RalA downstream regulated genes (Homo sapiens)

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1RASNRASRAC2RALBP1SEC5CDC42RAC3HRASEXOC84KRASRAC1ZONABRalA


Description

Downstream genes of RalA signaling pathways, including the Rac-family GTPase-activating protein RLIP (also known as RLIP76 and ralA binding protein 1 (RALBP1)), CDC42(cell division cycle 42), RAC1 (ras-related C3 botulinum toxin substrate 1), RAC2, RAC3, the Y-box transcription factor ZO-1-associated nucleic acidbinding protein (ZONAB, also known as cold shock domain protein A (CSDA)), and two subunits of the exocyst complex, SEC5 (also known as exocyst complex component 2 (EXOC2)) and EXO84 (also known as EXOC8), which are involved in regulating cell proliferation, apoptosis and migration

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Ontology Terms

 

Bibliography

  1. Fei J, Li Y, Zhu X, Luo X; ''miR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia (CML).''; PLoS One, 2012 PubMed

History

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CompareRevisionActionTimeUserComment
79988view18:34, 29 April 2015ZariَAnnotated RAS family gene
69039view17:52, 8 July 2013MaintBotUpdated to 2013 gpml schema
67620view11:34, 26 June 2013DdiglesOntology Term : 'Ras family mediated signaling pathway' added !
53118view01:34, 30 October 2012MaintBotModified categories
51182view21:41, 31 August 2012MaintBotModified description
51121view08:35, 30 August 2012MkutmonOntology Term : 'CML - chronic Myelogenous Leukemia' added !
51120view08:34, 30 August 2012MkutmonModified description
51119view08:26, 30 August 2012MkutmonNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CDC42GeneProduct998 (Entrez Gene)
EXOC84GeneProduct149371 (Entrez Gene)
HRASGeneProduct3265 (Entrez Gene)
KRASGeneProduct3845 (Entrez Gene)
NRASGeneProduct4893 (Entrez Gene)
RAC1GeneProduct5879 (Entrez Gene)
RAC2GeneProduct5880 (Entrez Gene)
RAC3GeneProduct5881 (Entrez Gene)
RALBP1GeneProduct10928 (Entrez Gene)
RalAGeneProduct5898 (Entrez Gene)
SEC5GeneProduct55770 (Entrez Gene)
ZONABGeneProduct8531 (Entrez Gene)

Annotated Interactions

No annotated interactions

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