Metabolism of water-soluble vitamins and cofactors (Homo sapiens)

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25, 32, 42, 1007439, 10414, 2425, 42, 10026, 11711312715, 991, 11, 23, 48, 81...226354, 58, 72, 73, 10396941, 47, 8334, 59, 68, 7827, 3826, 65, 11715, 992212564, 77, 124358341, 47, 8386, 10339, 10412674, 10761, 112, 1295, 2044, 8219, 74, 87606918, 552, 53, 70, 114, 13161, 112, 12931, 37, 109, 1159316, 65, 66, 9559, 68, 7831, 37, 109, 11532, 62851133351, 6711310, 16, 65, 66, 76...13229, 40, 75, 101, 110...844, 12352, 5571, 10896, 10217, 36, 90, 978045, 11131, 37, 43, 79, 109...1308, 50, 12013828931, 37, 43, 79, 109...57, 13311630, 446, 8, 12, 50, 88...8241, 47, 83913, 56487, 31, 37, 109, 115931, 37, 10915, 9914mitochondrial matrixcytosolcytosolmitochondrial matrixendosomelysosomal lumenlysosomal lumenendosomemitochondrial matrixPC unknown peptidaseVNN1 AASDHPPTMCCC2 Btn-ACACA 3xGPHN:3xMg2+PiH2OFAD 2xENPP1, 2xENPP2,2xENPP3H+MMAA MTRR:MTRCUBN Btn-PCCA SLC25A19LMBRD1PXLP GIF:CblCNCblSVCT1/2Food proteins MTRR PANK3 ATPH2OFMNL-CysMTRR:MTR(MeCbl)4x(PC:Mn2+)GIF:CblPPiMMACHCunknown peptidaseMetabolism of folateand pterinesFood proteinsVitCZn2+ CYB5A:ferrihemePantetheinePRSS1(16-18)2xTRAPDP-CoANAD+dADEACACB L-MetAMPCD320H2OhCBXs6x(Btn-MCCC1:MCCC2)TCII:CblGTPSLC52A3 PCCB holo-MOCS1NADP+VitCTCN2 cob(II)alaminPPANTMn2+ SLC19A3 MTR HCNNADPHPNPO AMN H+Btn-PCCA BCTNCUBN:AMNNicotinatemetabolismCblFAD TDPKFASNATPCoA-SHMOCS2 FMNMCCC2 TCN1H2OATPPDZD11 unknown peptidaseMMACHC:MMADHCMMACHC MCCC2 Zn2+ SLC5A6 MMADHC L-MM-CoACblBtn-PC CblPPiNa+ADPSUCC-CoACTRB2(19-31) PPiDHvitC2xAOX1:cofactorsunknown proteaseMg2+ FAD PCCB GIF (4Fe-4S)(2+) H2OBtn-PC Mn2+ PXAPBCTNPCCB AdoMet2xGSTOsBTDRFK COASYPAPTHMNMOCS1-1 2xMMAA:2xMUTSLC5A6:PDZD11AMPMTRR:MTR(cob(II)alamin)PXLP PiAMPCTRB1(19-31) PXLSLC5A6 ATPMTRR:MTR(cob(I)alamin)cob(I)alamin CUBN MMACHC ENPP3 GPHN MUT ATPsulfurated MoCoADP(4Fe-4S)(2+) Cbl MTRR CO2PPCS PPiTCN1TCIISLC23A1 THFAMPPrecursor ZRFK:Mg2+Btn-PC SLC2A3 MTR MCCC1 ThTPunknowncob(II)alaminreductaseCTRCPPiZn2+ PXACYB5A Mg2+ L-LysABCD4SLC19A2/3AdoMethCBXsPPicob(II)alamin TCII:CblNADP+PanKNADPHMoCoPPanKADPPCCA PRSS1(19-247)AdoCblGSHFASN2xENPP1Mn2+ MMADHC GIF MOCOS cob(I)alaminTCIIATPZn2+ TCII ATPENPP1 ATPTCN2 Cbl cob(II)alamin PANK2(111-570)TCN1 FADBtn-MCCC1 FADThDP6x(Btn-PCCA:PCCB)FLAD1GIF ADPPDZD11 NFS1-2 MMACHC:cob(II)alaminCbl 2xMMAA:2xMUT:AdoCblMMAB NH4+2xTPK1:Mg2+NADHMCCC2 AOX1 MOCS3 SLC2A1 FMN ATPTCN1:CblVNN1,VNN2ATPTPK1 SLC19A2 PPiTCII:Cbl:CD320PDXK PRSS1(16-247)2xPPCSMOCS3:Zn2+ (red.)H2OAMPAMPBCTNPCCB MOCS3:Zn2+ (ox.)FMN AMPSOG-MOCS2PDXPTCN1:CblAMPRIBCbl CYB5A 2xPDXK:2xZn2+GIF FAD ATPPPCBtn-ACACB heme Mg2+ ADPFAD Cbl ACACA MeCbl GIFSLC5A6:PDZD11CoA-SHATPACACA:2Mn2+GLUT1,3Btn-ACACA:2Mn2+3xMMABMn2+ ADP2xNFS1:2xPXLPPANK4 L-CysNa+CUBN CYB5A:hemeZn2+ CTRB2(167-263) Na+MTR FMN PXLPZn2+ PANK1/3/4MOCS1A Mg2+ Na+H2OL-Alacob(II)alamin ATPBtn-MCCC1 SLC23A2 Food proteins:Cbl2xMOCS2-CO-S(1-):2xMOCS2BCTRB1(34-164) MoO4(2-)MOCS2ACACB:2Mn2+CysS-MOCS3 BtnCbl L-AlaH2O2Cbl FeHM AMN L-CysHLCSRIBSOG-MOCS2 Cbl CoA-SHNa+ATPTCII BTDH2OVNN2 Cbl ACP5 MOCS2 AMPMOCS3 MUT PPCDC O2Mn2+ NADHGIF:CblENPP2 SLC52A2 Cbl GSSGH+MMACHC:MMADHC:cob(II)alaminSLC52A1 MDASCATPMMAA MTRR MPT 6xMCCC1:6xMCCC2BtnH2O2PPiTHMNMOCOS:PXLP2xPNPO:2xFMNBtn-MCCC1 CTRB2(34-164) H+GSTO2 MPTPPiMTR ABCC1DHvitCTHTPA:Mg2+5-methyl-THFPPANTPDXL-MetSLC52A1,2,3CYB5R3:FADADPCblPDXateThDPBtnNAD+AMN Zn2+ 2xMOCS2A:2xMOCS2BH2OTCII:CblSLC25A162AETPanKCD320 MTRR PiH2O3xPPCDC:3xFMNPANK1 MOCS2 PAPMOCS3-S-S(1-):Zn2+HCYSMMACHC Mn2+ Btn-PCCA ATPAdoCbl cob(II)alaminCblATPO2MMADHCATPFMN ENPP1 THTPA TCN1 Na+GSTO1 AdoHcyFAD BtnATPCUBN:AMN:GIF:CblPPiBtn-ACACB:2Mn2+ATPAMPCbl PRSS1(24-247) PPiPRSS1,3,CTRB1,2H2OATP6x(PCCA:PCCB)4x(Btn-PC:Mn2+)H2OMn2+ PPPH+FMN Mn2+ ADPPiADPL-LysHLCSMyrG-CYB5R3(2-301) PRSS3 CTRB1(167-263) CUBN:AMNFMN Zn2+ 9494944649, 92941059421, 10612294929494289494949494941229494