLA2(11)PLD1 PC LPIN2 H2OSLC44A2 Pi1-MMGPIGlycerolHADH octamerPCYT2 PGPLA2G16 DGAT2L6,L7PCa2+PLA2G10 Acyl-CoAacyl-CoA1-acyl LPE1-acyl LPCLPCAT1 PLA2G4B H2OSLC44A1 PLD2 DGAT2 2-MAGfatty acidH2OTAGPC:PITPNBPCPLA2(12)PL CHKB 2-acyl LPCCa2+ 1-acyl LPCPLA2G4C PSLCFA(-)PEPLA2G2F PLA2G4B PLD1/2H2OPLD6 dimerPLA2G2E GlycerolCDS1 PLA2G2A PMETAM CSNK2A1 PLA2(7)PLA2G4B 2-acyl LPGMg2+ ETNK1 Na+Ca2+ GPD1L STARD7 GPD1/GPD1L homodimerLPCAT3 CDP-DAGPLA2G4F PEDDHD1,2H2OCPNE6 LPCAT2 PLA2G4D LysoPtdChoCEPT1 LCFA(-)LPC (22:6)Ca2+ 1-acyl LPECa2+ Mn2+ H2OCa2+ DAGCholinesterasePEMTCa2+ PLPLA2G4CPLA2G10 ChoPLA2(1)GlycerolBCHE PLA2G16 PLA2G4D PLA2G4A PNPLA2/3CRLS1H2OCHATPLD6 ADPCoA-SHAGK MBOAT7acyl-CoAPLA2G1B MGLL LPIN3 Na+PISD(1-377) MIGA1 Ca2+ PLA2G4D PLA2G4E 1-acyl LPGMIGA complexesInsCoA-SHPLA2G5 PLA2G4F Ca2+ H2OPADDHD1 PLA2G2D PLA2G2E PLA2G4D PLA2G4E ADPAGPAT6PLBD1 PI4PSTARD7:PCG3PHRASLS5 PLA2G12A PLA2G4E PLA2G2F PMCHO, PMETAMPLA2G2D Ca2+ PIMAG AGPAT5PLA2G4D PLA2G2A acetatePITPNB ChoPGPiCTL1-5PLA2G2D CTPPLA2G12A STARD10 acyl-CoALCFA(-)PLA2G2A ABHD3GPD2Ca2+ PLA2G4B MAGH2OSTARD7:PCLPCAT4 CEPT1/EPT1H2OLPEATCDP-ChoPC 2-acyl LPSacyl groupMBOAT1 MIGA2 PLA2G4F LPGATHRASLSCMPRCOOHPLA2G2A PiLPCAT4 CMPacyl-CoAPEPCPISD:PyruvoylLPCAT1 CDS2ChoPISLC44A4 H2OCoA-SHPLA2G16 PAG3PPECHPT1:Mg2+/Mn2+CHK/ETNKCPNE1 PC PLA2R1(21-?)H2OPLA2G5 ATPCDS1:Mg2+PSPLA2GNH3CoA-SHPC1-acyl LPAPC:PITPNBGPETALCFA(-)PLA2G4F PLA2G4E Ca2+ PLA2G3 LPA PI:PITPNBCRLS1LPCAT4 PPiPI:PITPNBMBOAT1 ACHE CEPT1 PNPLA8 PLA2(8)GPD1 PLA2G4A 38, 11538