Cytokines and inflammatory response (Mus musculus)

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1TcEndothelial CellsMHC IIantibodiesClonal expansion of T cellsEosFibroblastsLymphocyte ActivatedKiller Cells (LAK)TCRThNeutrophilThTcHematopoiesisB CellMast CellantigenMacrophageNK cellB CellEosHypothalamus(fever)TcB CellThPlasma CellB CellT-helperT-helperEosHematopoietic Stem CellIl6Il4IfngIl6Il1bIfna1Il4Il2Il7Csf3Il15TnfH2-Eb1Tgfb1Cxcl1Il3TnfIl2IfngIl1bIl2Il4Il1aIl2Il6Il10Il1bIl3Il12bIl10Il15 Inflammatory ResponseTnfCxcl3Il13Cd4PdgfaIl4Il5Il6Il12aIl1aIl3TnfIl11Il10Tgfb1Il5Il13Il6Il2Il3TnfIl10Il15Il2Tgfb1Csf2Il1bIfngIl1aH2-EaIl4Ifnb1Csf2TnfIfna1Csf1Il1aTRBIl12bTcraIl2TnfIl1aIl1b



GenMAPP remarks 
Converted to human by
This pathway was inferred from Homo sapiens pathway WP530(r21794) with a 84% conversion rate.

Quality Tags

Ontology Terms



  1. Kataoka T; ''Chemical biology of inflammatory cytokine signaling.''; J Antibiot (Tokyo), 2009 PubMed Europe PMC Scholia


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116835view10:30, 14 May 2021EweitzModified title
113977view06:46, 14 December 2020EgonwOne more clickable pathway
90712view20:14, 13 December 2016KhanspersModified title
89990view19:08, 6 October 2016Mkutmonfixed unconnected lines
86880view07:47, 14 July 2016MkutmonOntology Term : 'inflammatory response pathway' added !
86879view07:47, 14 July 2016MkutmonOntology Term : 'PW:0000026' removed !
70944view12:14, 17 September 2013YoungwMade box wider
69133view18:15, 8 July 2013MaintBotUpdated to 2013 gpml schema
67129view10:10, 26 June 2013Christine ChichesterOntology Term : 'inflammatory response pathway' added !
53571view10:16, 9 November 2012AndraRDF Tidy adding Entrez Gene identifier
41319view00:24, 2 March 2011MaintBotRemoved redundant pathway information and comments
38654view12:49, 23 September 2010FerryJagersfixed database @ linked pathway
38651view12:40, 23 September 2010FerryJagersLinked Pathway
35248view19:56, 11 February 2010Thomasadded literature
34967view23:51, 8 February 2010KhanspersPeriodical save, work in progress
32844view20:56, 14 September 2009MaintBotAdded xrefs
32363view13:43, 15 August 2009MaintBotFixed text labels
32002view13:17, 14 August 2009MaintBotFixed group labels
31409view20:52, 13 August 2009MaintBotFixed text labels
30837view00:03, 30 July 2009MaintBotConverted from Homo sapiens
21145view11:30, 14 November 2008MaintBot[[Pathway:Mus musculus:Cytokines and Inflammatory Response Biocarta]] moved to [[Pathway:WP222]]: Moved to stable identifier
7980view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Cytokines and Inflammatory Response Biocarta]] moved to [[Pathway:Mus musculus:Cytokines and Inflammatory Response Biocarta]]: Renaming species
7614view16:04, 18 December 2007MaintBotfixed category names
7471view12:42, 4 November 2007MaintBotAdded categories to GPML
6429view22:18, 22 May 2007S.Burelgpml file for [[Mouse:Cytokines_and_Inflammatory_Response_Biocarta]]

External references


View all...
NameTypeDatabase referenceComment
Inflammatory ResponsePathwayWP458 (WikiPathways)
Cd4GeneProduct12504 (Entrez Gene)
Csf1GeneProduct12977 (Entrez Gene)
Csf2GeneProduct12981 (Entrez Gene)
Csf3GeneProduct12985 (Entrez Gene)
Cxcl1GeneProduct14825 (Entrez Gene)
Cxcl3GeneProduct330122 (Entrez Gene)
H2-EaGeneProduct14968 (Entrez Gene)
H2-Eb1GeneProduct14969 (Entrez Gene)
Ifna1GeneProduct15962 (Entrez Gene)
Ifnb1GeneProduct15977 (Entrez Gene)
IfngGeneProduct15978 (Entrez Gene)
Il10GeneProduct16153 (Entrez Gene)
Il11GeneProduct16156 (Entrez Gene)
Il12aGeneProduct16159 (Entrez Gene)
Il12bGeneProduct16160 (Entrez Gene)
Il13GeneProduct16163 (Entrez Gene)
Il15GeneProduct16168 (Entrez Gene)
Il1aGeneProduct16175 (Entrez Gene)
Il1bGeneProduct16176 (Entrez Gene)
Il2GeneProduct16183 (Entrez Gene)
Il3GeneProduct16187 (Entrez Gene)
Il4GeneProduct16189 (Entrez Gene)
Il5GeneProduct16191 (Entrez Gene)
Il6GeneProduct16193 (Entrez Gene)
Il7GeneProduct16196 (Entrez Gene)
PdgfaGeneProduct18590 (Entrez Gene)
TRBGeneProduct6957 (Entrez Gene)
TcraGeneProductMGI:98553 (MGI)
Tgfb1GeneProduct21803 (Entrez Gene)
TnfGeneProduct21926 (Entrez Gene)

Annotated Interactions

No annotated interactions
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