Small Ligand GPCRs (Homo sapiens)

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ProstanoidsCannabinoidMelatoninLysophosphatidicAcidPlatelet ActivatingGPR50EDG5MTNR1APTGER4EDG1TBXA2RCNR2EDG3CNR1EDG2PTGIRPTGER1Gi PathwayEDG6Gq/G11 PathwayMTNR1BPTGER3Gq/G11 PathwayPTGDRPTGFRPTGER2PTAFR


Description

G protein–coupled receptors (GPCRs) which are also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses. Coupling with G proteins, they are called seven-transmembrane receptors because they pass through the cell membrane seven times. Source: Wikipedia These small ligand receptors are part of the Rhodopsin-like family of GPCRs. Source: Wikipedia

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Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
102206view19:59, 10 December 2018EgonwBetter ID for the ligand.
96077view18:44, 15 February 2018KhanspersModified description
96069view18:40, 15 February 2018KhanspersModified description
74422view13:17, 18 April 2014EgonwAdded missing interactions.
74421view13:15, 18 April 2014EgonwConverted four labels into metabolite DataNodes with an identifier.
68971view17:41, 8 July 2013MaintBotUpdated to 2013 gpml schema
59180view18:44, 22 February 2013MaintBotUpdated Ensembl and UniProt data source
45150view01:23, 7 October 2011AlexanderPicoSpecify description
45149view01:23, 7 October 2011AlexanderPicofixed db refs
45124view00:11, 7 October 2011KhanspersOntology Term : 'G protein mediated signaling pathway' added !
41142view23:39, 1 March 2011MaintBotRemoved redundant pathway information and comments
38850view17:54, 24 September 2010KhanspersAdded pathway links
38849view17:52, 24 September 2010Khanspers
34495view22:28, 16 December 2009KhanspersAdded connector
32376view16:52, 15 August 2009MaintBotFixed text labels
32012view13:20, 14 August 2009MaintBotFixed group labels
21199view11:31, 14 November 2008MaintBot[[Pathway:Homo sapiens:Small ligand GPCRs]] moved to [[Pathway:WP247]]: Moved to stable identifier
14444view22:48, 22 May 2008AlexanderPicoReorganized for clarity
14441view22:43, 22 May 2008AlexanderPicoConnected!
14436view22:41, 22 May 2008AlexanderPicoPeriodical save, work in progress
14431view22:32, 22 May 2008AlexanderPicoFixed labels
14429view22:32, 22 May 2008AlexanderPicoGrouped by class
13014view11:06, 17 May 2008MaintBotSticky edges patch by Sjoerd
8390view13:46, 7 January 2008MaintBot[[Pathway:Human:Small ligand GPCRs]] moved to [[Pathway:Homo sapiens:Small ligand GPCRs]]: Renaming species
7812view16:19, 18 December 2007MaintBotfixed category names
7446view12:42, 4 November 2007MaintBotAdded categories to GPML
6390view22:18, 22 May 2007Nsalomonisgpml file for [[Human:Small_ligand_GPCRs]]

External references

DataNodes

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NameTypeDatabase referenceComment
CNR1GeneProduct1268 (Entrez Gene)
CNR2GeneProduct1269 (Entrez Gene)
CannabinoidMetaboliteCHEBI:67194 (ChEBI)
EDG1GeneProduct1901 (Entrez Gene)
EDG2GeneProduct1902 (Entrez Gene)
EDG3GeneProduct1903 (Entrez Gene)
EDG5GeneProduct9294 (Entrez Gene)
EDG6GeneProduct8698 (Entrez Gene)
GPR50GeneProductENSG00000102195 (Ensembl)
Gi PathwayPathwayWP35 (WikiPathways)
Gq/G11 PathwayPathwayWP35 (WikiPathways)
Lysophosphatidic AcidMetaboliteCHEBI:32957 (ChEBI)
MTNR1AGeneProduct4543 (Entrez Gene)
MTNR1BGeneProduct4544 (Entrez Gene)
MelatoninMetaboliteCHEBI:16796 (ChEBI)
PTAFRGeneProduct5724 (Entrez Gene)
PTGDRGeneProduct5729 (Entrez Gene)
PTGER1GeneProduct5731 (Entrez Gene)
PTGER2GeneProduct5732 (Entrez Gene)
PTGER3GeneProduct5733 (Entrez Gene)
PTGER4GeneProduct5734 (Entrez Gene)
PTGFRGeneProduct5737 (Entrez Gene)
PTGIRGeneProduct5739 (Entrez Gene)
ProstanoidsMetaboliteCHEBI:26347 (ChEBI)
TBXA2RGeneProduct6915 (Entrez Gene)

Annotated Interactions

No annotated interactions

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